T CELL RECOGNITION OF LYSOZYME IV. LOCALIZATION AND GENETIC CONTROL OF THE CONTINUOUS T CELL RECOGNITION SITES BY SYNTHETIC OVERLAPPING PEPTIDES REPRESENTING THE ENTIRE PROTEIN CHAIN

Membrane properties of living mammalian cells as studied by enzymatic hydrolysis of fluorogenic esters.

1966 • 1,150 citations

The Amino Acid Sequence of Egg White Lysozyme

1963 • 726 citations

Antigenic structure of myoglobin: The complete immunochemical anatomy of a protein and conclusions relating to antigenic structures of proteins

1975 • 474 citations

Lymphocyte specificity to protein antigens. I. Characterization of the antigen-induced in vitro T cell-dependent proliferative response with lymph node cells from primed mice.

1977 • 361 citations

The Disulfide Bonds of Egg White Lysozyme (Muramidase)

1965 • 258 citations

La structure chimique du lysozyme de blanc d'oeuf de poule: étude détaillée

1963 • 253 citations

Precise determination of the entire antigenic structure of lysozyme: Molecular features of protein antigenic structures and potential of ‘surface-simulation’ synthesis—a powerful new concept for protein binding sites

1978 • 246 citations

Processing of lysozyme by macrophages: identification of the determinant recognized by two T-cell hybridomas.

1984 • 175 citations

A proposal for the nomenclature of antigenic sites in peptides and proteins

1978 • 166 citations

T lymphocyte-enriched murine peritoneal exudate cells. I. A reliable assay for antigen-induced T lymphocyte proliferation.

1975 • 135 citations

Genetic control of immune response to sperm whale myoglobin in mice. II. T lymphocyte proliferative response to the synthetic antigenic sites.

1979 • 121 citations

A novel and comprehensive synthetic approach for the elucidation of protein antigenic structures. Determination of the full antigenic profile of the α-chain of human haemoglobin

1980 • 114 citations

The precise and entire antigenic structure of native lysozyme

1978 • 114 citations

Immunochemistry of sperm-whale myoglobin

1973 • 109 citations

Immunochemistry of sperm-whale myoglobin—XVI: Accurate delineation of the single region in sequence 1–55 by immunochemical studies of synthetic peptides. Some conclusions concerining antigenic structures of proteins

1974 • 104 citations

Epitope specificity of the T cell proliferative response to lysozyme: proliferative T cells react predominantly to different determinants from those recognized by B cells

1980 • 101 citations

Genetic Control of Immune Response to Sperm Whale Myoglobin in Mice

1979 • 99 citations

Lack of immunochemical cross-reaction between lysozyme and α-lactalbumin and comparison of their conformations

1970 • 83 citations

T Lymphocyte-Enriched Murine Peritoneal Exudate Cells

1975 • 82 citations

Structurally inherent antigenic sites. Localization of the antigenic sites of the α-chain of human haemoglobin in three host species by a comprehensive synthetic approach

1982 • 81 citations

Enzymic and immunochemical properties of lysozyme

1971 • 72 citations

Localization, synthesis, and activity of an antigenic site on influenza virus hemagglutinin.

1983 • 69 citations

Enzymic and immunochemical properties of lysozyme. Accurate definition of the antigenic site around the disulphide bridge 30-115 (site 3) by ‘surface simulation’ synthesis

1977 • 69 citations

Immunochemical studies on lysozyme and carboxymethylated lysozyme

1970 • 69 citations

Enzymic and immunochemical properties of lysozyme XVI. A novel synthetic approach to an antigenic reactive site by direct linkage of the relevant conformationally adjacent residues constituting the site

1976 • 68 citations

Delineation of the third antigenic site of lysozyme by application of a novel ‘surface-simulation’ synthetic approach directly linking the conformationally adjacent residues forming the site

1976 • 63 citations

Genetic control of the immune response to myoglobin. IV. Mouse antibodies in outbred and congenic strains against sperm-whale myoglobin recognize the same antigenic sites that are recognized by antibodies raised in other species

1981 • 63 citations

Antigenic properties of egg-white lysozyme. I. Isolation and characterization of a tryptic peptide from reduced and alkylated lysozyme exhibiting haptenic activity

1968 • 59 citations

Molecular Localization of the Full Profile of the Continuous Regions Recognized by Myoglobin Primed T-Cells Using Synthetic Overlapping Peptides Encompassing the Entire Molecule

1983 • 56 citations

Immunochemistry of serum albumin. X. five major antigenic sites of human serum albumin are extrapolated from bovine albumin and confirmed by synthetic peptides

1980 • 55 citations

Localization and verification by synthesis of five antigenic sites of bovine serum albumin

1979 • 52 citations

Can the Lumpy Distribution of Galaxies be Detected by X-ray observations ?

