The nature of conditioned anti-analgesia: spinal cord opiate and anti-opiate neurochemistry

A METHOD FOR DETERMINING LOSS OF PAIN SENSATION

1941 • 3,174 citations

Endogenous Pain Control Systems: Brainstem Spinal Pathways and Endorphin Circuitry

1984 • 2,580 citations

Chronic catheterization of the spinal subarachnoid space

1976 • 2,244 citations

A perceptual-defensive-recuperative model of fear and pain

1980 • 811 citations

Organization of Endogenous Opiate and Nonopiate Pain Control Systems

1982 • 793 citations

Naltrindole, a highly selective and potent non-peptide δ opioid receptor antagonist

1988 • 599 citations

Isolation, sequencing, synthesis, and pharmacological characterization of two brain neuropeptides that modulate the action of morphine.

1985 • 594 citations

Evidence for the Neuropeptide Cholecystokinin as an Antagonist of Opiate Analgesia

1983 • 582 citations

The distribution of cholecystokinin immunoreactivity in the central nervous system of the rat as determined by radioimmunoassay

1981 • 545 citations

Behavioral and physiological studies of non-narcotic analgesia in the rat elicited by certain environmental stimuli

1978 • 416 citations

Stress-induced analgesia: adaptive pain suppression

1986 • 370 citations

Antagonism of stimulation-produced analgesia by p-CPA, a serotonin synthesis inhibitor

1972 • 284 citations

Potentiation of Opiate Analgesia and Apparent Reversal of Morphine Tolerance by Proglumide

1984 • 269 citations

Long-Term Stress-Induced Analgesia and Activation of the Opiate System

1981 • 266 citations

Autoradiographic localization of cholecystokinin receptors in rodent brain

1983 • 259 citations

The role of CCK, caerulein, and CCK antagonists in nociception

1989 • 246 citations

Conditioned Fear‐Induced Opiate Analgesia: A Competing Motivational State Theory of Stress Analgesia^a

1986 • 238 citations

Proglumide and benzotript: members of a different class of cholecystokinin receptor antagonists.

1981 • 231 citations

Inhibition of spontaneous and opiate-modified nociception by an endogenous neuropeptide with Phe-Met-Arg-Phe-NH2-like immunoreactivity.

1984 • 213 citations

Conditional analgesia, defensive freezing, and benzodiazepines.

1988 • 199 citations

Caerulein and cholecystokinin suppress β-endorphin-induced analgesia in the rat

1982 • 195 citations

Role of safety in the Pavlovian backward fear conditioning procedure.

1968 • 166 citations

Multiple Endogenous Opiate and Non‐Opiate Analgesia Systems: Evidence of Their Existence and Clinical Implications^a

1986 • 165 citations

Exposure to a cat produces opioid analgesia in rats.

1985 • 161 citations

Exposure to a cat produces opioid analgesia in rats.

1985 • 158 citations

Conditional analgesia, defensive freezing, and benzodiazepines.

1988 • 157 citations

Potentiation of morphine analgesia by the cholecystokinin antagonist proglumide

1985 • 156 citations

Cholecystokinin Antianalgesia: Safety Cues Abolish Morphine Analgesia

1992 • 138 citations

Binaltorphimine-related bivalent ligands and their .kappa. opioid receptor antagonist selectivity

1988 • 137 citations

Classical conditioning of front paw and hind paw footshock induced analgesia (FSIA): Naloxone reversibility and descending pathways

1982 • 136 citations

Cholecystokinin antagonists selectively potentiate analgesia induced by endogenous opiates

1985 • 136 citations

Existence of antiopiate systems as illustrated by MIF-1/Tyr-MIF-1

1986 • 122 citations

MIF-I's differential actions as an opiate antagonist

1979 • 121 citations

Differential interactions of cholecystokinin and FLFQPQRF-NH2 with μ and δ opioid antinociception in the rat spinal cord

1990 • 115 citations

The opioid/nonopioid nature of stress-induced analgesia and learned helplessness.

1983 • 110 citations

IgG from neuropeptide FF antiserum reverses morphine tolerance in the rat

1991 • 109 citations

Cholecystokinin antianalgesia: safety cues abolish morphine analgesia

1992 • 103 citations

Opioid receptor subtypes in the rat spinal cord: electrophysiological studies with μ- and δ-opioid receptor agonists in the control of nociception

1987 • 99 citations

IgG from antiserum against endogenous mammalian FMRF-NH2-related peptides augments morphine- and stress-induced analgesia in mice

1989 • 98 citations

Cyclic somatostatin octapeptide analogues with high affinity and selectivity toward mu opioid receptors

1986 • 98 citations

Stress-Induced Analgesia

2006 • 94 citations

Determinants of the nature of environmentally induced hypoalgesia.

1989 • 86 citations

Characterization and localization of a putative morphine-modulating peptide, FLFQPQRfamide, in the rat spinal cord: Biochemical and immunocytochemical studies

1991 • 83 citations

Proglumide prevents and curtails acute tolerance to morphine in rats

1984 • 80 citations

Origin and distribution of neuropeptide‐FF‐like immunoreactivity in the spinal cord of rats

1991 • 76 citations

Spinal dynorphin A (1–17): Possible mediator of antianalgesic action

1990 • 73 citations

Species-specific danger signals, endogenous opioid analgesia, and defensive behavior.

1986 • 67 citations

The opioid/nonopioid nature of stress-induced analgesia and learned helplessness.

1983 • 66 citations

Intrathecally administered dynorphin-(1–17) modulates morphine-induced antinociception differently in morphine-naive and morphine-tolerant rats

1987 • 62 citations

Involvement of spinal opioid systems in footshock-induced analgesia: Antagonism by naloxone is possible only before induction of analgesia

1982 • 62 citations

Parallel activation of multiple spinal opiate systems appears to mediate ‘non-opiate’ stress-induced analgesias

1992 • 60 citations

Species-specific danger signals, endogenous opioid analgesia, and defensive behavior.

1986 • 51 citations

Analog of neuropeptide FF attenuates morphine tolerance

1992 • 49 citations

Kappa opiate receptors mediate tail-shock induced antinociception at spinal levels

1992 • 49 citations

Stress-Induced Analgesia

1987 • 42 citations

Opioid and nonopioid conditional analgesia: The role of spinal opioid, noradrenergic, and serotonergic systems.

1991 • 30 citations

Comparisons of descending pain inhibitory pathways activated by beta-endorphin and morphine as characterized by supraspinal and spinal antinociceptive interactions in mice.

1988 • 28 citations

Strain differences in reversal of conditional analgesia by opioid antagonists.

1987 • 27 citations

Opioid and nonopioid conditional analgesia: The role of spinal opioid, noradrenergic, and serotonergic systems.

1991 • 27 citations

Delta opiate receptors mediate tail-shock induced antinociception at supraspinal levels

1992 • 24 citations

Strain differences in reversal of conditional analgesia by opioid antagonists.

1987 • 23 citations

Neurochemistry of the Dorsal Horn

1988 • 21 citations

Conditioned inhibition of analgesia

1992 • 21 citations

Conditioned and unconditioned stress-induced analgesia: Stimulus preexposure and stimulus change

1991 • 19 citations

Interaction of Cholecystokinin and Opioids in Pain Modulation

1987 • 12 citations

BEHAVIORAL EVIDENCE FOR THE EXISTENCE OF ???ANTI-ANALGESIA??? SYSTEMS

1992 • 3 citations