Skin-derived aeroallergen-specific T-cell clones of Th2 phenotype in patients with atopic dermatitis

Diagnostic Features of Atopic Dermatitis

1980 • 4,910 citations

IL-4 directs the development of Th2-like helper effectors.

1990 • 1,261 citations

Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells.

1990 • 954 citations

Evidence for compartmentalization of functional subsets of CD2+ T lymphocytes in atopic patients.

1990 • 807 citations

Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production.

1991 • 705 citations

Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production.

1991 • 641 citations

BASOPHILS IN ALLERGEN-INDUCED PATCH TEST SITES IN ATOPIC DERMATITIS

1982 • 422 citations

High Frequency of IL-4–Producing CD4+ Allergen-Specific T Lymphocytes in Atopic Dermatitis Lesional Skin

1991 • 397 citations

A new murine CD4+ T cell subset with an unrestricted cytokine profile.

1989 • 374 citations

Induction of human IgE synthesis requires interleukin 4 and T/B cell interactions involving the T cell receptor/CD3 complex and MHC class II antigens.

1989 • 331 citations

Immunoglobulin E in Dermatoses

1969 • 298 citations

Allergen presentation by epidermal Langerhans' cells from patients with atopic dermatitis is mediated by IgE.

1990 • 293 citations

The Langerhans Cell

1983 • 265 citations

Active participation of eosinophils in patch test reactions to inhalant allergens in patients with atopic dermatitis

1988 • 210 citations

Profiles of lymphokine activities and helper function for IgE in human T cell clones

1988 • 204 citations

Eczematous reactions in atopic patients caused by epicutaneous testing with inhalant allergens

1986 • 172 citations

Atopic dermatitis and aeroallergen contact sensitivity

1988 • 151 citations

Heterogeneity of helper/inducer T lymphocytes. III. Responses of IL-2- and IL-4-producing (Th1 and Th2) clones to antigens presented by different accessory cells.

1990 • 144 citations

A study of the role of house dust mite in atopic dermatitis

1988 • 128 citations

Comparison of diversity and function of house dust mite‐specific T lymphocyte clones from atopic and non‐atopic donors

1990 • 113 citations

Monoclonal antibodies reactive with the mouse interleukin 5 receptor.

1989 • 103 citations

Characterization of grass pollen reactive T-cell lines derived from lesional atopic skin

1991 • 93 citations

Associated expression of CD1 antigen and Fc receptor for IgE on epidermal Langerhans cells from patients with atopic dermatitis.

1988 • 79 citations

Clonal expansion of human T lymphocytes initiated by dendritic cells.

1989 • 57 citations

A monoclonal anti-IgE antibody against an epitope (amino acids 367-376) in the CH3 domain inhibits IgE binding to the low affinity IgE receptor (CD23).

1988 • 40 citations

Total and specific IgE levels in patients with atopic dermatitis. The correlation between prick testing, clinical history of allergy, and in vitro quantification of IgE during clinical exacerbation and remission*

1979 • 28 citations

Interleukin-4 Promotes the Expansion of Skin-Infiltrating Lymphocytes from Atopic Dermatitis In Vitro

1991 • 25 citations

Comparison of lymphokine secretion and responsiveness of human T cell clones isolated in IL-4 and in IL-2

1991 • 22 citations

Different effects of IL-2 addition or antibody crosslinking on T-cell subset stimulation by CD3 antibodies

1986 • 13 citations

Human peripheral blood B cell subpopulations: surface IgD+ cells respond to pokeweed mitogen with plasma cell differentiation.

1986 • 6 citations

Differential induction of cytokine-specific mRNA in human PBL after in vitro culture with either IL2 or IL4

1991 • 2 citations