Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae

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1989 • 8,705 citations

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[12] One-step gene disruption in yeast

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1990 • 1,922 citations

Elevated recombination rates in transcriptionally active DNA

1989 • 1,666 citations

The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest.

1991 • 1,489 citations

The distribution of the numbers of mutants in bacterial populations

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Methods in Yeast Genetics — A Laboratory Course Manual

1991 • 1,257 citations

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1979 • 1,080 citations

Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae

1991 • 700 citations

Identification of a New Family of Tissue-Specific Basic Helix-Loop-Helix Proteins with a Two-Hybrid System

1995 • 655 citations

Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1.

1994 • 547 citations

Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways.

1996 • 492 citations

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance

1996 • 478 citations

SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres

1993 • 392 citations

Epigenetic inheritance of transcriptional states in S. cerevisiae

1989 • 327 citations

Silencers, silencing, and heritable transcriptional states

1992 • 296 citations

Mutations in Two Ku Homologs Define a DNA End-Joining Repair Pathway in Saccharomyces cerevisiae

1996 • 275 citations

The DNA-binding Protein Hdf1p (a Putative Ku Homologue) Is Required for Maintaining Normal Telomere Length in Saccharomyces Cerevisiae

1996 • 246 citations

A Deubiquitinating Enzyme Interacts with SIR4 and Regulates Silencing in S. cerevisiae

1996 • 228 citations

Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length.

1991 • 218 citations

Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast.

1995 • 196 citations

What to do at an end: DNA double-strand-break repair

1995 • 195 citations

Chromosomal double-strand break repair in Ku80-deficient cells.

1996 • 191 citations

The Saccharomyces cerevisiae Ku Autoantigen Homologue Affects Radiosensitivity Only in the Absence of Homologous Recombination

1996 • 189 citations

A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae

1993 • 171 citations

Effects of Mutations of RAD50, RAD51, RAD52, and Related Genes on Illegitimate Recombination in Saccharomyces cerevisiae

1996 • 97 citations

Hdf1, a yeast Ku-protein homologue, is involved in illegitimate recombination, but not in homologous recombination

1996 • 54 citations