1972 • 51 citations

Lysozymes characterized in Duck Egg-white: Isolation of a Histidine-less Lysozyme

1965 • 49 citations

Conformational studies on modified proteins and peptides. VI. Conformation and immunochemistry of methylated and carboxymethylated derivatives of lysozyme

1973 • 41 citations

Enzymic and immunochemical properties of lysozyme

1977 • 39 citations

GENETIC CONTROL OF THE IMMUNE RESPONSE TO HEN'S EGG‐WHITE LYSOZYME IN MICE: I. ANTIBODY AND T‐LYMPHOCYTE PROLIFERATIVE RESPONSES TO THE NATIVE PROTEIN*

1979 • 39 citations

Boundary refinement of the lysozyme antigenic site around the disulphide bond 6–127 (site 1) by ‘surface-simulation’ synthesis

1978 • 39 citations

A NOVEL APPROACH FOR LOCALIZATION OF THE CONTINUOUS PROTEIN ANTIGENIC SITES BY COMPREHENSIVE SYNTHETIC SURFACE SCANNING: ANTIBODY AND T-CELL ACTIVITY TO SEVERAL INFLUENZA HEMAGGLUTININ SYNTHETIC SITES

1984 • 32 citations

Antibodies to a continuous region at residues 38-54 of hen egg white lysozyme found in a small fraction of anti-hen egg white lysozyme antibodies

1980 • 31 citations

Immunochemistry of the Tobacco Mosaic Virus Protein

1977 • 30 citations

Chemical Modification and Cleavage of Proteins and Chemical Strategy in Immunochemical Studies of Proteins

1977 • 29 citations

Genetic control of the immune response to myoglobin. VI. Inter-site influences in T-lymphocyte proliferative response from analysis of cross-reactions of ten myoglobins in terms of substitutions in the antigenic sites and in environmental residues of the sites

1981 • 28 citations

Immune recognition of cytochrome c. I. Investigation by synthesis whether antigenic sites of polymeric cytochrome coincide with locations of sequence differences between the immunizing and host cytochromes

1981 • 25 citations

GENETIC CONTROL OF THE IMMUNE RESPONSE TO HAEMOGLOBIN: I. DEMONSTRATION OF SEPARATE GENETIC CONTROL OF THE RESPONSES TO THE α‐ AND β‐SUBUNITS BY IN VITRO LYMPHOCYTE PROLIFERATION

1981 • 24 citations

Immune recognition of serum albumin. 15

1982 • 23 citations

Dissection of the Molecular Parameters for T-Cell Recognition of a Myoglobin Antigenic Site

1982 • 22 citations

III. RECOGNITION OF THE ‘SURFACE‐SIMULATION’ SYNTHETIC ANTIGENIC STIES

1984 • 20 citations

T‐LYMPHOCYTE RECOGNITION OF SPERM‐WHALE MYOGLOBIN. RESPONSES OF T‐CELLS FROM MOUSE STRAINS PRIMED WITH SYNTHETIC PEPTIDE CARRYING ANTIGENIC SITE 5 AND RELATION TO ANTIGEN PRESENTATION

1983 • 16 citations

CELL-MEDIATED AND HUMORAL IMMUNITY IN MICE: CROSS REACTION BETWEEN LYSOZYME AND S-CARBOXYMETHYLATED LYSOZYME STUDIED BY A MODIFIED FOOTPAD TEST

1975 • 15 citations

Regulation of Delayed-Type Hypersensitivity (DTH) response to Hen Egg-white Lysozyme (HEL)

1981 • 15 citations

T-cell recognition of lysozyme. I. Localization of regions stimulating T-cell proliferative response by synthetic overlapping peptides encompassing the entire molecule.

1984 • 15 citations

Immunochemical Studies on the Tobacco Mosaic Virus Protein

1978 • 13 citations

T Cell Recognition of Lysozyme. II. Shift in Specificity During Long-Term Culture Determined by Synthetic Overlapping Peptides Comprising the Entire Protein Chain

1984 • 9 citations

Recognition of Lysozyme by Lymphocyte Subsets

1978 • 9 citations