WAY‐100635 antagonist‐induced plasticity of 5‐HT_1A receptors: regulatory differences between a stable cell line and an in vivo native system

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB ₁ Receptor Knockout Mice

1999 • 3,597 citations

The rat brain in stereotaxic coordinates (2nd edn)

1987 • 1,743 citations

5-Hydroxytryptamine receptors

2001 • 693 citations

Distribution and cellular localization of mRNA coding for 5-HT1A receptor in the rat brain: correlation with receptor binding

1992 • 681 citations

Discrimination of Multiple [³H]5‐Hydroxytryptamine Binding Sites by the Neuroleptic Spiperone in Rat Brain

1981 • 629 citations

The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor

1988 • 594 citations

5‐Hydroxytryptamine Receptors

1993 • 524 citations

Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist

1995 • 515 citations

Interaction between a selective 5‐HT_1Areceptor antagonist and an SSRI in vivo: effects on 5‐HT cell firing and extracellular 5‐HT

1995 • 312 citations

The recombinant 5‐HT_1A receptor: G protein coupling and signalling pathways

1999 • 232 citations

Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a []GTPγS binding study

1998 • 225 citations

Clozapine and other 5-hydroxytryptamine-2A receptor antagonists alter the subcellular distribution of 5-hydroxytryptamine-2A receptors in vitro and in vivo

1999 • 166 citations

The 5-HT1A receptor: Signaling, desensitization, and gene transcription

1996 • 127 citations

Quantitative autoradiographic characterisation of the binding of [3H]WAY-100635, a selective 5-HT1A receptor antagonist

1995 • 113 citations

5-Hydroxytryptamine 1A Receptor Blockade Facilitates Aversive Learning in Mice: Interactions with Cholinergic and Glutamatergic Mechanisms

2005 • 98 citations

Identification of residues important for ligand binding to the human 5-hydroxytryptamine1A serotonin receptor.

1993 • 90 citations

Effect of chronic fluoxetine and WAY-100635 treatment on serotonergic neurotransmission in the frontal cortex

2002 • 67 citations

Mechanisms of Ligand-Induced Desensitization of the 5-Hydroxytryptamine_2AReceptor

2002 • 61 citations

The 5-HT1A receptor antagonist WAY 100635 improves rats performance in different models of amnesia evaluated by the object recognition task

2003 • 60 citations

Regional differences in the effect of the combined treatment of WAY 100635 and fluoxetine: an in vivo microdialysis study

1996 • 59 citations

Agonist-Promoted Down-Regulation and Functional Desensitization in Two Naturally Occurring Variants of the Human Serotonin1A Receptor

1997 • 56 citations

Effects of (−)‐tertatolol, (−)‐penbutolol and (±)‐pindolol in combination with paroxetine on presynaptic 5‐HT function: anin vivomicrodialysis and electrophysiological study

1999 • 55 citations

Functional expression of human 5-HT1A receptors and differential coupling to second messengers in CHO cells

1992 • 55 citations

High-level stable expression of recombinant 5-HT1A 5-hydroxytryptamine receptors in Chinese hamster ovary cells

1992 • 54 citations

5-Hydroxytryptamine_1AReceptor-Mediated Increases in Receptor Expression and Activation of Nuclear Factor-κB in Transfected Chinese Hamster Ovary Cells

1997 • 46 citations

Agonist-induced desensitization and loss of high-affinity binding sites of stably expressed human 5-HT1A receptors.

1994 • 45 citations

The putative «silent» 5-HT1A receptor antagonist, WAY 100635, has inverse agonist properties at cloned human 5-HT1A receptors

2000 • 38 citations

Anxiolytic-like effects of the selective 5-HT1A receptor antagonist WAY 100635 in non-human primates

2003 • 37 citations

Effects of selective 5-HT1A receptor antagonists on regional serotonin synthesis in the rat brain: An autoradiographic study with α-[14C]methyl-l-tryptophan

2001 • 36 citations

Pharmacological characterization of recombinant human 5-hydroxytryptamine1A receptors using a novel antagonist radioligand, [3H]way-100635

1997 • 30 citations

Expression and modulation of 5-hydroxytryptamine1A receptors in P11 cells.

1996 • 21 citations

Further characterisation of [3H]8-hydroxy-2-(di-N-propylamino)tetralin binding sites in human brain postmortem

1997 • 10 citations

Lack of stereoselectivity of 8-hydroxy-2(di-N-propylamino)tetralin-mediated inhibition of forskolin-stimulated adenylyl cyclase activity in human pre- and post-synaptic brain regions

2000 • 5 citations