Differential interactions of cholecystokinin and FLFQPQRF-NH2 with μ and δ opioid antinociception in the rat spinal cord

Isolation, sequencing, synthesis, and pharmacological characterization of two brain neuropeptides that modulate the action of morphine.

1985 • 594 citations

Evidence for the Neuropeptide Cholecystokinin as an Antagonist of Opiate Analgesia

1983 • 582 citations

The Physiology and Pharmacology of Spinal Opiates

1985 • 303 citations

Electrophysiological studies on the effects of intrathecal morphine on nociceptive neurones in the rat dorsal horn

1986 • 273 citations

Inhibition of spontaneous and opiate-modified nociception by an endogenous neuropeptide with Phe-Met-Arg-Phe-NH2-like immunoreactivity.

1984 • 213 citations

Potentiation of morphine analgesia by the cholecystokinin antagonist proglumide

1985 • 156 citations

Studies on the location and release of cholecystokinin and vasoactive intestinal peptide in rat and cat spinal cord

1982 • 147 citations

Existence of antiopiate systems as illustrated by MIF-1/Tyr-MIF-1

1986 • 122 citations

Localization and opiate receptor binding of enkephalin, CCK and ACTH/β-endorphin in the rat central nervous system

1981 • 105 citations

Opioid receptor subtypes in the rat spinal cord: electrophysiological studies with μ- and δ-opioid receptor agonists in the control of nociception

1987 • 99 citations

FMRFamide-like immunoreactivity in rat brain: Development of a radioimmunoassay and its application in studies of distribution and chromatographic properties

1983 • 89 citations

Autoradiographic study of μ and δ opioid binding sites and neutral endopeptidase-24.11 in rat after dorsal root rhizotomy

1989 • 77 citations

Intrathecal cholecystokinin interacts with morphine but not substance P in modulating the nociceptive flexion reflex in the rat

1987 • 55 citations

Evidence that endogenous enkephalins produce δ-opiate receptor mediated neuronal inhibitions in rat dorsal horn

1986 • 34 citations

Neurotransmitters and Pain Control

1987 • 30 citations

The effects of C-terminal fragments of cholecystokinin on the firing of single neurones in the caudal trigeminal nucleus of the rat

1982 • 27 citations

Peripheral and central origin of Phe-Met-Arg-Phe-amide immunoreactivity in rat spinal cord

1986 • 24 citations

Neurotransmitters and pain control

1988 • 21 citations

Cholecystokinin and Pain

1987 • 20 citations

Central administration of cholecystokinin potentiates evoked potential amplitude in the hippocampal dentate gyrus

1988 • 7 citations

Cholecystokinin and an evoked response in the dentate gyrus

1988 • 2 citations