Regulation of Endocytosis of Activin Type II Receptors by a Novel PDZ Protein through Ral/Ral-binding Protein 1-dependent Pathway

Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid

1986 • 1,148 citations

Pituitary FSH is released by a heterodimer of the β-subunits from the two forms of inhibin

1986 • 1,071 citations

Expression cloning of an activin receptor, a predicted transmembrane serine kinase

1991 • 760 citations

A kinase-regulated PDZ-domain interaction controls endocytic sorting of the β2-adrenergic receptor

1999 • 673 citations

Gradient Formation of the TGF-β Homolog Dpp

2000 • 606 citations

Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis

1998 • 576 citations

Identification and Functional Characterization of a Smad Binding Element (SBE) in the JunB Promoter That Acts as a Transforming Growth Factor-β, Activin, and Bone Morphogenetic Protein-inducible Enhancer

1998 • 562 citations

Signaling of transforming growth factor‐β family members through Smad proteins

2000 • 530 citations

GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex.

1992 • 497 citations

Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors

1992 • 495 citations

Interactions of the Low Density Lipoprotein Receptor Gene Family with Cytosolic Adaptor and Scaffold Proteins Suggest Diverse Biological Functions in Cellular Communication and Signal Transduction

2000 • 458 citations

Regulation of receptor-mediated endocytosis by Rho and Rac

1996 • 386 citations

Cerebellar Long-Term Depression Requires PKC-Regulated Interactions between GluR2/3 and PDZ Domain–Containing Proteins

2000 • 381 citations

Mesodermal induction in early amphibian embryos by activin A (erythroid differentiation factor)

1990 • 357 citations

Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation.

1996 • 335 citations

The zebrafish Nodal signal Squint functions as a morphogen

2001 • 328 citations

Activin signalling and response to a morphogen gradient

1994 • 328 citations

Activation of Signalling by the Activin Receptor Complex

1996 • 317 citations

Identification and Characterization of Ral-Binding Protein 1, a Potential Downstream Target of Ral GTPases

1995 • 304 citations

Rho: theme and variations

1996 • 290 citations

Importance of FSH-releasing protein and inhibin in erythrodifferentiation

1987 • 275 citations

Activin Receptors and Cellular Signaling by the Receptor Serine Kinase Family

1994 • 259 citations

Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors

1999 • 232 citations

Evidence for a Ras/Ral signaling cascade

1996 • 214 citations

Regulated Endocytic Routing Modulates Wingless Signaling in Drosophila Embryos

2001 • 211 citations

The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors

1998 • 205 citations

The types II and III transforming growth factor-beta receptors form homo-oligomers.

1994 • 199 citations

The Type II Activin Receptors Are Essential for Egg Cylinder Growth, Gastrulation, and Rostral Head Development in Mice

1999 • 192 citations

Shaping Morphogen Gradients

2001 • 169 citations

β1-Adrenergic Receptor Association with PSD-95

2000 • 166 citations

Activation of the Small GTPase Ral in Platelets

1998 • 144 citations

Identification and Characterization of a Novel Protein Interacting with Ral-binding Protein 1, a Putative Effector Protein of Ral

1998 • 143 citations

Sorting Nexin 6, a Novel SNX, Interacts with the Transforming Growth Factor-β Family of Receptor Serine-Threonine Kinases

2001 • 130 citations

Bovine bone activin enhances bone morphogenetic protein-induced ectopic bone formation.

1992 • 124 citations

Association and Colocalization of Eps15 with Adaptor Protein-2 and Clathrin

1997 • 124 citations

Activin has direct long-range signalling activity and can form a concentration gradient by diffusion

1997 • 107 citations

Formation and activation by phosphorylation of activin receptor complexes.

1996 • 97 citations

Identification and Characterization of a PDZ Protein That Interacts with Activin Type II Receptors

2000 • 96 citations

A single internalization signal from the di-leucine family is critical for constitutive endocytosis of the type II TGF-β receptor

2001 • 94 citations

Transforming Growth Factor-β Receptor-associated Protein 1 Is a Smad4 Chaperone

2001 • 93 citations

Characterization of type II activin receptors. Binding, processing, and phosphorylation.

1993 • 83 citations

Epsin binds to the EH domain of POB1 and regulates receptor-mediated endocytosis

1999 • 82 citations

Activin exerts a neurotrophic effect on cultured hippocampal neurons

1997 • 81 citations

Ras-independent activation of Ral by a Ca2+-dependent pathway

1998 • 79 citations

Identification of Syntenin as a Protein of the Apical Early Endocytic Compartment in Madin-Darby Canine Kidney Cells

1999 • 76 citations

Colocalization of Ras and Ral on the membrane is required for Ras-dependent Ral activation through Ral GDP dissociation stimulator

1997 • 67 citations

Inactivation of activin-dependent transcription by kinase-deficient activin receptors.

1995 • 65 citations

Synergistic activation of c-fos promoter activity by Raf and Ral GDP dissociation stimulator

1997 • 63 citations

Embryonic expression and functional analysis of a Xenopus activin receptor

1992 • 63 citations

Distinct Endocytic Responses of Heteromeric and Homomeric Transforming Growth Factor β Receptors

1997 • 60 citations

Heteromeric and Homomeric Transforming Growth Factor-β Receptors Show Distinct Signaling and Endocytic Responses in Epithelial Cells

1998 • 50 citations

Activin A increases intracellular free calcium concentrations in rat pancreatic islets

1993 • 34 citations

The post‐translational modifications of Ral and Rac1 are important for the action of Ral‐binding protein 1, a putative effector protein of Ral

1997 • 31 citations

Modulation of adenosine triphosphate-sensitive potassium channel and voltage-dependent calcium channel by activin A in HIT-T15 cells.

1995 • 29 citations

Identification of a Novel Type II Activin Receptor, Type IIA-N, Induced during the Neural Differentiation of Murine P19 Embryonal Carcinoma Cells

1998 • 24 citations

Bovine Activin Receptor Type IIB Messenger Ribonucleic Acid Displays Alternative Splicing Involving a Sequence Homologous to Src-Homology 3 domain Binding Sites¹

1997 • 18 citations

Effects of activin A and somatostatin on intact FSH secretion and intracellular Ca2+ concentration in human FSH-secreting pituitary adenoma cells

1992 • 17 citations