Retrovirus genomes methylated by mammalian but not bacterial methylase are non-infectious

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

Nucleotide sequence of Moloney murine leukaemia virus

1981 • 1,079 citations

Effects of methylation on a synthetic polynucleotide: the B--Z transition in poly(dG-m5dC).poly(dG-m5dC).

1981 • 873 citations

5-Methylcytosine in Eukaryotic DNA

1981 • 744 citations

Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine.

1982 • 575 citations

De novo methylation and expression of retroviral genomes during mouse embryogenesis

1982 • 524 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1962 • 466 citations

Substrate and sequence specificity of a eukaryotic DNA methylase

1982 • 441 citations

The somatic replication of DNA methylation

1981 • 368 citations

Chromosomal position and activation of retroviral genomes inserted into the germ line of mice

1981 • 344 citations

De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells.

1982 • 299 citations

In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells.

1982 • 271 citations

DNA methylation and gene expression: endogenous retroviral genome becomes infectious after molecular cloning.

1981 • 231 citations

Specificity of<u>Hpa</u>II and<u>Hae</u>II DNA methylases

1977 • 221 citations

Methylation and gene control

1982 • 210 citations

Biochemistry of S-Adenosylmethionine and Related Compounds

1982 • 185 citations

Expression of a cloned adenovirus gene is inhibited by in vitro methylation.

1982 • 184 citations

Infectivity and methylation of retroviral genomes is correlated with expression in the animal

1981 • 165 citations

Undermethylation at the 5′ end of the albumin gene is necessary but not sufficient for albumin production by rat hepatoma cells in culture

1982 • 124 citations

Integration of Moloney leukaemia virus into the germ line of mice: correlation between site of integration and virus activation

1980 • 121 citations

Loss of rDNA methylation accompanies the onset of ribosomal gene activity in early development of X. laevis

1981 • 116 citations

DNA methylation affecting the expression of murine leukemia proviruses

1982 • 99 citations

DNA-methylase from regenerating rat liver: purification and characterisation

1978 • 99 citations

Studies on gene control regions XII. The functional significance of a Lac operator constitutive mutation

1979 • 84 citations

The unmethylated state of the promoter/leader and 5′-regions of integrated adenovirus genes correlates with gene expression.

1982 • 79 citations

Transformation of NIH/3T3 mouse cells by DNA of Rous sarcoma virus

1979 • 77 citations

Cloning of Two Genetically Transmitted Moloney Leukemia Proviral Genomes: Correlation Between Biological Activity of the Cloned DNA and Viral Genome Activation in the Animal

1982 • 66 citations

The structure of the thymidine kinase gene promoter: Nuclease hypersensitivity correlates with expression

1982 • 63 citations

Effect of methylation on expression of microinjected genes.

1982 • 61 citations

Tissue specificity and clustering of methylated cystosines in bovine satellite I DNA.

1982 • 46 citations

In Vitro Methylation of Specific Regions of the Cloned Moloney Sarcoma Virus Genome Inhibits Its Transforming Activity

1983 • 42 citations

Isolation and characterization of two proteins possessing Hpa II methylase activity.

1980 • 37 citations

Endogenous Moloney leukemia virus in nonviremic Mov substrains of mice carries defects in the proviral genome

1983 • 31 citations

In vitro methylation of specific regions of the cloned Moloney sarcoma virus genome inhibits its transforming activity.

1983 • 29 citations

Effect of DNA methylation in vitro on the expression of SV40 and VSPV

1982 • 2 citations