DNA methylation of three 5' C-C-G-G 3' sites in the promoter and 5' region inactivate the E2a gene of adenovirus type 2.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes.

1977 • 2,233 citations

DNA Methylation and Gene Function

1980 • 2,069 citations

A dye-buoyant-density method for the detection and isolation of closed circular duplex DNA: the closed circular DNA in HeLa cells.

1967 • 1,317 citations

DNA METHYLATION AND GENE ACTIVITY

1983 • 1,115 citations

Multiple new phenotypes induced in and 3T3 cells treated with 5-azacytidine

1979 • 1,101 citations

Effects of methylation on a synthetic polynucleotide: the B--Z transition in poly(dG-m5dC).poly(dG-m5dC).

1981 • 873 citations

5-Methylcytosine in Eukaryotic DNA

1981 • 744 citations

Reactivation of an Inactive Human X Chromosome: Evidence for X Inactivation by DNA Methylation

1981 • 711 citations

5-Azacytidine Selectively Increases γ-Globin Synthesis in a Patient with β⁺Thalassemia

1982 • 496 citations

Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation

1981 • 475 citations

DNA methylation and the regulation of globin gene expression

1983 • 451 citations

5-Methylcytosine, Gene Regulation, and Cancer

1983 • 425 citations

MspI, an isoschizomer of HpaII which cleaves both unmethylated and methylated HpaII sites

1978 • 395 citations

Functional striated muscle cells from non-myoblast precursors following 5-azacytidine treatment

1977 • 335 citations

Methylation of integrated adenovirus type 12 DNA sequences in transformed cells is inversely correlated with viral gene expression.

1980 • 309 citations

Promoters and heterogeneous 5′ termini of the messenger RNAs of adenovirus serotype 2

1981 • 289 citations

In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells.

1982 • 271 citations

Specificity of<u>Hpa</u>II and<u>Hae</u>II DNA methylases

1977 • 221 citations

Differentiation of Cells of the Rana pipiens Gastrula in Unconditioned Medium1

1959 • 198 citations

DNA Methylation--A Regulatory Signal in Eukaryotic Gene Expression

1981 • 192 citations

Expression of a cloned adenovirus gene is inhibited by in vitro methylation.

1982 • 184 citations

Pattern of methylation of two genes coding for housekeeping functions.

1983 • 148 citations

Estrogen induces a demethylation at the 5' end region of the chicken vitellogenin gene.

1982 • 142 citations

Expression of the chloramphenicol acetyltransferase gene in mammalian cells under the control of adenovirus type 12 promoters: effect of promoter methylation on gene expression.

1983 • 139 citations

DNA methylation and viral gene expression in adenovirus-transformed and-infected cells

1980 • 131 citations

Undermethylation at the 5′ end of the albumin gene is necessary but not sufficient for albumin production by rat hepatoma cells in culture

1982 • 124 citations

Integration Sites of Adenovirus Type 12 DNA in Transformed Hamster Cells and Hamster Tumor Cells

1980 • 118 citations

Retrovirus genomes methylated by mammalian but not bacterial methylase are non-infectious

1983 • 98 citations

Transfer of Cell Constituents into Eukaryotic Cells

1980 • 87 citations

Methylation of simian virus 40 Hpa II site affects late, but not early, viral gene expression.

1982 • 85 citations

The unmethylated state of the promoter/leader and 5′-regions of integrated adenovirus genes correlates with gene expression.

1982 • 79 citations

Effect of methylation on expression of microinjected genes.

1982 • 61 citations

DNA methylation in chicken alpha-globin gene expression.

1982 • 58 citations

Methylation of Integrated Viral DNA Sequences in Hamster Cells Transformed by Adenovirus 12

1980 • 54 citations

Transcription in oocytes of highly methylated rDNA from Xenopus laevis sperm

1983 • 53 citations

Expression of Viral DNA in Adenovirus Type 12-Transformed Cells, in Tumor Cells, and in Revertants

1981 • 47 citations

Methylation of adenovirus genes in transformed cells and in vitro: influence on the regulation of gene expression?

1981 • 35 citations

DNA Methylation and Its Functional Significance: Studies on the Adenovirus System

1984 • 34 citations

Coupled Demethylation of Sites in a Conserved Sequence of Xenopus Ribosomal DNA

1983 • 33 citations

Structure and Expression of the Human Globin Genes and Murine Histoeompatability Antigen Genes

1983 • 22 citations

In Vitro Methylation of theBsuRI (5′-GGCC-3′) Sites in the E2a Region of Adenovirus Type 2 DNA Does Not Affect Expression inXenopus laevisOocytes

1982 • 22 citations

In Vitro Methylation of the BsuRI (5′-GGCC-3′) Sites in the E2a Region of Adenovirus Type 2 DNA Does Not Affect Expression in Xenopus laevis Oocytes

1982 • 3 citations