Therapy with antibody against leukocyte integrin VLA-4 (CD49d) is effective and safe in virus-facilitated experimental allergic encephalomyelitis

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Adhesion receptors of the immune system

1990 • 6,585 citations

Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin

1992 • 1,711 citations

Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein

1995 • 1,528 citations

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.

1993 • 837 citations

Cellular immune reactivity within the CNS

1986 • 771 citations

Biology of disease. Analysis of autoimmune demyelination: its impact upon multiple sclerosis.

1984 • 424 citations

Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins.

1994 • 391 citations

Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system.

1990 • 388 citations

The pathophysiologic role of alpha 4 integrins in vivo.

1994 • 380 citations

Animal models

1994 • 276 citations

Viral infections trigger multiple sclerosis relapses: a prospective seroepidemiological study

1993 • 264 citations

The adhesion molecules used by monocytes for migration across endothelium include CD11a/CD18, CD11b/CD18, and VLA-4 on monocytes and ICAM-1, VCAM-1, and other ligands on endothelium.

1995 • 247 citations

Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptor on macrophages

1990 • 245 citations

Inhibition of experimental autoimmune encephalomyelitis by an antibody to the intercellular adhesion molecule ICAM‐1

1993 • 186 citations

The role of PECAM-1 (CD31) in leukocyte emigration: studies in vitro and in vivo

1995 • 183 citations

Upregulation and coexpression of adhesion molecules correlate with relapsing autoimmune demyelination in the central nervous system.

1990 • 173 citations

Expression of immunologically relevant endothelial cell activation antigens on isolated central neurvous system microvessels from patients with multiple sclerosis

1994 • 170 citations

Bothanti-CD11a(LFA-l) and anti-CD11b (MAC-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis

1995 • 120 citations

Multiple sclerosis: a pivotal role for the T cell in lesion development

1991 • 118 citations

Adhesion molecule expression on cerebrospinal fluid T lymphocytes: Evidence for common recruitment mechanisms in multiple sclerosis, aseptic meningitis, and normal controls

1993 • 114 citations

Changes in cell adhesion molecule expression on T cells associated with systemic virus infection.

1994 • 113 citations

Treatment with anti‐CR3 antibodies ED7 and ED8 suppresses experimental allergic encephalomyelitis in Lewis rats

1993 • 96 citations

In vivo depletion of CD8+ T cells prevents lesions of demyelination in Semliki Forest virus infection

1993 • 76 citations

ICAM-1-dependent pathway is not critically involved in the inflammatory process of autoimmune encephalomyelitis or in cytokine-induced inflammation of the central nervous system

1993 • 75 citations

Antibody to the murine type 3 complement receptor inhibits T lymphocyte-dependent recruitment of myelomonocytic cells in vivo.

1989 • 70 citations

A Method for the Covalent Attachment of Cells to Glass Slides for Use in Immunohlstochemlcal Assays

1985 • 69 citations

Semliki Forest virus infects mouse brain endothelial cells and causes blood-brain barrier damage

1994 • 68 citations

Antibodies against Leukocyte Function-Associated Antigen-1 and against Intercellular Adhesion Molecule-1 Together Suppress the Progression of Experimental Allergic Encephalomyelitis

1995 • 56 citations

Virus-activated T cells regulate expression of adhesion molecules on endothelial cells in sites of infection

1995 • 47 citations

Blood-brain barrier breakdown and increased intercellular adhesion molecule (ICAM-1/CD54) expression after Semliki Forest ( A7) virus infection facilitates the development of experimental allergic encephalomyelitis

1996 • 39 citations

Effect of viral infection on experimental allergic encephalomyelitis in mice

1988 • 25 citations

Circulating intercellular adhesion molecule-1 (ICAM-1) as an early and sensitive marker for virus-induced T cell activation

1995 • 16 citations

Facilitation of experimental allergic encephalomyelitis by irradiation and virus infection: role of inflammatory cells

1994 • 13 citations