Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasis.
Data up to Jan 2025
Total Citations Per Year
Abstract
References (45)
Molecular modeling of protein-glycosaminoglycan interactions.
1989 • 1,288 citations
STRUCTURES AND FUNCTIONS OF MULTILIGAND LIPOPROTEIN RECEPTORS: Macrophage Scavenger Receptors and LDL Receptor-Related Protein (LRP)
1994 • 1,175 citations
Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family.
1994 • 550 citations
The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border.
1982 • 539 citations
Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs.
1995 • 338 citations
Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP).
1994 • 323 citations
39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein.
1995 • 305 citations
LDL receptor‐related protein: a multiligand receptor for lipoprotein and proteinase catabolism
1995 • 272 citations
Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo.
1995 • 270 citations
Neonatal Megaloblastic Anemia Due to Inherited Transcobalamin II Deficiency in Two Siblings
1971 • 258 citations
Selective Vitamin B12 Malabsorption and Proteinuria in Young People A Syndrome
1960 • 227 citations
The Heymann nephritis antigenic complex
1995 • 222 citations
Identification of Glycoprotein 330 as an Endocytic Receptor for Apolipoprotein J/Clusterin
1995 • 220 citations
Idiopathic Chronic Megaloblastic Anemia in Children
1960 • 174 citations
Epithelial glycoprotein-330 mediates endocytosis of plasminogen activator-plasminogen activator inhibitor type-1 complexes
1993 • 169 citations
Binding and Uptake of Transcobalamin II by Human Fibroblasts
1978 • 148 citations
Renal tubule gp330 is a calcium binding receptor for endocytic uptake of protein.
1992 • 147 citations
The receptor and epithelial glycoprotein-330: two giant receptors mediating endocytosis of multiple ligands
1994 • 136 citations
Ultrastructural localization by monoclonal antibodies of brush border antigens expressed by glomeruli. II. Extrarenal distribution.
1986 • 131 citations
Characterization of the receptor for transcobalamin II isolated from human placenta.
1978 • 109 citations
Immunological localization of glycoprotein 330, low density lipoprotein receptor related protein and 39 kDa receptor associated protein in embryonic mouse tissues.
1994 • 98 citations
The human alpha 2-macroglobulin receptor contains high affinity calcium binding sites important for receptor conformation and ligand recognition.
1990 • 74 citations
Functional domains of the receptor-associated protein (RAP).
1994 • 65 citations
A new principle in biospecific affinity chromatography used for purification of cobalamin-binding proteins
1975 • 59 citations
The role and fate of rabbit and human transcobalamin II in the plasma transport of vitamin B12 in the rabbit.
1976 • 57 citations
Characterization of the particulate and soluble acceptor for transcobalamin II from human placenta and rabbit liver☆
1980 • 57 citations
Isolation and Characterization of an Abnormal Human Intrinsic Factor
1974 • 52 citations
Membrane Expression and Interactions of Human Transcobalamin II Receptor
1995 • 49 citations
The Regulatory Roles of Liver and Kidney in Cobalamin (Vitamin B12) Metabolism in the Rat: the Uptake and Intracellular Binding of Cobalamin and the Activity of the Cobalamin-Dependent Enzymes in Response to Varying Cobalamin Supply
1984 • 47 citations
Cobalamin malabsorption in three siblings due to an abnormal intrinsic factor that is markedly susceptible to acid and proteolysis.
1985 • 46 citations
Immunofunctional properties of a yolk sac epithelial cell line expressing two proteins gp280 and gp330 of the intermicrovillar area of proximal tubule cells: inhibition of endocytosis by the specific antibodies.
1995 • 41 citations
Uptake of transcobalamin II-bound cobalamin by HL-60 cells: Effects of differentiation induction
1989 • 37 citations
Expression of transcobalamin II mRNA in human tissues and cultured fibroblasts from normal and transcobalamin II-deficient patients
1994 • 35 citations
Sites within the 39-kDa protein important for regulating ligand binding to the low-density lipoprotein receptor-related protein
1995 • 35 citations
Regulation of expression of transcobalamin II receptor in the rat
1995 • 30 citations
GP330 is specifically expressed in outer cells during epithelial differentiation in the preimplantation mouse embryo
1994 • 28 citations
Intrinsic Factor Within Parietal Cells Patients With Juvenile Pernicious Anemia
1985 • 27 citations
Distribution of Endogenous Cobalamin between the Transcobalamins in Various Mammals
1979 • 27 citations
Uptake of transcobalamin II-bound cobalamin by isolated rat kidney tubule cells
1986 • 24 citations
Relative Concentration of Vitamin B12 in the Organs of the Male Rat as Affected by its Intake of the Vitamin
1966 • 14 citations
Cobalamin binding proteins in human seminal plasma
1992 • 13 citations
Application of heparin-conjugated Sepharose for the measurement of cobalamin-saturated and unsaturated transcobalamin II
1988 • 13 citations
Transcobalamin II — Cobalamin binding sites are present on rabbit germ cells
1992 • 10 citations
Studies on the transcobalamin receptor in hog kidney
1991 • 9 citations
Starvation and Renal Uptake of Vitamin B12
1962 • 8 citations