T-cell survival

Tolerance, Danger, and the Extended Family

1994 • 4,654 citations

Approaching the Asymptote? Evolution and Revolution in Immunology

1989 • 3,079 citations

A family of cytokine-inducible inhibitors of signalling

1997 • 2,055 citations

Structure and function of a new STAT-induced STAT inhibitor

1997 • 1,308 citations

Potent and Selective Stimulation of Memory-Phenotype CD8+ T Cells In Vivo by IL-15

1998 • 1,262 citations

Induction of apoptosis in mature T cells by tumour necrosis factor

1995 • 1,139 citations

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

1994 • 967 citations

Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity

1990 • 904 citations

Turnover of naive- and memory-phenotype T cells.

1994 • 900 citations

Differential Requirements for Survival and Proliferation of CD8 Naïve or Memory T Cells

1997 • 875 citations

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

1994 • 708 citations

Programmed cell death and extrathymic reduction of Vβ8+CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B

1991 • 675 citations

Peripheral T Cell Survival Requires Continual Ligation of the T Cell Receptor to Major Histocompatibility Complex–Encoded Molecules

1997 • 419 citations

Cytokine-induced survival of activated T cellsin vitroandin vivo

1998 • 395 citations

MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

1996 • 377 citations

Interleukin‐2 receptor common γ‐chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: Selective induction of anti‐apoptotic (bcl‐2, bcl‐x_L) but not pro‐apoptotic (bax, bcl‐x_S) gene expression

1996 • 367 citations

Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo

1989 • 351 citations

Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4.

1995 • 323 citations

Interleukin 4 (IL-4) or IL-7 Prevents the Death of Resting T Cells: Stat6 Is Probably Not Required for the Effect of IL-4

1997 • 293 citations

IL-6 rescues resting mouse T cells from apoptosis.

1997 • 246 citations

Profound deletion of mature T cells in vivo by chronic exposure to exogenous superantigen.

1993 • 241 citations

Lipopolysaccharide interferes with the induction of peripheral T cell death

1995 • 240 citations

The life span of naive alpha/beta T cells in secondary lymphoid organs.

1993 • 130 citations

Fas ligand-mediated cytotoxicity is directly responsible for apoptosis of normal CD4+ T cells responding to a bacterial superantigen.

1995 • 119 citations

SOCS-1/JAB/SSI-1 Can Bind to and Suppress Tec Protein-tyrosine Kinase

1997 • 117 citations

Functional heterogeneity among the T-derived lymphocytes of the mouse. I. Analysis by adult thymectomy.

1974 • 105 citations

Functional Heterogeneity among the T-Derived Lymphocytes of the Mouse

1974 • 68 citations