Multiple integration site of hepatitis B virus DNA in hepatocellular carcinoma and chronic active hepatitis tissues from children

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

HEPATOCELLULAR CARCINOMA AND HEPATITIS B VIRUS

1981 • 2,891 citations

Presence of integrated hepatitis B virus DNA sequences in cellular DNA of human hepatocellular carcinoma

1980 • 610 citations

Hepatocellular carcinoma and the hepatitis B virus: evidence for a causal association.

1978 • 588 citations

Tbe complete nudeotide sequences of the cloned hepatitis B vims DNA; subtype adr and adw

1983 • 426 citations

State of hepatitis B virus DNA in hepatocytes of patients with hepatitis B surface antigen-positive and -negative liver diseases.

1981 • 351 citations

DETECTION OF HEPATITIS B VIRUS DNA IN LIVER AND SERUM: A DIRECT APPRAISAL OF THE CHRONIC CARRIER STATE

1981 • 333 citations

Biochemical and Genetic Evidence for the Hepatitis B Virus Replication Strategy

1986 • 296 citations

A human hepatitis B viral enhancer element.

1985 • 286 citations

Identification of integrated hepatitis B virus DNA sequences in human hepatocellular carcinomas

1981 • 217 citations

Complete nucleotide sequence of hepatitis B virus DNA of subtype adr and its conserved gene organization

1984 • 196 citations

State of hepatitis B viral DNA in a human hepatoma cell line

1980 • 164 citations

Specific hepatitis B virus integration in hepatocellular carcinoma DNA through a viral 11-base-pair direct repeat.

1984 • 156 citations

Transcripts and the putative RNA pregenome of duck hepatitis B virus: Implications for reverse transcription

1985 • 143 citations

Cloning and structural analysis of integrated woodchuck hepatitis virus sequences from hepatocellular carcinomas of woodchucks

1982 • 125 citations

Integration of hepatitis B virus DNA: Evidence for integration in the single-stranded gap

1983 • 123 citations

Hepadnavirus infection of peripheral blood lymphocytes in vivo: woodchuck and chimpanzee models of viral hepatitis

1986 • 120 citations

Sequence of hepatitis B virus DNA incorporated into the genome of a human hepatoma cell line

1985 • 113 citations

Hepatitis B virus integration in hepatocellular carcinoma DNA: duplication of cellular flanking sequences at the integration site.

1985 • 112 citations

Characterization of integrated hepatitis B viral DNA cloned from a human hepatoma and the hepatoma-derived cell line PLC/PRF/5.

1983 • 98 citations

Inversely repeating integrated hepatitis B virus DNA and cellular flanking sequences in the human hepatoma-derived cell line huSP.

1985 • 86 citations

Polypeptides of hepatitis B virus surface antigen produced by a hepatoma cell line

1979 • 80 citations

Cloning and structural analysis of integrated woodchuck hepatitis virus sequences from a chronically infected liver

1984 • 61 citations

The genetic organization of integrated hepatitis B virus DNA in the human hepatoma cell line PLC/PRF/5

1984 • 51 citations

Direct evidence for the expression of integrated hepatitis B virus DNA in human hepatoma tissue.

1984 • 16 citations