Role of IgE in atopic dermatitis

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

The Staphylococcal Enterotoxins and Their Relatives

1990 • 1,914 citations

Staphylococcus aureus in the lesions of atopic dermatitis

1974 • 864 citations

Evidence for compartmentalization of functional subsets of CD2+ T lymphocytes in atopic patients.

1990 • 807 citations

Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects.

1991 • 676 citations

Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens.

1993 • 525 citations

Human epidermal Langerhans cells express the high affinity receptor for immunoglobulin E (Fc epsilon RI).

1992 • 490 citations

Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes.

1987 • 449 citations

BASOPHILS IN ALLERGEN-INDUCED PATCH TEST SITES IN ATOPIC DERMATITIS

1982 • 422 citations

Double-blind, controlled, crossover study of cyclosporin in adults with severe refractory atopic dermatitis

1991 • 419 citations

High Frequency of IL-4–Producing CD4+ Allergen-Specific T Lymphocytes in Atopic Dermatitis Lesional Skin

1991 • 397 citations

Epidermal Langerhans cells from normal human skin bind monomeric IgE via Fc epsilon RI.

1992 • 388 citations

Skin-derived aeroallergen-specific T-cell clones of Th2 phenotype in patients with atopic dermatitis

1992 • 388 citations

Recombinant interferon gamma therapy for atopic dermatitis

1993 • 306 citations

Allergen presentation by epidermal Langerhans' cells from patients with atopic dermatitis is mediated by IgE.

1990 • 293 citations

Human recombinant interleukin 4 induces Fc epsilon R2/CD23 on normal human monocytes.

1988 • 280 citations

Decreased interferon gamma and increased interleukin-4 production in atopic dermatitis promotes IgE synthesis

1992 • 277 citations

Human atopen-specific types 1 and 2 T helper cell clones.

1991 • 273 citations

Age-related serum immunoglobulin E levels in healthy subjects and in patients with allergic disease

1980 • 269 citations

IL-4 inhibits the synthesis of IFN-gamma and induces the synthesis of IgE in human mixed lymphocyte cultures.

1990 • 262 citations

Shifts in interleukin-4 and interferon-γ production by T cells of patients with elevated serum IgE levels and the modulatory effects of these lymphokines on spontaneous IgE synthesis

1991 • 224 citations

Natural History of Sensitizations in Atopic Dermatitis

1992 • 196 citations

Serum IgD and IgE concentrations in immunodeficiency diseases.

1975 • 193 citations

Serum eosinophil cationic protein (ECP) is a sensitive measure for disease activity in atopic dermatitis

1992 • 168 citations

Secretion of leukotriene C and other arachidonic acid metabolites by macrophages challenged with immunoglobulin E immune complexes.

1982 • 165 citations

Genetic and environmental factors affecting the development of atopy through age 4 in children of atopic parents: a prospective randomized study of food allergen avoidance

1992 • 161 citations

Enhanced IL-4 Production and IL-4 Receptor Expression in Atopic Dermatitis and Their Modulation by Interferon-Gamma

1992 • 151 citations

The case for steroid—antibiotic combinations

1977 • 134 citations

Atopic disease and serum immunoglobulin-E

2006 • 132 citations

Atopic dermatitis

1982 • 126 citations

IgE-dependent cytokine production by human peripheral blood mononuclear phagocytes.

1991 • 118 citations

Effectiveness of house dust-mite allergen avoidance through clean room therapy in patients with atopic dermatitis

1992 • 116 citations

Importance of Inhalant Allergens in Atopic Dermatitis**From the Allergy Clinic, Temple University Hospital and Medical School, Philadelphia, Penna.

1949 • 106 citations

IgE Levels in Atopic Dermatitis

1973 • 105 citations

Combination of patch test and IgE for dust mite antigens differentiates 130 patients with atopic dermatitis into four groups

1992 • 100 citations

A current perspective on the role of eosinophils in dermatologic diseases

1991 • 93 citations

The immunopathogenic role of food hypersensitivity in atopic dermatitis.

1992 • 84 citations

T helper cells grown with hapten‐modified cultured Langerhans' cells produce interleukin 4 and stimulate IgE production by B cells

1989 • 82 citations

Atopic eczema: role of microorganisms on the skin surface

1992 • 69 citations

Immunoglobulin E and Immunoglobulin G Subclass Distribution in vivo and Relationship to in vitro Generation of Interferon-Gamma and Neopterin in Patients with Severe Atopic Dermatitis

1988 • 67 citations

Immunopathology of atopic dermatitis

1992 • 62 citations

The relationship between positive aeroallergen patch test reactions and aeroallergen exacerbations of atopic dermatitis

1989 • 61 citations

Prurigo Besnier (atopic dermatitis) with special reference to the role of allergic factors. II. The evaluation of the results of skin reactions.

1961 • 59 citations

Evidence suggesting involvement of interleukin-4 (IL-4) production in spontaneous in vitro IgE synthesis in patients with atopic dermatitis

1991 • 56 citations

Immunoglobulin E-dependent stimulation of human alveolar macrophages: significance in type 1 hypersensitivity.

1986 • 56 citations

Patients with severe atopic dermatitis have activated circulating basophils

1993 • 53 citations

Eczema in primary immune-deficiencies. Clues to the pathogenesis of atopic dermatitis with special reference to the Wiskott-Aldrich syndrome.

1985 • 51 citations

Monocytes from patients with atopic dermatitis are primed for superoxide production

1992 • 46 citations

Natural history of sensitizations in atopic dermatitis. A 3-year follow-up in 250 children: food allergy and high risk of respiratory symptoms

1992 • 42 citations

Roles of eosinophils in allergy

1992 • 41 citations

IgE antibodies to Pityrosporum orbiculare and Staphylococcus aureus in patients with very high serum total IgE

1992 • 36 citations

Interferon-alpha therapy in atopic dermatitis.

1992 • 32 citations

DERMATOLOGY AND GENERAL MEDICINE.

1929 • 25 citations

Expression of the high affinity IgE-receptor on human Langerhans' cells. Elucidating the role of epidermal IgE in atopic eczema.

1992 • 22 citations

IgE levels in atopic dermatitis

1973 • 21 citations

Regulation of the Low Affinity IgE Fc Receptor (CD23) in Atopic Dermatitis

1993 • 13 citations

The detection of IgE-secreting cells in the peripheral blood of patients with atopic dermatitis

1992 • 9 citations