Galectin‐1 supports survival of naive T cells without promoting cell proliferation

Galectins and their ligands: amplifiers, silencers or tuners of the inflammatory response?

2002 • 535 citations

Recombinant Galectin-1 and Its Genetic Delivery Suppress Collagen-Induced Arthritis via T Cell Apoptosis

1999 • 358 citations

Regulation of apoptosis in vitro in mature murine spleen T cells.

1993 • 313 citations

Galectin-1, an Endogenous Lectin Produced by Thymic Epithelial Cells, Induces Apoptosis of Human Thymocytes

1997 • 298 citations

Human thymic epithelial cells express an endogenous lectin, galectin-1, which binds to core 2 O-glycans on thymocytes and T lymphoblastoid cells.

1995 • 260 citations

Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering

2002 • 260 citations

Hierarchical Control of Lymphocyte Survival

1996 • 255 citations

Homeostasis of αβ TCR+ T cells

2000 • 251 citations

β-Galactoside-binding protein secreted by activated T cells inhibits antigen-induced proliferation of T cells

1998 • 237 citations

Ah, sweet mystery of death! Galectins and control of cell fate

2002 • 211 citations

Galectin-1 Induces Partial TCR ζ-Chain Phosphorylation and Antagonizes Processive TCR Signal Transduction

2000 • 207 citations

Galectin-1 Specifically Modulates TCR Signals to Enhance TCR Apoptosis but Inhibit IL-2 Production and Proliferation

1999 • 188 citations

Galectin-1 Accumulation in the Ovary Carcinoma Peritumoral Stroma Is Induced by Ovary Carcinoma Cells and Affects Both Cancer Cell Proliferation and Adhesion to Laminin-1 and Fibronectin

2003 • 174 citations

Molecular mechanisms implicated in galectin-1-induced apoptosis: activation of the AP-1 transcription factor and downregulation of Bcl-2

2000 • 143 citations

NAC covers ribosome-associated nascent chains thereby forming a protective environment for regions of nascent chains just emerging from the peptidyl transferase center.

1995 • 131 citations

T lymphocytes need IL-7 but not IL-4 or IL-6 to survive in vivo

2001 • 128 citations

Induction of allogenic T-cell hyporesponsiveness by galectin-1-mediated apoptotic and non-apoptotic mechanisms

2002 • 116 citations

Galectin-1 Modulates Human Melanoma Cell Adhesion to Laminin

1995 • 116 citations

Alterations in Cell Surface Carbohydrates on T Cells from Virally Infected Mice Can Distinguish Effector/Memory CD8+ T Cells from Naive Cells

1998 • 105 citations

Normal Regulatory α/β T Cells Effectively Eliminate Abnormally Activated T Cells Lacking the Interleukin 2 Receptor β in Vivo

1999 • 99 citations

The α and β Subunit of the Nascent Polypeptide-associated Complex Have Distinct Functions

2000 • 99 citations

Spontaneous Release of Cytosolic Proteins from Posttranslational Substrates before Their Transport into the Endoplasmic Reticulum

2000 • 93 citations

The effect of galectin-1 on the differentiation of fibroblasts and myoblasts in vitro

2002 • 91 citations

T-cell survival

1998 • 90 citations

Differential splicing-in of a proline-rich exon converts alphaNAC into a muscle-specific transcription factor.

1996 • 87 citations

Bone-Specific Expression of the Alpha Chain of the Nascent Polypeptide-Associated Complex, a Coactivator Potentiating c-Jun-Mediated Transcription

1998 • 86 citations

Beta-galactoside-binding protein (beta GBP) alters the cell cycle, up-regulates expression of the alpha- and beta-chains of the IFN-gamma receptor, and triggers IFN-gamma-mediated apoptosis of activated human T lymphocytes.

1998 • 81 citations

Specific Inhibition of Lymphocyte Proliferation and Induction of Apoptosis by CLL-I, a -Galactoside-Binding Lectin

1997 • 61 citations

β-Galactoside-Binding Protein (βGBP) Alters the Cell Cycle, Up-Regulates Expression of the α- and β-Chains of the IFN-γ Receptor, and Triggers IFN-γ-Mediated Apoptosis of Activated Human T Lymphocytes

1998 • 60 citations

Identification of cells expressing galectin‐1, a galactose‐binding receptor, in the rat olfactory system

1995 • 54 citations

A Proteome Study of Secreted Prostatic Factors Affecting Osteoblastic Activity: Galectin-1 Is Involved in Differentiation of Human Bone Marrow Stromal Cells

2003 • 49 citations

Characterization of a Novel Isoform of α-Nascent Polypeptide-associated Complex as IgE-defined Autoantigen

2002 • 40 citations

Purification and Characterization of a Human Brain Galectin‐1 Ligand

1997 • 22 citations

The African Swine Fever Virus Protein j4R Binds to the Alpha Chain of Nascent Polypeptide-Associated Complex

2002 • 21 citations

Murine lymph node‐derived stromal cells effectively support survival but induce no activation/proliferation of peripheral resting T cells in vitro

2003 • 14 citations

Antigenic determinants encoded by alternatively spliced exons of CD45 are determined by the polypeptide but influenced by glycosylation

1994 • 13 citations