Expression of the Type I Diabetes-associated Gene LRP5 in Macrophages, Vitamin A System Cells, and the Islets of Langerhans Suggests Multiple Potential Roles in Diabetes

A genome-wide search for human type 1 diabetes susceptibility genes

1994 • 1,294 citations

Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2

1999 • 1,231 citations

STRUCTURES AND FUNCTIONS OF MULTILIGAND LIPOPROTEIN RECEPTORS: Macrophage Scavenger Receptors and LDL Receptor-Related Protein (LRP)

1994 • 1,175 citations

The Retina: An Approachable Part of the Brain

1989 • 1,120 citations

Characterization of the human cysteinyl leukotriene CysLT1 receptor

1999 • 960 citations

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

1994 • 743 citations

The Nonobese Diabetic Mouse as a Model of Autoimmune Diabetes: Immune Dysregulation Gets the NOD

1997 • 685 citations

Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli

1996 • 655 citations

Vitamin A in Health and Disease

1994 • 602 citations

Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome llq

1994 • 397 citations

Improved method for obtaining 3-microns cryosections for immunocytochemistry.

1990 • 314 citations

LDL receptor‐related protein: a multiligand receptor for lipoprotein and proteinase catabolism

1995 • 272 citations

Analysis of Lipid Deposits Extracted From Human Macular and Peripheral Bruch's Membrane

1994 • 254 citations

Evidence for an Essential Role of Megalin in Transepithelial Transport of Retinol

1999 • 238 citations

Histology for Pathologists

1999 • 235 citations

Lipoprotein receptors: new roles for ancient proteins

1999 • 218 citations

Cloning of a novel member of the low-density lipoprotein receptor family

1998 • 217 citations

Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasis.

1996 • 211 citations

Isolation and Characterization ofLRP6,a Novel Member of the Low Density Lipoprotein Receptor Gene Family

1998 • 207 citations

Receptors of the low density lipoprotein (LDL) receptor family in man. Multiple functions of the large family members via interaction with complex ligands.

1998 • 183 citations

Islet-Specific Th1, But Not Th2, Cells Secrete Multiple Chemokines and Promote Rapid Induction of Autoimmune Diabetes

1999 • 181 citations

Potential Role of Resident Islet Macrophage Activation in the Initiation of Autoimmune Diabetes

1998 • 155 citations

The Retina: An Approachable Part of the Brain

1988 • 144 citations

From genome to aetiology in a multifactorial disease, type 1 diabetes

1999 • 143 citations

Storage of vitamin A in extrahepatic stellate cells in normal rats

1997 • 139 citations

Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8

1996 • 129 citations

Comparative genetics of type 1 diabetes and autoimmune disease: common loci, common pathways?

1999 • 128 citations

I-E+ nonobese diabetic mice develop insulitis and diabetes.

1993 • 128 citations

A New Low Density Lipoprotein Receptor Related Protein, LRP5, Is Expressed in Hepatocytes and Adrenal Cortex, and Recognizes Apolipoprotein E

1998 • 114 citations

Vitamin A homeostasis and diabetes mellitus

1997 • 85 citations

The vitamin A-storing cells in the human and rat pancreas.

1990 • 82 citations

Genetic association studies between Alzheimer's disease and two polymorphisms in the low density lipoprotein receptor-related protein gene

1998 • 80 citations

The hepatic perisinusoidal stellate cell.

1997 • 79 citations

Overview of vitamin A metabolism and function.

1994 • 72 citations

Molecular Cloning and Characterization of LR3, a Novel LDL Receptor Family Protein with Mitogenic Activity

1998 • 69 citations

Fine Mapping of the Diabetes-Susceptibility Locus, on Chromosome 11q13

1998 • 58 citations

Chromosomal Localization of Human Genes for the LDL Receptor Family Member Glycoprotein 330 (LRP2) and Its Associated Protein RAP (LRPAP1)

1994 • 52 citations

Molecular mechanisms in the reversible regulation of morphology, proliferation and collagen metabolism in hepatic stellate cells by the three‐dimensional structure of the extracellular matrix

1998 • 50 citations

Vitamin A status affects the development of diabetes and insulitis in BB rats

1996 • 27 citations

Macrophages and antioxidant status in the NOD mouse pancreas

1998 • 12 citations