Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Cyclin synthesis drives the early embryonic cell cycle

1989 • 1,223 citations

The hepatitis B virus

1985 • 1,219 citations

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

1989 • 1,031 citations

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

1989 • 990 citations

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

1989 • 931 citations

Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

1989 • 920 citations

Activation of cdc2 protein kinase during mitosis in human cells: Cell cycle-dependent phosphorylation and subunit rearrangement

1988 • 786 citations

cdc2 protein kinase is complexed with both cyclin A and B: Evidence for proteolytic inactivation of MPF

1989 • 666 citations

Presence of integrated hepatitis B virus DNA sequences in cellular DNA of human hepatocellular carcinoma

1980 • 610 citations

MPF from starfish oocytes at first meiotic metaphase is a heterodimer containing one molecule of cdc2 and one molecule of cyclin B.

1989 • 550 citations

The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes

1986 • 534 citations

Reversible tyrosine phosphorylation of cdc2: Dephosphorylation accompanies activation during entry into mitosis

1989 • 453 citations

Translation of cyclin mRNA is necessary for extracts of activated Xenopus eggs to enter mitosis

1989 • 438 citations

Expression and function of Drosophila cyclin a during embryonic cell cycle progression

1989 • 399 citations

Hepatitis B virus DNA integration in a sequence homologous to v-erb-A and steroid receptor genes in a hepatocellular carcinoma

1986 • 399 citations

Purified maturation promoting factor phosphorylates pp60c-src at the sites phosphorylated during fibroblast mitosis

1989 • 319 citations

Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinase.

1989 • 308 citations

A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma

1987 • 282 citations

Relationship Between Hepatocellular Carcinoma and Cirrhosis

1984 • 264 citations

A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells

1989 • 262 citations

Phosphorylation of large tumour antigen by cdc2 stimulates SV40 DNA replication

1989 • 242 citations

The role of cyclin B in meiosis I.

1989 • 241 citations

Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase

1989 • 239 citations

Molecular cloning and characterization of the mRNA for cyclin from sea urchin eggs.

1987 • 220 citations

The mode of hepatitis B virus DNA integration in chromosomes of human hepatocellular carcinoma.

1987 • 204 citations

Hepatocellular Carcinoma and Hepatitis B Virus

1984 • 202 citations

Deletion in Chromosome 11p Associated with a Hepatitis B Integration Site in Hepatocellular Carcinoma

1985 • 199 citations

Activation of c-myc by woodchuck hepatitis virus insertion in hepatocellular carcinoma

1988 • 192 citations

Cyclin synthesis, modification and destruction during meiotic maturation of the starfish oocyte

1987 • 176 citations

Activation of human CDC2 protein as a histone H1 kinase is associated with complex formation with the p62 subunit.

1989 • 148 citations

Multiple integration site of hepatitis B virus DNA in hepatocellular carcinoma and chronic active hepatitis tissues from children

1987 • 118 citations

Chromosomal translocation and inverted duplication associated with integrated hepatitis B virus in hepatocellular carcinomas

1987 • 113 citations

Relative risks of death due to liver disease among Japanese male adults having various statuses for hepatitis B s and e antigen/antibody in serum: A prospective study

1988 • 106 citations

Features of two hepatitis B virus (HBV) DNA integrations suggest mechanisms of HBV integration

1989 • 80 citations

Rearrangement of a common cellular DNA domain on chromosome 4 in human primary liver tumors

1988 • 52 citations

Regional mapping to 4q32.1 by in situ hybridization of a DNA domain rearranged in human liver cancer

1988 • 22 citations