Translation of cyclin mRNA is necessary for extracts of activated Xenopus eggs to enter mitosis

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

DNA cloning : a practical approach

1985 • 2,302 citations

DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.

1987 • 2,266 citations

Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes

1971 • 1,553 citations

Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

1983 • 1,506 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

1987 • 1,153 citations

Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog

1987 • 1,004 citations

cdc25+ functions as an inducer in the mitotic control of fission yeast

1986 • 973 citations

Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe

1976 • 906 citations

Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+

1988 • 885 citations

The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis

1988 • 829 citations

An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences

1982 • 801 citations

Processing of Adenovirus 2-Induced Proteins

1973 • 762 citations

[25] In vitro RNA synthesis with SP6 RNA polymerase

1987 • 732 citations

Purification of maturation-promoting factor, an intracellular regulator of early mitotic events.

1988 • 640 citations

Formation in Vitro of Sperm Pronuclei and Mitotic Chromosomes Induced by Amphibian Ooplasmic Components

1983 • 630 citations

Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs

1986 • 622 citations

A role for the nuclear envelope in controlling DNA replication within the cell cycle

1988 • 605 citations

Cell cycle dynamics of an M-phase-specific cytoplasmic factor in Xenopus laevis oocytes and eggs.

1984 • 575 citations

[4] Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA

1983 • 547 citations

cdc2 is a component of the M phase-specific histone H1 kinase: Evidence for identity with MPF

1988 • 535 citations

The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes

1986 • 534 citations

The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation

1986 • 502 citations

Isolation and Identification of Meiosis Inducing Substance in Starfish Asterias amurensis

1969 • 455 citations

The interaction of steroids with Rana pipiens oocytes in the induction of maturation

1971 • 400 citations

Site specific enzymatic cleavage of RNA

1979 • 400 citations

Regulation of the cell cycle during early Xenopus development

1984 • 376 citations

Regulated replication of DNA microinjected into eggs of Xenopus laevis

1980 • 362 citations

The mitotic inducer nim1+ functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis

1987 • 334 citations

Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2+

1988 • 314 citations

Effects of cycloheximide on a cytoplasmic factor initiating meiotic maturation in Xenopus oocytes

1975 • 294 citations

[7] Random cloning and sequencing by the M13/dideoxynucleotide chain termination method

1987 • 292 citations

Changes in protein phosphorylation accompanying maturation of Xenopus laevis oocytes

1977 • 269 citations

Genetics of polyploid Xenopus

1986 • 257 citations

Roles of cytosol and cytoplasmic particles in nuclear envelope assembly and sperm pronuclear formation in cell-free preparations from amphibian eggs.

1984 • 254 citations

Mitotic factors from mammalian cells induce germinal vesicle breakdown and chromosome condensation in amphibian oocytes.

1979 • 252 citations

The use of single-stranded DNA and RNase H to promote quantitative ‘hybrid arrest of translation’ of mRNA/DNA hybrids in reticulocyte lysate cell-free translations

1986 • 245 citations

Involvement of cdc13+ in mitotic control in Schizosaccharomyces pombe: possible interaction of the gene product with microtubules.

1988 • 234 citations

Selective elimination of mRNAs in vivo: complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity.

1987 • 225 citations

Cytoplasmic factor responsible for germinal vesicle breakdown and meiotic maturation in starfish oocyte

1976 • 221 citations

Molecular cloning and characterization of the mRNA for cyclin from sea urchin eggs.

1987 • 220 citations

The cyclic behavior of a cytoplasmic factor controlling nuclear membrane breakdown.

1978 • 216 citations

Regulation of MPF activity in vitro

1988 • 209 citations

Generality of the action of various maturation-promoting factors

1982 • 195 citations

Nucleic Acid Hybridisation — A Practical Approach

1986 • 184 citations

Interaction between cdc13+ and cdc2+ in the control of mitosis in fission yeast; dissociation of the G1 and G2 roles of the cdc2+ protein kinase.

1987 • 177 citations

Cyclin synthesis, modification and destruction during meiotic maturation of the starfish oocyte

1987 • 176 citations

Maturation-promoting factor induces nuclear envelope breakdown in cycloheximide-arrested embryos of Xenopus laevis.

1983 • 169 citations

Cell cycle control genes in fission yeast and mammalian cells

1988 • 168 citations

Maturation and Fertilization in Starfish Oocytes

1984 • 163 citations

The effect of puromycin on protein metabolism and cell division in fertilized sea urchin eggs

1961 • 160 citations

Activity of the maturation-promoting factor and the extent of protein phosphorylation oscillate simultaneously during meiotic maturation of starfish oocytes

1983 • 137 citations

Antisense oligonucleotide-directed cleavage of mRNA in Xenopus oocytes and eggs.

1988 • 136 citations

Periodic DNA synthesis in cell-free extracts of Xenopus eggs.

1987 • 127 citations

Accumulation of individual pA+ RNAs during oogenesis of Xenopus laevis

1980 • 119 citations

Phosphorylation changes associated with the early cell cycle in Xenopus eggs

1987 • 118 citations

The timing of early developmental events in Xenopus

1985 • 114 citations

The timing of synthesis of proteins required for mitosis in the cell cycle of the sea urchin embryo*1

1983 • 111 citations

Role of protein synthesis and proteases in production and inactivation of maturation-promoting activity during meiotic maturation of starfish oocytes

1985 • 104 citations

Molecular Regulation of Nuclear Events in Mitosis and Meiosis

1987 • 99 citations

Synthesis of RNA and protein required for the mitosis of mammalian cells

1964 • 92 citations

Metaphase protein phosphorylation in Xenopus laevis eggs.

1987 • 90 citations

Protein phosphatase-1 is involved in Xenopus oocyte maturation

1981 • 86 citations

An M-phase-specific protein kinase of Xenopus oocytes: Partial purification and possible mechanism of its periodic activation

1988 • 85 citations

Old and new protein in the formation of the mitotic apparatus in cleaving sea urchin eggs

1967 • 79 citations

Mitosis-inducing factors are present in a latent form during interphase in the Xenopus embryo.

1988 • 69 citations

Action of actinomycin and puromycin upon frog oocyte maturation

1966 • 68 citations

Development of Cytoplasmic Activities That Control Chromosome Cycles during Maturation of Amphibian Oocytes

1987 • 43 citations

Maturation promoting factor and cell cycle regulation

1985 • 42 citations

Role of Protein Phosphorylation in Xenopus Oocyte Meiotic Maturation

1987 • 26 citations

A mitotic inducer matures

1988 • 15 citations

DNA synthesis in the first cell cycle of Xenopus

1983 • 3 citations