Tis gene expression in cultured rat astrocytes: Multiple pathways of induction by mitogens

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue.

1980 • 3,822 citations

Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells.

1981 • 1,655 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1988 • 1,278 citations

Epidermal Growth Factor and a New Derivative

1972 • 1,225 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

Basic Neurochemistry: Molecular, Cellular, and Medical Aspects

1989 • 837 citations

Steroid Receptors: Elements for Modulation of Eukaryotic Transcription

1976 • 688 citations

Disappearance of Ca2+-sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cells

1984 • 643 citations

Complexity of the early genetic response to growth factors in mouse fibroblasts.

1988 • 579 citations

Superinduction of c- fos by Nerve Growth Factor in the Presence of Peripherally Active Benzodiazepines

1985 • 478 citations

c-myc gene expression is stimulated by agents that activate protein kinase C and does not account for the mitogenic effect of PDGF

1985 • 331 citations

Specific high-affinity binding sites for [3H]Ro 5-4864 in rat brain and kidney.

1983 • 296 citations

A novel early growth response gene rapidly induced by fibroblast, epithelial cell and lymphocyte mitogens.

1987 • 292 citations

Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts.

1986 • 241 citations

Epidermal growth factor binding and mitogenic activity on purified populations of cells from the central nervous system

1982 • 206 citations

Epidermal growth factor stimulates DNA-synthesis of astrocytes in primary cerebellar cultures

1981 • 197 citations

Dopamine and serotonin inhibition of neurite elongation of different identified neurons

1988 • 174 citations

Influence of epidermal growth factor (EGF) on ruffling activity, pinocytosis and proliferation of cultivated human glia cells

1976 • 165 citations

Complexity of the Early Genetic Response to Growth Factors in Mouse Fibroblasts

1988 • 159 citations

Density dependent proliferation of human glia cells stimulated by epidermal growth factor

1976 • 150 citations

Insulin and growth factor effects on c-fos expression in normal and protein kinase C-deficient 3T3-L1 fibroblasts and adipocytes.

1986 • 137 citations

Induction of transiently expressed genes in PC-12 pheochromocytoma cells.

1987 • 109 citations

Protein kinase C-dependent and -independent pathways of proto-oncogene induction in human astrocytoma cells.

1987 • 99 citations

Platelet-derived growth factor-inducible genes respond differentially to at least two distinct intracellular second messengers.

1987 • 84 citations

TIS gene expression in cultured rat astrocytes: Induction by mitogens and stellation agents

1989 • 75 citations

Growth factors for human glial cells in culture

1988 • 70 citations

Development expression of glial‐specific mRNAs in primary cultures of rat brain visualized by in situ hybridization

1988 • 69 citations

Phorbol ester stimulates proliferation of astrocytes in primary culture

1987 • 61 citations

Induction of tumor promotor-inducible genes in murine 3T3 cell lines and tetradecanoyl phorbol acetate-nonproliferative 3T3 variants can occur through protein kinase C-dependent and -independent pathways.

1989 • 59 citations

Effect of benzodiazepines and pentobarbital on the GABA‐induced depolarization in cultured astrocytes

1988 • 55 citations

Cell activation: The ‘basic’ connection

1984 • 50 citations

Dissociation of the Stellate Morphology from Intracellular Cyclic AMP Levels in Cultured Rat Brain Astroglial Cells: Effects of Ganglioside GMland Lysophosphatidylserine

1987 • 49 citations

Effects of maturational agents on expression and secretion of two partially characterized high molecular weight milk‐related glycoproteins in MCF‐7 breast carcinoma cells

1986 • 49 citations

Gangliosides stimulate astroglial cell proliferation in the absence of serum

1986 • 48 citations

Inhibition of cell proliferation of human gliomas by benzodiazepinesin vitro

1988 • 39 citations

Binding of [3H]Ro 5–4864 in primary cultures of astrocytes

1985 • 33 citations

Characteristics of an atypical benzodiazepine, Ro 5-4864

1984 • 28 citations

"Sub-threshold neoplastic states" created in transgenic mice.

1987 • 15 citations

Ionic responses and growth stimulation in rat astroglial cells: Differential mechanisms of gangliosides and serum

1987 • 14 citations

Ganglioside GM1 actions on cell‐substratum adhesion and DNA synthesis by cultured astroglial cells

1988 • 13 citations

Book-Review - Einstein's Legacy - the Unity of Space and Time

1987 • 10 citations

Benzodiazepine Receptor Development in Murine Glial Cultures

1987 • 10 citations

Cometary showers and unseen solar companions (reply)

1984 • 3 citations

Chronic HIV-infection in CNS - Neurological manifestations.

1988 • 3 citations