Synthesis of 3-Substituted Benzamides and 5-Substituted Isoquinolin-1(2H)-ones and Preliminary Evaluation as Inhibitors of Poly(ADP-ribose)polymerase (PARP)

.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines

1969 • 2,435 citations

The crystal structure of diphtheria toxin

1992 • 663 citations

Baker's Yeast as a Reagent in Organic Synthesis

1990 • 528 citations

Novel inhibitors of poly(ADP-ribose) synthetase

1980 • 519 citations

Structure of the catalytic fragment of poly(AD-ribose) polymerase from chicken.

1996 • 234 citations

ADP-Ribose in DNA Repair: A New Component of DNA Excision Repair

1984 • 226 citations

Crystal Structure of Diphtheria Toxin Bound to Nicotinamide Adenine Dinucleotide

1996 • 200 citations

Asymmetric synthesis using chirally modified borohydrides. Part 3. Enantioselective reduction of ketones and oxime ethers with reagents prepared from borane and chiral amino alcohols

1985 • 189 citations

Refined structure of monomelic diphtheria toxin at 2.3 Å resolution

1994 • 172 citations

Refined structure of dimeric diphtheria toxin at 2.0 Å resolution

1994 • 157 citations

Potentiation of temozolomide-induced cytotoxicity: a comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors

1995 • 131 citations

3-aminobenzamide and/or O6-benzylguanine evaluated as an adjuvant to temozolomide or BCNU treatment in cell lines of variable mismatch repair status and O6-alkylguanine-DNA alkyltransferase activity

1996 • 121 citations

Molecular mechanisms in the control of translation by hormones and growth factors

1994 • 101 citations

Selective reductions. 40. A critical examination of the relative effectiveness of various reducing agents for the asymmetric reduction of different classes of ketones

1987 • 98 citations

Direct α-hydroxylation of ketones under acidic conditions using [bis (trifluoroacetoxy)] iodobenzene

1992 • 95 citations

The role of inhibitors of poly(ADP-ribose) polymerase as resistance-modifying agents in cancer therapy

1995 • 92 citations

Synthesis and cytotoxic activity of C-glycosidic nicotinamide riboside analogs

1992 • 88 citations

Optisch aktive C₅‐Bausteine zur Synthese von natürlich vorkommenden Terpenen

1983 • 70 citations

Selective palladium-catalyzed vinylic substitutions with bromoiodo aromatics

1979 • 69 citations

Production of 2-methyl-4(3H)-quinazolinone, an inhibitor of poly(ADP-ribose) synthetase, by bacterium.

1991 • 67 citations

Asymmetric sharpless epoxidation of divinylcarbinol. Erythro-D- and -L-4-pentenitols by hydrolysis of regioisomeric epoxy-4-pentenols

1991 • 64 citations

Inhibitors of poly(ADP-ribose) synthesis enhance X-ray killing of log-phase Chinese hamster cells.

1984 • 54 citations

Stereochemical control of bakers' yeast mediated reduction of a protected 2-hydroxy ketone

1988 • 53 citations

The stereospecific asymmetric reduction of functionalised ketones

1975 • 49 citations

810. Studies of the amino-isoquinolines, -cinnolines, and -quinazolines

1956 • 47 citations

Radiosensitization of Human Fibroblasts by 3-Aminobenzamide: An Inhibitor of Poly(ADP-Ribosylation)

1985 • 46 citations

Crystal Structure of Nucleotide-Free Diphtheria Toxin^,

1997 • 45 citations

5-Nitrofuran-2-ylmethyl group as a potential bioreductively activated pro-drug system

1997 • 39 citations

Inhibitors of Poly(ADP-Ribose) Synthesis Enhance X-Ray Killing of Log-Phase Chinese Hamster Cells

1984 • 37 citations

ASYMMETRIC REDUCTION OF PROCHIRAL CYCLIC KETONES WITH LITHIUM ALUMINUM HYDRIDE PARTIALLY DECOMPOSED BY (1R,2S)-(−)-N-METHYLEPHEDRINE AND 2-ALKYLAMINOPYRIDINE

1984 • 36 citations

Baker's yeast-mediated preparation of optically active aryl alcohols and diols for the synthesis of chiral hydroxy acids

1990 • 35 citations

Derivatives of Hemimellitic Acid. A Synthesis of Erythrocentaurin¹

1964 • 32 citations

DNA Strand Break-Mediated Partitioning of Poly(ADP-Ribose) Polymerase Function

1994 • 32 citations

Potentiation of the antitumor activity of cisplatin in mice by 3-aminobenzamide and nicotinamide

1988 • 31 citations

Inhibition of Gamma-Ray Dose-Rate Effects by D 2 O and Inhibitors of Poly(ADP-Ribose) Synthetase in Cultured Mammalian L5178Y Cells

1984 • 30 citations

Baker's yeast-mediated reduction of α-hydroxy ketones and derivatives: The steric course of the biotransformation

1994 • 27 citations

Notes - Carbonation of Lithium Derivatives of Certain Quinolines and Isoquinolines

1957 • 27 citations

Enhancement of alkylating agent activity in vitro by PD 128763, a potent poly(ADP-ribose) synthetase inhibitor

1992 • 26 citations

The synthesis of quinoline‐ and isoquinolinecarboxaldehydes

1969 • 25 citations

Über Derivate des Veratrols

1918 • 17 citations

Facile Synthesis of Glycol Metabolites of Phenethylamine Drugs1

1986 • 14 citations

Cellular mono(ADP‐ribosyl) transferase inhibits protein synthesis

1991 • 13 citations

SYNTHESIS OF SOME NOVEL α,β-ETHYLENIC SULFONES

1991 • 7 citations

Analogues of benzamide as poly(ADP-ribose)transferase inhibitors: A study on structure activity relationships

1988 • 5 citations