Altered genetic response to β‐adrenergic receptor activation in late passage C6 glioma cells

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

1989 • 2,486 citations

Differentiated Rat Glial Cell Strain in Tissue Culture

1968 • 1,480 citations

CREB: a Ca ²⁺ -Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases

1991 • 1,476 citations

Isolation and Characterization of Full-Length cDNA Clones for Human α-, β-, and γ-Actin mRNAs: Skeletal but Not Cytoplasmic Actins Have an Amino-Terminal Cysteine that Is Subsequently Removed

1983 • 1,220 citations

Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB

1990 • 1,061 citations

A cyclic AMP- and phorbol ester-inducible DNA element

1986 • 780 citations

Induction of proto-oncogene JUN/AP-1 by serum and TPA

1988 • 689 citations

FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA

1982 • 668 citations

Replicative Senescence: the Human Fibroblast Comes of Age

1990 • 649 citations

Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription.

1986 • 548 citations

Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed.

1983 • 546 citations

Regulation of Proenkephalin by Fos and Jun

1989 • 546 citations

Rat brain preproenkephalin mRNA. cDNA cloning, primary structure, and distribution in the central nervous system.

1984 • 540 citations

Repression of c- fos Transcription and an Altered Genetic Program in Senescent Human Fibroblasts

1990 • 478 citations

Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor

1983 • 474 citations

Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element.

1988 • 391 citations

Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments.

1984 • 352 citations

Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts.

1985 • 344 citations

The promoter of Alzheimer's disease amyloid A4 precursor gene.

1988 • 309 citations

Multiple sequence elements in the c-fos promoter mediate induction by cAMP.

1989 • 225 citations

Isolation and characterization of the rat proenkephalin gene.

1984 • 194 citations

"Transdifferentiation" of C6 Glial Cells in Culture

1980 • 175 citations

Regulation of nerve growth factor biosynthesis by beta-adrenergic receptor activation in astrocytoma cells: a potential role of c-Fos protein.

1989 • 149 citations

Cell‐Specific Expression of the Mouse Glial Fibrillary Acidic Protein Gene: Identification of the Cis‐ and Trans‐Acting Promoter Elements for Astrocyte‐Specific Expression

1990 • 133 citations

Astrocytes regulate GFAP mRNA levels by cyclic AMP and protein kinase C‐dependent mechanisms

1988 • 114 citations

Reversal of Catecholamine Refractoriness by Inhibitors of RNA and Protein Synthesis

1974 • 111 citations

Early and late passage C-6 glial cell growth: Similarities with primary glial cells in culture

1989 • 96 citations

Interleukin-1 stimulates the beta-amyloid precursor protein promoter

1990 • 95 citations

Expression of the enkephalin precursor gene in C6 rat glioma cells: Regulation by β-adrenergic agonists and glucocorticoids

1986 • 76 citations

TIS gene expression in cultured rat astrocytes: Induction by mitogens and stellation agents

1989 • 75 citations

Noradrenaline induces morphological alterations in nucleated and enucleated rat C6 glioma cells

1975 • 71 citations

Structural and functional analysis of the promoter region of the nerve growth factor gene

1988 • 66 citations

Induction of protooncogene fos by extracellular signals in primary glial cell cultures

1989 • 60 citations

Tis gene expression in cultured rat astrocytes: Multiple pathways of induction by mitogens

1989 • 58 citations

Characterization of a cDNA clone encoding murine mitogen-regulated protein: regulation of mRNA levels in mortal and immortal cell lines.

1985 • 54 citations

Stimulation of nerve growth factor mRNA content in C6 glioma cells by a β‐adrenergic receptor and by cyclic AMP

1988 • 52 citations

A novel species-specific RNA related to alternatively spliced amyloid precursor protein mRNAs

1991 • 51 citations

A new cAMP response element in the transcribed region of the human c-fos gene

1991 • 42 citations

Transient increase in intracellular concentration of adenosine 3′:5′‐cyclic monophosphate results in morphological and biochemical differentiation of C₆ glioma cells in culture

1987 • 38 citations

Malignant transformation and tumor promoter treatment increase levels of a transcript for a secreted glycoprotein.

1985 • 25 citations

Altered regulation of platelet-derived growth factor A-chain and c-fos gene expression in senescent progeria fibroblasts

1990 • 24 citations

Multiple forms of beta-amyloid peptide precursor RNAs in a single cell type

1988 • 21 citations

Activation of adenosine receptors induces c-fos, but not c-jun, expression in neuron-glia hybrids and fibroblasts

1990 • 21 citations

Differences in the β-adrenergic responsiveness between high and low passage rat glioma C6 cells

1981 • 19 citations

Preproenkephalin DNA-binding proteins in the rat: 5′ flanking region

1989 • 18 citations

Beta-adrenergic receptor regulation of NGF-mRNA content in rat C6-2b glioma cells

1987 • 16 citations

β‐Adrenergic treatment of C6 glioma cells produces opposite changes in c‐fos and c‐jun mRNA levels

1991 • 10 citations

Dr. August Weismann on the Importance of Sexual Reproduction for the theory of Selection 1

1886 • 6 citations

Density-dependent nerve growth factor regulation of Gs-alpha RNA in pheochromocytoma 12 cells.

1990 • 5 citations