A human RNA helicase-like protein, HRH1, facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

The HIV-1 Rev Activation Domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

1995 • 1,127 citations

SR proteins: a conserved family of pre-mRNA splicing factors.

1992 • 766 citations

Specific interactions between proteins implicated in splice site selection and regulated alternative splicing

1993 • 741 citations

Biochemical Mechanisms of Constitutive and Regulated Pre-mRNA Splicing

1991 • 708 citations

Protein–protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

1994 • 622 citations

Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF-4A.

1992 • 613 citations

Cloning and domain structure of the mammalian splicing factor U2AF

1992 • 566 citations

Regulation by HIV Rev depends upon recognition of splice sites

1989 • 517 citations

Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators

1991 • 508 citations

Messenger RNA Splicing in Yeast: Clues to Why the Spliceosome Is a Ribonucleoprotein

1991 • 433 citations

Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm

1989 • 417 citations

Monomethylated cap structures facilitate RNA export from the nucleus

1990 • 411 citations

Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene

1987 • 406 citations

Primary structure of the human splicing factor asf reveals similarities with drosophila regulators

1991 • 357 citations

Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomes

1991 • 354 citations

PRP16 is an RNA-dependent ATPase that interacts transiently with the spliceosome

1991 • 329 citations

Mechanism of action of regulatory proteins encoded by complex retroviruses

1992 • 299 citations

The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein

1988 • 266 citations

Isolation of a Complementary DNA that Encodes the Mammalian Splicing Factor SC35

1992 • 244 citations

Functional analysis of pre-mRNA splicing factor SF2/ASF structural domains.

1993 • 243 citations

Cloning of the human cDNA for the U1 RNA-associated 70K protein.

1986 • 235 citations

Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing

1991 • 224 citations

Pre-mRNA Splicing in Yeast

1989 • 209 citations

Functional domains of the human splicing factor ASF/SF2.

1993 • 188 citations

The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2

1994 • 182 citations

RNA Export

1995 • 181 citations

RNA helicases: modulators of RNA structure

1994 • 169 citations

The purified yeast pre-mRNA splicing factor PRP2 is an RNA-dependent NTPase.

1992 • 149 citations

Developmental expression of a regulatory gene is programmed at the level of splicing.

1987 • 143 citations

Splicing of yeast nuclear pre-mRNA in vitro requires a functional 40S spliceosome and several extrinsic factors.

1987 • 137 citations

Preferential excision of the 5' proximal intron from mRNA precursors with two introns as mediated by the cap structure.

1987 • 114 citations

A dominant negative mutation in the conserved RNA helicase motif ‘SAT’ causes splicing factor PRP2 to stall in spliceosomes.

1994 • 92 citations

Identification of a putative RNA helicase (HRH1), a human homolog of yeast Prp22.

1994 • 75 citations

[30] analysis of splicing complexes and small nuclear ribonucleoprotein particles by native gel electrophoresis

1989 • 64 citations

Cloning of a complementary DNA encoding an 80 kilodalton nuclear cap binding protein

1994 • 38 citations