Agonist-Promoted Down-Regulation and Functional Desensitization in Two Naturally Occurring Variants of the Human Serotonin1A Receptor

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

MODEL SYSTEMS FOR THE STUDY OF SEVEN-TRANSMEMBRANE-SEGMENT RECEPTORS

1991 • 1,357 citations

Current advances and trends in the treatment of depression

1994 • 1,111 citations

Amino-Terminal Polymorphisms of the Human .beta.2-Adrenergic Receptor Impart Distinct Agonist-Promoted Regulatory Properties

1994 • 780 citations

5-Hydroxytryptamine receptors

2001 • 693 citations

Molecular biology of 5-HT receptors

1994 • 679 citations

Mutations in the Gene Encoding for the β₂-adrenergic Receptor in Normal and Asthmatic Subjects

1993 • 633 citations

5‐Hydroxytryptamine Receptors

1993 • 524 citations

An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins

1987 • 509 citations

5-HT1A receptor agonists: recent developments and controversial issues

1995 • 463 citations

Influence of beta 2-adrenergic receptor genotypes on signal transduction in human airway smooth muscle cells.

1995 • 443 citations

Characterization of the 5-hydroxytryptamine1a receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes.

1986 • 420 citations

Serotonin receptors in the human brain. I. Characterization and autoradiographic localization of 5-HT1A recognition sites. Apparent absence of 5-HT1B recognition sites

1986 • 386 citations

Structural features required for ligand binding to the beta-adrenergic receptor.

1987 • 358 citations

Effectiveness of Pindolol With Selected Antidepressant Drugs in the Treatment of Major Depression

1995 • 323 citations

Association of Glu 27 β2-adrenoceptor polymorphism with lower airway reactivity in asthmatic subjects

1995 • 298 citations

The distribution of 5-HT1A and 5-HT2A receptor mRNA in human brain

1995 • 272 citations

Pharmacology of 5-hydroxytryptamine-1A receptors which inhibit cAMP production in hippocampal and cortical neurons in primary culture.

1988 • 150 citations

From ligand binding to gene expression: new insights into the regulation of G-protein-coupled receptors

1992 • 143 citations

The 5-HT1A receptor: Signaling, desensitization, and gene transcription

1996 • 127 citations

Protein kinase C induces phosphorylation and desensitization of the human 5-HT1A receptor

1991 • 115 citations

Molecular biology of serotonin (5‐HT) receptors

1994 • 98 citations

Identification of residues important for ligand binding to the human 5-hydroxytryptamine1A serotonin receptor.

1993 • 90 citations

Systematic screening for mutations in the promoter and the coding region of the 5‐HT_1A gene

1995 • 66 citations

Functional expression of human 5-HT1A receptors and differential coupling to second messengers in CHO cells

1992 • 55 citations

High-level stable expression of recombinant 5-HT1A 5-hydroxytryptamine receptors in Chinese hamster ovary cells

1992 • 54 citations

2 Naturally Occurring Amino Acid Substitutions in the Human 5-HT1A Receptor: Glycine 22 to Serine 22 and Isoleucine 28 to Valine 28

1995 • 51 citations

5-HT-1A receptor-mediated effects of antidepressants

1993 • 39 citations

Localization and gene expression of serotonin1A (5HT1A) receptors in human brain postmortem

1994 • 36 citations

Binding properties of the naturally occurring human 5-HT1A receptor variant with the Ile28Val substitution in the extracellular domain

1995 • 21 citations

Improved Models for Pharmacological Null Experiments: Calculation of Drug Efficacy at Recombinant D1A Dopamine Receptors Stably Expressed in Clonal Cell Lines

1996 • 14 citations

Mass allele detection (MAD) of rare 5-HT1A structural variants with allele-specific amplification and electrochemiluminescent detection

1996 • 13 citations

Mass allele detection (MAD) of rare 5‐HT1A structural variants with allele‐specific amplification and electrochemiluminescent detection

1996 • 4 citations