T cell recognition of ragweed allergen Ra3: Localization of the full T cell recognition profile by synthetic overlapping peptides representing the entire protein chain

Membrane properties of living mammalian cells as studied by enzymatic hydrolysis of fluorogenic esters.

1966 • 1,150 citations

The Antigenic Structure of Proteins: A Reappraisal

1984 • 957 citations

Antigenic structure of myoglobin: The complete immunochemical anatomy of a protein and conclusions relating to antigenic structures of proteins

1975 • 474 citations

Precise determination of the entire antigenic structure of lysozyme: Molecular features of protein antigenic structures and potential of ‘surface-simulation’ synthesis—a powerful new concept for protein binding sites

1978 • 246 citations

Antigenic structures of proteins. Their determination has revealed important aspects of immune recognition and generated strategies for synthetic mimicking of protein binding sites

1984 • 245 citations

Genetic control of immune response to sperm whale myoglobin in mice. II. T lymphocyte proliferative response to the synthetic antigenic sites.

1979 • 121 citations

A novel and comprehensive synthetic approach for the elucidation of protein antigenic structures. Determination of the full antigenic profile of the α-chain of human haemoglobin

1980 • 114 citations

Immunochemistry of sperm-whale myoglobin

1973 • 109 citations

Immunochemistry of sperm-whale myoglobin—XVI: Accurate delineation of the single region in sequence 1–55 by immunochemical studies of synthetic peptides. Some conclusions concerining antigenic structures of proteins

1974 • 104 citations

Genetic Control of Immune Response to Sperm Whale Myoglobin in Mice

1979 • 99 citations

Precise determination of protein antigenic structures has unravelled the molecular immune recognition of proteins and provided a prototype for synthetic mimicking of other protein binding sites

1980 • 96 citations

Genetic control of immune response to sperm whale myoglobin in mice. I. T lymphocyte proliferative response under H-2-linked Ir gene control.

1978 • 86 citations

Structurally inherent antigenic sites. Localization of the antigenic sites of the α-chain of human haemoglobin in three host species by a comprehensive synthetic approach

1982 • 81 citations

Reconstitution of horse heart cytochrome c: Reformation of the peptide bond linking residues 65 and 66

1974 • 68 citations

Genetic Control of Immune Response to Sperm Whale Myoglobin in Mice

1978 • 61 citations

Molecular Localization of the Full Profile of the Continuous Regions Recognized by Myoglobin Primed T-Cells Using Synthetic Overlapping Peptides Encompassing the Entire Molecule

1983 • 56 citations

T CELL RECOGNITION OF MYOGLOBIN : LOCALIZATION OF THE SITES STIMULATING T CELL PROLIFERATIVE RESPONSES BY SYNTHETIC OVERLAPPING PEPTIDES ENCOMPASSING THE ENTIRE MOLECULE

1984 • 52 citations

Production of Monoclonal Antibodies to Surface Regions that are Non-Immunogenic in a Protein Using Free Synthetic Peptide as Immunogens: Demonstration with Sperm-Whale Myoglobin

1983 • 45 citations

Preparation of T-lymphocyte lines and clones with specificities to preselected protein sites by in vitro passage with free synthetic peptides: Demonstration with myoglobin sites

1983 • 44 citations

Antibody recognition of ragweed allergen Ra3: Localization of the full profile of the continuous antigenic sites by synthetic overlapping peptides representing the entire protein chain

1986 • 43 citations

Genetic Control and Intersite Influences on the Immune Response to Sperm Whale Myoglobin

1982 • 36 citations

T CELL RECOGNITION OF LYSOZYME IV. LOCALIZATION AND GENETIC CONTROL OF THE CONTINUOUS T CELL RECOGNITION SITES BY SYNTHETIC OVERLAPPING PEPTIDES REPRESENTING THE ENTIRE PROTEIN CHAIN

1984 • 30 citations

GENETIC CONTROL OF THE IMMUNE RESPONSE TO HAEMOGLOBIN: I. DEMONSTRATION OF SEPARATE GENETIC CONTROL OF THE RESPONSES TO THE α‐ AND β‐SUBUNITS BY IN VITRO LYMPHOCYTE PROLIFERATION

1981 • 24 citations

III. RECOGNITION OF THE ‘SURFACE‐SIMULATION’ SYNTHETIC ANTIGENIC STIES

1984 • 20 citations

T‐LYMPHOCYTE RECOGNITION OF SPERM‐WHALE MYOGLOBIN. SPECIFICITY OF T‐CELL RECOGNITION FOLLOWING NEONATAL TOLERANCE WITH EITHER MYOGLOBIN OR SYNTHETIC PEPTIDES OF AN ANTIGENIC SITE

1983 • 17 citations

Localization of the continuous allergenic sites of ragweed allergen Ra3 by a comprehensive synthetic strategy

1985 • 15 citations

T Cell Recognition of Lysozyme. II. Shift in Specificity During Long-Term Culture Determined by Synthetic Overlapping Peptides Comprising the Entire Protein Chain

1984 • 9 citations

Genetic Control of the Immune Response to Myoglobin. V. Analysis of the Cross-Reactivity of 12 Myoglobins with Sperm-Whale Myoglobin Antisera of Inbred Mouse Strains in Terms of Substitutions in the Antigenic Sites and in the Environmental Residues of the Sites

1981 • 8 citations