Locomotor activity in mice during chronic treatment with caffeine and withdrawal

Adenosine receptors and behavioral actions of methylxanthines.

1981 • 705 citations

The pharmacology of caffeine

1987 • 219 citations

CNS stimulants: two distinct mechanisms of action for amphetamine-like drugs

1983 • 203 citations

Caffeine and theophylline analogues: Correlation of behavioral effects with activity as adenosine receptor antagonists and as phosphodiesterase inhibitors

1988 • 194 citations

Adenosine actions and adenosine receptors after 1 week treatment with caffeine

1982 • 174 citations

Chronic caffeine consumption increases the number of brain adenosine receptors

1983 • 147 citations

Both A₁ and A_2a Purine Receptors Regulate Striatal Acetylcholine Release

1990 • 139 citations

Characteristic behavioral alterations in rats induced by rolipram and other selective adenosine cyclic 3?,5?-monophosphate phosphodiesterase inhibitors

1982 • 138 citations

Interactions in the behavioral effects of methylxanthines and adenosine derivatives.

1983 • 128 citations

Central effects of adenosine analogs on locomotor activity in mice and antagonism of caffeine

1983 • 128 citations

Analogs of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors

1986 • 121 citations

Some effects of muscarinic cholinergic blocking drugs on behavior and the electrocorticogram

1964 • 116 citations

Role of adenosine receptors in caffeine tolerance.

1991 • 111 citations

Chronic caffeine ingestion sensitizes the A1 adenosine receptor-adenylate cyclase system in rat cerebral cortex.

1986 • 105 citations

Behavioral effects of A1- and A2-selective adenosine agonists and antagonists: evidence for synergism and antagonism.

1991 • 103 citations

Complete, reversible, drug-specific tolerance to stimulation of locomotor activity by caffeine

1983 • 98 citations

Tolerance to behavioral effects of caffeine in rats

1988 • 94 citations

Endothelin mobilizes Ca2+ from a caffeine- and ryanodine-insensitive intracellular pool in rat atrial cells.

1990 • 87 citations

Caffeine tolerance: Behavioral, electrophysiological and neurochemical evidence

1985 • 85 citations

Up-regulation of rat cortical adenosine receptors following chronic administration of theophylline

1982 • 80 citations

Upregulation of Adenosine Al Receptors and Forskolin Binding Sites Following Chronic Treatment with Caffeine or Carbamazepine: A Quantitative Autoradiographic Study

1989 • 73 citations

Behavioral characteristics of centrally administered adenosine analogs

1986 • 69 citations

The effect of cholinergic stimulation in the nucleus accumbens on locomotor behavior

1988 • 59 citations

Effect of caffeine on cocaine locomotor stimulant activity in rats

1986 • 55 citations

Effects of chronic administration of caffeine on adenosine A1 and A2 receptors in rat brain

1988 • 55 citations

Characterization of the locomotor depression produced by an A₂‐selective adenosine agonist

1990 • 52 citations

Behavioral effects of intrastriatal caffeine mediated by adenosinergic modulation of dopamine

1991 • 50 citations

Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine.

1990 • 47 citations

Cross-tolerance studies between caffeine and (−)-N6-(phenylisopropyl)-adenosine (PIA) in mice

1986 • 44 citations

Up-regulation of brain [3H]diazepam binding sites in chronic caffeine-treated rats

1984 • 43 citations

Caffeine inhibits inositol-trisphosphate-induced membrane potential oscillations inXenopusoocytes

1991 • 42 citations

Agonist derived molecular probes for A₂ adenosine receptors

1989 • 37 citations

Inhibition of acetylcholine turnover rate in rat hippocampus and cortex by intraventricular injection of adenosine analogs.

1982 • 35 citations

Preferential effects of caffeine on limbic and cortical dopamine systems

1988 • 32 citations

Tolerance and sensitization to chronic and subchronic oral caffeine: Effects of wheelrunning in rats

1990 • 31 citations

Caffeine pretreatment: Enhancement and attenuation of d-amphetamine-induced activity

1984 • 30 citations

The influence of caffeine on d-amphetamine- and apomorphine-induced stereotyped behavior

1974 • 29 citations

Antagonism of the behavioral effects of L-phenylisopropyladenosine (L-PIA) by caffeine and its metabolites

1984 • 26 citations

Caffeine potentiation of amphetamine: Implications for hyperkinesis therapy

1977 • 26 citations

Chronic caffeine treatment reduces caffeine but not adenosine effects on cortical acetylcholine release

1986 • 21 citations

Adenosine A_1‐receptor‐mediated inhibition of evoked acetylcholine release in the rat hippocampus does not depend on protein kinase C

1990 • 19 citations

Neurophysiological and pharmacodynamic studies on caffeine and on interactions between caffeine and nicotinic acid in the rat

1978 • 19 citations

Behavioral effects of caffeine, (-)N-((R)-1-methyl-2-phenylethyl)-adenosine (PIA), and their combination in the mouse

1985 • 18 citations

Caffeine withdrawal affects central adenosine receptors but not benzodiazepine receptors

1989 • 17 citations

Psychomotor-stimulant effects of 3-isobutyl-1-methylxanthine: Comparison with caffeine and 7-(2-chloroethyl) theophylline

1989 • 15 citations

Cross interaction between methamphetamine and scopolamine by means of ambulatory activity in mice.

1990 • 2 citations