Adenosine receptor ligands: differences with acute versus chronic treatment

Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects

1992 • 1,392 citations

Adenosine, Adenosine Receptors and the Actions of Caffeine *

1995 • 563 citations

Neuroprotective role of adenosine in cerebral ischaemia

1992 • 450 citations

Cloned adenosine A3 receptors: Pharmacological properties, species differences and receptor functions

1994 • 395 citations

Adenosine-dopamine interactions in the brain

1992 • 366 citations

Adenosine A3 receptor stimulation and cerebral ischemia

1994 • 272 citations

Downregulation of nicotinic receptor function after chronic nicotine infusion.

1993 • 181 citations

Caffeine, coffee, and health

1993 • 172 citations

Chronic caffeine alters the density of adenosine, adrenergic, cholinergic, GABA, and serotonin receptors and calcium channels in mouse brain

1993 • 162 citations

Should caffeine abuse, dependence, or withdrawal be added to DSM-IV and ICD-10?

1992 • 149 citations

Effect of long term caffeine treatment on A1 and A2 adenosine receptor binding and on mRNA levels in rat brain

1993 • 143 citations

Differences in the regional and cellular localization of c-fos messenger RNA induced by amphetamine, cocaine and caffeine in the rat

1994 • 142 citations

Cerebral ischemia in gerbils: effects of acute and chronic treatment with adenosine A2A receptor agonist and antagonist

1995 • 138 citations

Biphasic changes in locomotor behavior and in expression of mRNA for NGFI-A and NGFI-B in rat striatum following acute caffeine administration

1995 • 129 citations

A role for mast cells in adenosine A³ receptor‐mediated hypotension in the rat

1995 • 128 citations

Ischaemic damage in gerbil hippocampus is reduced following upregulation of adenosine (A1) receptors by caffeine treatment

1989 • 118 citations

CGS 15943, An adenosine A2 receptor antagonist, reduces cerebral ischemic injury in the mongolian gerbil

1994 • 117 citations

Role of adenosine receptors in caffeine tolerance.

1991 • 111 citations

N-methyl-D-aspartate antagonists and working memory performance: Comparison with the effects of scopolamine, propranolol, diazepam, and phenylisopropyladenosine.

1991 • 104 citations

Behavioral effects of A1- and A2-selective adenosine agonists and antagonists: evidence for synergism and antagonism.

1991 • 103 citations

Chronic administration of selective adenosine A1 receptor agonist or antagonist in cerebral ischemia

1994 • 102 citations

Long-term caffeine treatment leads to a decreased susceptibility to NMDA-induced clonic seizures in mice without changes in adenosine A1 receptor number

1993 • 98 citations

Locomotor activity in mice during chronic treatment with caffeine and withdrawal

1993 • 98 citations

The Effect of Long Term Caffeine Treatment on Hypoxic-Ischemic Brain Damage in the Neonate

1995 • 94 citations

N-methyl-D-aspartate antagonists and working memory performance: Comparison with the effects of scopolamine, propranolol, diazepam, and phenylisopropyladenosine.

1991 • 85 citations

The effects of adenosine A3 receptor stimulation on seizures in mice

1995 • 84 citations

Caffeine treatment and withdrawal in mice: relationships between dosage, concentrations, locomotor activity and A1 adenosine receptor binding.

1993 • 83 citations

Effects of chronic administration of adenosine A1 receptor agonist and antagonist on spatial learning and memory

1993 • 79 citations

N6-cyclopentyladenosine impairs passive avoidance retention by selective action at A1 receptors

1991 • 77 citations

Protective effect of cyclohexyl adenosine in treatment of cerebral ischemia in gerbils

1989 • 76 citations

Effects of N6-cyclopentyl adenosine and 8-cyclopentyl-1,3-dipropylxanthine on induced seizures in mice

1993 • 72 citations

Chronic adenosine A1 receptor agonist and antagonist: effect on receptor density and induced seizures in mice

1994 • 62 citations

Selective A₁-Antagonists for Treatment of Cognitive Deficits

1991 • 58 citations

Caffeine, Coffee and Health

1994 • 53 citations

The role of adenosine receptors in the central action of caffeine.

1994 • 52 citations

Activation of adenosine A1 receptors underlies anticonvulsant effect of CGS21680

1994 • 51 citations

Caffeine cross-tolerance to selective dopamine D1 and D2 receptor agonists but not to their synergistic interaction

1994 • 51 citations

Increased expression of c-jun, junB, AP-1, and preproenkephalin mRNA in rat striatum following a single injection of caffeine

1995 • 50 citations

Effects of adenosine receptor agonists and antagonists on acquisition of passive avoidance learning

1994 • 48 citations

Cross-tolerance studies between caffeine and (−)-N6-(phenylisopropyl)-adenosine (PIA) in mice

1986 • 44 citations

Adenosine: a Prototherapeutic Concept in Neurodegeneration

1995 • 42 citations

Contrasting effects of adenosine A1 and A2 receptor ligands in different chemoconvulsive rodent models

1993 • 42 citations

Effects of chronic caffeine on adenosine, dopamine and acetylcholine systems in mice.

1994 • 39 citations

Repeated administration of selective adenosine A1 and A2 receptor agonists in the spontaneously hypertensive rat: tolerance develops to A1-mediated hemodynamic effects.

1994 • 33 citations

Development of tolerance to the antihypertensive effects of highly selective adenosine A2a agonists upon chronic administration.

1993 • 32 citations

Tolerance to oral and IP caffeine: Locomotor activity and pharmacokinetics

1994 • 32 citations

Temporal relationship between A1 adenosine receptor upregulation and alterations in bicuculline seizure susceptibility in rats

1989 • 21 citations

Effects of combinations of methylxanthines and adenosine analogs on locomotor activity in control and chronic caffeine‐treated mice

1993 • 19 citations

Action of caffeine, L-PIA and their combination of memory retention in the rat

1994 • 17 citations

Neuroprotective Agents

1999 • 14 citations

Effects of chronic administration of adenosine antagonists on adenosine A1 and A2a receptors in mouse brain.

1994 • 13 citations

Chronic theophylline prolongs the refractory period in amygdala‐kindled rats

1993 • 5 citations