Displacement of rhodopsin by GDP from three-loop interaction with transducin depends critically on the diphosphate beta-position.

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Cyclic GMP Cascade of Vision

1986 • 1,168 citations

Flow of information in the light-triggered cyclic nucleotide cascade of vision.

1981 • 740 citations

A family of receptors coupled to guanine nucleotide regulatory proteins

1987 • 636 citations

Site of G Protein Binding to Rhodopsin Mapped with Synthetic Peptides from the α Subunit

1988 • 491 citations

Lithium inhibits adrenergic and cholinergic increases in GTP binding in rat cortex

1988 • 474 citations

Fluoroaluminates activate transducin‐GDP by mimicking the γ‐phosphate of GTP in its binding site

1985 • 420 citations

Three cytoplasmic loops of rhodopsin interact with transducin.

1989 • 370 citations

Molecular biology of the visual pigments

1986 • 335 citations

Molecular mechanism of visual transduction

1989 • 312 citations

Interactions between photoexcited rhodopsin and GTP-binding protein: kinetic and stoichiometric analyses from light-scattering changes.

1981 • 247 citations

The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide-binding regulatory proteins.

1987 • 190 citations

The transitory complex between photoexcited rhodopsin and transducin

1989 • 129 citations

A procedure for rapid extraction and high-pressure liquid chromatographic separation of the nucleotides and other small molecules from bacterial cells

1982 • 123 citations

The G-protein of retinal rod outer segments (transducin). Mechanism of interaction with rhodopsin and nucleotides.

1985 • 122 citations

Stereochemistry of the guanyl nucleotide binding site of transducin probed by phosphorothioate analogs of GTP and GDP

1985 • 102 citations

Shift in the relation between flash‐induced metarhodopsin I and metarhodopsin II within the first 10% rhodopsin bleaching in bovine disc membranes

1981 • 70 citations

Dual Mg²⁺ control of formyl‐peptide‐receptor–G‐protein interaction in HL 60 cells

1989 • 69 citations

Topographic analysis of antigenic determinants recognized by monoclonal antibodies to the photoreceptor guanyl nucleotide-binding protein, transducin.

1987 • 68 citations

Photoactivation of rhodopsin and interaction with transducin in detergent micelles

1989 • 51 citations

Interaction of retinal transducin with guanosine triphosphate analog: specificity of the .gamma.-phosphate binding region

1986 • 50 citations

Kinetic study on the equilibrium between membrane-bound and free photoreceptor G-protein

1987 • 50 citations

Effect of GTP on the rhodopsin-G-protein complex by transient formation of extra metarhodopsin II

1985 • 37 citations

A structural model for the α‐subunit of transducin Implications of its role as a molecular switch in the visual signal transduction mechanism

1987 • 36 citations

Temperature dependence of G-protein activation in photoreceptor membranes. Transient extra metarhodopsin II on bovine disk membranes

1987 • 35 citations

Mutations Probe Structure and Function of G-protein Chains

1988 • 34 citations

The effect of GDP on rod outer segment G-protein interactions.

1990 • 29 citations

Light and GTP dependence of transducin solubility in retinal rods

1988 • 27 citations

Comparative kinetic light-scattering and -absorption photometry

1981 • 21 citations

The kinetic mechanism of the release of nucleotide from elongation factor Tu promoted by elongation factor Ts determined by pressure relaxation studies.

1988 • 15 citations