VEGFR-3 and Its Ligand VEGF-C Are Associated with Angiogenesis in Breast Cancer

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1991 • 8,402 citations

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1995 • 7,717 citations

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1997 • 4,359 citations

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1993 • 3,605 citations

Tumor Angiogenesis: A New Significant and Independent Prognostic Indicator in Early-Stage Breast Carcinoma

1992 • 1,799 citations

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

1996 • 1,670 citations

Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

1995 • 1,421 citations

Hyperplasia of Lymphatic Vessels in VEGF-C Transgenic Mice

1997 • 1,280 citations

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

1998 • 1,192 citations

Cardiovascular Failure in Mouse Embryos Deficient in VEGF Receptor-3

1998 • 876 citations

The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

1996 • 855 citations

Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis.

1997 • 832 citations

Proteolytic processing regulates receptor specificity and activity of VEGF-C

1997 • 773 citations

Role of vascular endothelial growth factor in the regulation of angiogenesis

1999 • 733 citations

Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer

1995 • 622 citations

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1989 • 571 citations

Vascular endothelial growth factor C induces angiogenesis in vivo

1998 • 558 citations

Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells

1998 • 551 citations

VEGF and VEGF-C: Specific Induction of Angiogenesis and Lymphangiogenesis in the Differentiated Avian Chorioallantoic Membrane

1997 • 501 citations

Clinical importance of the determination of tumor angiogenesis in breast carcinoma: much more than a new prognostic tool.

1995 • 441 citations

Vascular Endothelial Growth Factor-C (VEGF-C/VEGF-2) Promotes Angiogenesis in the Setting of Tissue Ischemia

1998 • 353 citations

Role of Vegf-Flt Receptor System in Normal and Tumor Angiogenesis

1995 • 332 citations

Vascular Endothelial Growth Factors VEGF-B and VEGF-C Are Expressed in Human Tumors

1998 • 328 citations

A novel in situ hybridization signal amplification method based on the deposition of biotinylated tyramine.

1995 • 316 citations

Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3.

1998 • 315 citations

Flt-1 but not KDR/Flk-1 tyrosine kinase is a receptor for placenta growth factor, which is related to vascular endothelial growth factor.

1996 • 298 citations

The vesiculo-vacuolar organelle (VVO): a distinct endothelial cell structure that provides a transcellular pathway for macromolecular extravasation

1996 • 266 citations

The Short and Long Forms of Type XVIII Collagen Show Clear Tissue Specificities in Their Expression and Location in Basement Membrane Zones in Humans

1998 • 252 citations

Predictors of axillary lymph node metastases in patients with T1 breast carcinoma

1997 • 214 citations

Electron microscopic observations on lymphatic capillaries and the structural components of the connective tissue-lymph interface

1970 • 210 citations

Expression of the Vascular Endothelial Growth Factor C Receptor VEGFR-3 in Lymphatic Endothelium of the Skin and in Vascular Tumors

1998 • 206 citations

Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors.

1994 • 163 citations

Transmural Coupling of Fluid Flow in Microcirculatory Network and Interstitium in Tumors

1997 • 144 citations

Receptors of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in fetal and adult human kidney

1998 • 142 citations

Complete primary structure of two variant forms of human type XVIII collagen and tissue-specific differences in the expression of the corresponding transcripts

1998 • 121 citations

Lack of lymphangiogenesis in human primary cutaneous melanoma. Consequences for the mechanism of lymphatic dissemination.

1997 • 88 citations

Differences in lymphatic and blood capillary permeability: ultrastructural-functional correlations.

1987 • 19 citations

VEGF-B binds to VEGFR-1 and regulates plasminogen activator activity in endothelial cells

1998 • 6 citations

Predictors of Axillary Node Metastases in Patients with T1 Breast Carcinoma

1999 • 2 citations