Role of Dynactin in Endocytic Traffic: Effects of Dynamitin Overexpression and Colocalization with CLIP-170

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

ENDOCYTOSIS AND MOLECULAR SORTING

1996 • 1,537 citations

ER-to-Golgi transport visualized in living cells

1997 • 1,169 citations

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

1998 • 1,101 citations

Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein.

1996 • 849 citations

Isolation of Monoclonal Antibodies Specific for Human c-myc Proto-Oncogene Product

1985 • 788 citations

A lipid associated with the antiphospholipid syndrome regulates endosome structure and function

1998 • 774 citations

EEA1, an Early Endosome-Associated Protein.

1995 • 706 citations

Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin.

1981 • 699 citations

Dynactin increases the processivity of the cytoplasmic dynein motor

1999 • 660 citations

Overexpression of the Dynamitin (p50) Subunit of the Dynactin Complex Disrupts Dynein-dependent Maintenance of Membrane Organelle Distribution

1997 • 652 citations

Membrane transport in the endocytic pathway

1995 • 644 citations

Membrane flow during pinocytosis. A stereologic analysis.

1976 • 639 citations

Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis.

1996 • 634 citations

Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro.

1989 • 588 citations

Visualization of ER-to-Golgi Transport in Living Cells Reveals a Sequential Mode of Action for COPII and COPI

1997 • 510 citations

Translocation and clustering of endosomes and lysosomes depends on microtubules.

1987 • 498 citations

Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein.

1991 • 482 citations

A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor.

1991 • 478 citations

The Receptor Recycling Pathway Contains Two Distinct Populations of Early Endosomes with Different Sorting Functions

1999 • 446 citations

Exit of newly synthesized membrane proteins from the trans cisterna of the Golgi complex to the plasma membrane.

1985 • 415 citations

Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa.

1993 • 413 citations

Cytoplasmic dynein-dependent vesicular transport from early to late endosomes [published erratum appears in J Cell Biol 1994 Feb;124(3):397]

1993 • 408 citations

Sequential coupling between COPII and COPI vesicle coats in endoplasmic reticulum to Golgi transport.

1995 • 407 citations

CLIP-170 Highlights Growing Microtubule Ends In Vivo

1999 • 389 citations

Developmental Regulation of Vesicle Transport in Drosophila Embryos: Forces and Kinetics

1998 • 389 citations

Microinjected antibodies against the cytoplasmic domain of vesicular stomatitis virus glycoprotein block its transport to the cell surface.

1986 • 374 citations

CLIP-170 links endocytic vesicles to microtubules

1992 • 367 citations

Golgi Vesiculation and Lysosome Dispersion in Cells Lacking Cytoplasmic Dynein

1998 • 363 citations

Dynactin Is Required for Microtubule Anchoring at Centrosomes

1999 • 354 citations

Rab4 and cellubrevin define different early endosome populations on the pathway of transferrin receptor recycling.

1996 • 338 citations

β-COP is essential for biosynthetic membrane transport from the endoplasmic reticulum to the Golgi complex in vivo

1993 • 336 citations

Cytoplasmic dynein plays a role in mammalian mitotic spindle formation.

1993 • 335 citations

The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1).

1995 • 307 citations

Microtubule- and motor-dependent fusion in vitro between apical and basolateral endocytic vesicles from MDCK cells

1990 • 299 citations

Cytoplasmic coat proteins involved in endosome function

1995 • 290 citations

Targeting of Motor Proteins

1996 • 278 citations

Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin.

1994 • 275 citations

Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles.

1996 • 228 citations

Colocalization of cytoplasmic dynein with dynactin and CLIP-170 at microtubule distal ends

1999 • 215 citations

Non-bilayer lipids and biological fusion intermediates

1996 • 211 citations

Passage of an integral membrane protein, the vesicular stomatitis virus glycoprotein, through the Golgi apparatus en route to the plasma membrane.

1981 • 209 citations

Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.

1996 • 203 citations

Motors and membrane traffic

1997 • 187 citations

Analysis of Dynactin Subcomplexes Reveals a Novel Actin-Related Protein Associated with the Arp1 Minifilament Pointed End

1999 • 177 citations

The visualization of fluorescent proteins in living cells by video intensification microscopy (VIM)

1978 • 169 citations

Evidence for a Role of CLIP-170 in the Establishment of Metaphase Chromosome Alignment

1998 • 149 citations

Dynamic measurement of the pH of the Golgi complex in living cells using retrograde transport of the verotoxin receptor.

1996 • 148 citations

The Role of the Dynactin Complex in Intracellular Motility

1998 • 145 citations

Inhibition of Endosome Function in CHO Cells Bearing a Temperature-sensitive Defect in the Coatomer (COPI) Component ε-COP

1997 • 138 citations

Characterization of a 50-kDa polypeptide in cytoplasmic dynein preparations reveals a complex with p150GLUED and a novel actin

1993 • 120 citations

Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells.

1995 • 116 citations

Molecular characterization of two functional domains of CLIP-170 in vivo

1994 • 110 citations

SFV infection in CHO cells: cell-type specific restrictions to productive virus entry at the cell surface

1997 • 108 citations

Identification of a novel nucleotide-sensitive microtubule-binding protein in HeLa cells.

1990 • 106 citations

Microtubule-based membrane movement

1998 • 105 citations

Binding of pp170 to microtubules is regulated by phosphorylation.

1991 • 101 citations

CLIPs for organellemicrotubule interactions

1996 • 96 citations

The mechanism and regulation of fast axonal transport

1989 • 90 citations

Overexpression of MAP4 inhibits organelle motility and trafficking in vivo

1997 • 85 citations

Regulation of vesicle transport in CV-1 cells and extracts

1993 • 85 citations

Isolation of a temperature‐sensitive variant Chinese hamster ovary cell line with a morphologically altered endocytic recycling compartment

1993 • 73 citations

Chapter 7 Recombinant p50/Dynamitin as a Tool to Examine the Role of Dynactin in Intracellular Processes

1998 • 70 citations

Motor proteins: A dynamic duo

1996 • 69 citations

A novel cytoplasmic dynein heavy chain: expression of DHC1b in mammalian ciliated epithelial cells

1996 • 64 citations

The isolation of vascular endothelial cell lines with altered cell surface and platelet-binding properties

1978 • 57 citations

Structure and function of dynactin

1996 • 53 citations

Kinetics of α₂‐macroglobulin endocytosis and degradation in mutant and wild‐type Chinese hamster ovary cells

1989 • 40 citations

A protein-specific monoclonal antibody to rat liver beta 1-->4 galactosyltransferase and its application to immunohistochemistry.

1994 • 39 citations