Parallel Evolution and Coexpression of the Proteolipid Proteins and Protein Zero in Vertebrate Myelin

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs

1992 • 1,067 citations

Isolation and sequence of a cDNA encoding the major structural protein of peripheral myelin

1985 • 538 citations

Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons

1992 • 493 citations

Synthesis and incorporation of myelin polypeptides into CNS myelin.

1982 • 422 citations

Nucleotide sequences of two mRNAs for rat brain myelin proteolipid protein

1985 • 345 citations

Role of myelin Po protein as a homophilic adhesion molecule

1990 • 344 citations

Two forms of 1B236/myelin-associated glycoprotein, a cell adhesion molecule for postnatal neural development, are produced by alternative splicing.

1987 • 320 citations

Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin.

1987 • 300 citations

Protein zero of peripheral nerve myelin: Biosynthesis, membrane insertion, and evidence for homotypic interaction

1990 • 276 citations

The origin and early diversification of tetrapods

1994 • 228 citations

Proteolipid protein (PLP) of CNS myelin: positions of free, disulfide-bonded, and fatty acid thioester-linked cysteine residues and implications for the membrane topology of PLP

1992 • 227 citations

Compact myelin exists in the absence of basic protein in the shiverer mutant mouse

1980 • 224 citations

Disruption of the compacted myelin sheath of axons of the central nervous system in proteolipid protein-deficient mice.

1994 • 222 citations

Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing.

1986 • 219 citations

Uncoupling of hypomyelination and glial cell death by a mutation in the proteolipid protein gene

1992 • 212 citations

DM‐20 mRNA Is Expressed During the Embryonic Development of the Nervous System of the Mouse

1992 • 173 citations

Animal Models of Genetic Disorders of Myelin

1984 • 159 citations

The structural gene coding for myelin-associated proteolipid protein is mutated in jimpy mice

1986 • 154 citations

Myelin‐specific proteolipid protein is expressed in myelinating schwann cells but is not incorporated into myelin sheaths

1987 • 154 citations

Adhesive properties of proteolipid protein are responsible for the compaction of CNS myelin sheaths

1995 • 152 citations

A proteolipid protein gene family: Expression in sharks and rays and possible evolution from an ancestral gene encoding a pore-forming polypeptide

1993 • 150 citations

Molecular cloning of M6: Identification of a PLP/DM20 gene family

1993 • 143 citations

Selective Expression of DM‐20, an Alternatively Spliced Myelin Proteolipid Protein Gene Product, in Developing Nervous System and in Nonglial Cells

1992 • 141 citations

Molecular Organization of Myelin

1984 • 141 citations

Recombinant peripheral myelin protein P_o confers both adhesion and neurite outgrowth‐promoting properties

1990 • 133 citations

Structure and expression of the mouse myelin proteolipid protein gene

1987 • 130 citations

Paedomorphosis and Simplification in the Nervous System of Salamanders; pp. 137–152

1993 • 125 citations

Monoclonal M6 antibody interferes with neurite extension of cultured neurons

1992 • 112 citations

[14]Xenopus oocyte microinjection: From gene to protein

1992 • 102 citations

Neurological mouse mutants and the genes of myelin

1994 • 97 citations

An AG→GG transition at a splice site in the myelin proteolipid protein gene in jimpy mice results in the removal of an exon

1987 • 95 citations

Brain Proteolipids

1983 • 88 citations

The myelin proteins of the shark brain are similar to the myelin proteins of the mammalian peripheral nervous system

1989 • 85 citations

Prehistoric Extinction of Giant Iguanas in Tonga

1989 • 85 citations

Phylogeny of Myelin Proteins

1990 • 82 citations

Peripheral myelin in the mouse mutant Shiverer

1980 • 82 citations

Myelin Membrane Structure and Composition Correlated: A Phylogenetic Study

1989 • 82 citations

Characterization of Myelin Proteolipid mRNAs in Normal and Jimpy Mice

1986 • 80 citations

Appearance of Myelin proteins during vertebrate evolution

1986 • 78 citations

Central nervous system myelin proteins and glycoproteins in vertebrates: A phylogenetic study

1981 • 73 citations

Phylogenetic Relationships of the Angel Sharks, with Comments on Elasmobranch Phylogeny (Chondrichthyes, Squatinidae)

1992 • 70 citations

Characterization of myelin proteolipid mRNAs in normal and jimpy mice.

1986 • 69 citations

Phylogenetic examination of vertebrate central nervous system myelin proteins by electro-immunoblotting

1985 • 66 citations

Expression of myelin proteins in the developing human spinal cord: Cloning and sequencing of human proteolipid protein cDNA

1987 • 64 citations

Proteolipid protein interactions in transfectants: Implications for myelin assembly

1994 • 62 citations

Evolution of the Myelin Integral Membrane Proteins of the Central Nervous System

1991 • 61 citations

Molecular evidence on the origin of tetrapods and the relationships of the coelacanth

1995 • 61 citations

Molecular cloning and nucleotide sequence of a cDNA clone coding for rat brain myelin proteolipid

1985 • 58 citations

Interactions of Folch-Lees proteolipid apoprotein with planar lipid bilayers

1979 • 57 citations

Protein zero, a nervous system adhesion molecule, triggers epithelial reversion in host carcinoma cells.

1995 • 55 citations

Interactions of dicyclohexylcarbodiimide with myelin proteolipid.

1982 • 50 citations

EMA: A developmentally regulated cell‐surface glycoprotein of CNS neurons that is concentrated at the leading edge of growth cones

1992 • 49 citations

Human myelin DM-20 proteolipid protein deletion defined by cDNA sequence

1987 • 42 citations

Dissection of the Phenotype and Genotype of the X‐Linked Myelin Mutants^a

1990 • 40 citations

Calcium Movements Mediated by Proteolipid Protein and Nucleotides in Liposomes Prepared with the Endogenous Lipids from Brain White Matter

1990 • 38 citations

Major Central Nervous System Myelin Glycoprotein of the African Lungfish (Protopterus dolloi) Cross-Reacts with Myelin Proteolipid Protein Antibodies, Indicating a Close Phylogenetic Relationship with Amphibians

1986 • 38 citations

The DM20 Protein of Myelin: Intracellular and Surface Expression Patterns in Transfectants

1992 • 31 citations

Hypomyelination in the peripheral nervous system of shiverer mice and in Shiverer ↔ Normal chimaera

1984 • 31 citations

Molecular Cloning and Tissue Expression of a cDNA Encoding IP1—A P₀‐Like Glycoprotein of Trout CNS Myelin

1995 • 29 citations

Cloned Proteolipid Protein and Myelin Basic Protein cDNA. Transcription of the Two Genes During Myelination

1986 • 28 citations

Presence of Proteolipid Protein in Coelacanth Brain Myelin Demonstrates Tetrapod Affinities and Questions a Chondrichthyan Association

1989 • 23 citations

Ionophoric properties of the proteolipid apoprotein from bovine brain myelin.

1987 • 17 citations

Expression of myelin proteins characteristic of fish and tetrapods by Polypterus revitalizes long discredited phylogenetic links

1986 • 16 citations

A glycosylated proteolipid protein is common to CNS myelin of recent lungfish (Ceratodiae, Lepidosirenidae)

1987 • 15 citations

Isolation and characterization of a cDNA encoding the zebra finch myelin proteolipid protein

1994 • 15 citations

Expression of a P0-like glycoprotein in central nervous system myelin of amphibians (Ambystoma mexicanus, xenopus laevis and Rana catesbeiana)

1993 • 11 citations