Redefining the lipophilin family of proteolipid proteins

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

PROTEOLIPIDES, A NEW TYPE OF TISSUE LIPOPROTEINS

1951 • 773 citations

Predicting the orientation of eukaryotic membrane-spanning proteins.

1989 • 596 citations

Assembly of CNS Myelin in the Absence of Proteolipid Protein

1997 • 454 citations

Crystal Structure of the Extracellular Domain from P0, the Major Structural Protein of Peripheral Nerve Myelin

1996 • 412 citations

Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin.

1987 • 300 citations

Oligodendrocytes originate in a restricted zone of the embryonic ventral neural tube defined by DM-20 mRNA expression

1995 • 296 citations

Premature arrest of myelin formation in transgenic mice with increased proteolipid protein gene dosage

1994 • 277 citations

Glial cell degeneration and hypomyelination caused by overexpression of myelin proteolipid protein gene

1994 • 263 citations

Proteolipid protein (PLP) of CNS myelin: positions of free, disulfide-bonded, and fatty acid thioester-linked cysteine residues and implications for the membrane topology of PLP

1992 • 227 citations

A cellular mechanism governing the severity of Pelizaeus–Merzbacher disease

1996 • 224 citations

Disruption of the compacted myelin sheath of axons of the central nervous system in proteolipid protein-deficient mice.

1994 • 222 citations

Many naturally occurring mutations of myelin proteolipid protein impair its intracellular transport

1994 • 159 citations

Isolation of a highly purified myelin protein

1971 • 150 citations

A proteolipid protein gene family: Expression in sharks and rays and possible evolution from an ancestral gene encoding a pore-forming polypeptide

1993 • 150 citations

Molecular cloning of M6: Identification of a PLP/DM20 gene family

1993 • 143 citations

Molecular Organization of Myelin

1984 • 141 citations

Genetics of Pelizaeus-Merzbacher Disease

1993 • 137 citations

A myelin proteolipid protein-LacZ fusion protein is developmentally regulated and targeted to the myelin membrane in transgenic mice.

1993 • 123 citations

Monoclonal M6 antibody interferes with neurite extension of cultured neurons

1992 • 112 citations

Parallel Evolution and Coexpression of the Proteolipid Proteins and Protein Zero in Vertebrate Myelin

1996 • 105 citations

The major myelin protein genes are expressed in the human thymus

1996 • 100 citations

X-Linked Developmental Defects of Myelination: From Mouse Mutants to Human Genetic Diseases

1996 • 83 citations

Phylogeny of Myelin Proteins

1990 • 82 citations

DM20 mRNA splice product of the myelin proteolipid protein gene is expressed in the murine heart

1992 • 82 citations

Conservation of Topology, But Not Conformation, of the Proteolipid Proteins of the Myelin Sheath

1997 • 68 citations

Refined genetic mapping and proteolipid protein mutation analysis in X-linked pure hereditary spastic paraplegia

1996 • 65 citations

Expression of members of the proteolipid protein gene family in the developing murine central nervous system

1996 • 64 citations

Myelin structure in proteolipid protein (PLP)-null mouse spinal cord

1996 • 64 citations

Decompaction of CNS myelin leads to a reduction of the conduction velocity of action potentials in optic nerve

1995 • 61 citations

EMA: A developmentally regulated cell‐surface glycoprotein of CNS neurons that is concentrated at the leading edge of growth cones

1992 • 49 citations

Dissection of the Phenotype and Genotype of the X‐Linked Myelin Mutants^a

1990 • 40 citations

Calcium Movements Mediated by Proteolipid Protein and Nucleotides in Liposomes Prepared with the Endogenous Lipids from Brain White Matter

1990 • 38 citations

Myelin Proteolipid Protein (PLP), but Not DM-20, Is an Inositol Hexakisphosphate-binding Protein

1996 • 36 citations

Myelination and dysmyelination

1989 • 30 citations

Chromosomal Mapping of the Human M6 Genes

1996 • 28 citations

Differential Localization and pH Dependency of Phosphoinositide 1,4,5‐IP₃, 1,3,4,5‐IP₄ and IP₆ Receptors in Rat and Human Brains

1994 • 21 citations

Orientation of myelin proteolipid protein in the oligodendrocyte cell membrane

1996 • 17 citations

Identification of thiol groups and a disulfide crosslink site in bovine myelin proteolipid protein

1989 • 13 citations

The Proteolipid Protein Gene Family: Three New Members and Evidence for Their Common Origin from a Primitive Membrane Channel

1994 • 1 citations