Human papillomavirus DNA and abnormal p53 expression in carcinoma of the urinary bladder

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

p53 Mutations in Human Cancers

1991 • 8,133 citations

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1990 • 3,896 citations

Mutations in the p53 gene occur in diverse human tumour types

1989 • 2,765 citations

Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53

1990 • 2,587 citations

The p53 proto-oncogene can act as a suppressor of transformation

1989 • 2,019 citations

Increased expression of mutant forms of p53 oncogene in primary lung cancer

1990 • 1,045 citations

Identification of p53 Gene Mutations in Bladder Cancers and Urine Samples

1991 • 891 citations

Wild-type p53 can inhibit oncogene-mediated focus formation.

1989 • 738 citations

Wild-type p53 activates transcription in vitro

1992 • 609 citations

Analysis of p53 expression in human tumours: an antibody raised against human p53 expressed in Escherichia coli

1992 • 335 citations

p53 point mutation in HPV negative human cervical carcinoma cell lines.

1991 • 271 citations

Occurrence of p53 gene deletions and human papilloma virus infection in human head and neck cancer.

1992 • 215 citations

Frequency of molecular alterations affecting ras protooncogenes in human urinary tract tumors.

1985 • 191 citations

Inactivation of the retinoblastoma gene in human bladder and renal cell carcinomas.

1991 • 184 citations

Expression of mutant p53, c-erbB-2 and the epidermal growth factor receptor in transitional cell carcinoma of the human urinary bladder

1991 • 181 citations

p53 Protein alterations in human testicular cancer including pre‐invasive intratubular germ‐cell neoplasia

1991 • 133 citations

High frequency of human papillomavirus infection in carcinoma of the urinary bladder

1992 • 104 citations

p53 immunohistochemistry in transitional cell carcinoma and dysplasia of the urinary bladder correlates with disease progression

1993 • 94 citations

Status of c-myc, p53 and retinoblastoma genes in human papillomavirus positive and negative squamous cell carcinomas of the anus.

1991 • 91 citations

High-risk human papillomavirus infections and overexpression of p53 protein as prognostic indicators in transitional cell carcinoma of the urinary bladder.

1993 • 90 citations

Biochemical properties of the growth suppressor/oncoprotein p53.

1992 • 73 citations

Ha-ras gene codon 12 mutation and DNA ploidy in urinary bladder carcinoma

1990 • 62 citations

Comparative analysis ofp53 protein immunoreactivity in prostatic, lung and breast carcinomas

1992 • 62 citations

Origins of human cancer: A comprehensive review

1992 • 59 citations

Presence and physical state of HPV DNA in prostate and urinary‐tract tissues

1992 • 59 citations

In situ hybridization and immunohistochemistry of p53 tumor suppressor gene in human esophageal carcinoma.

1992 • 40 citations

p53 Antigen in cervical condylomata, intraepithelial neoplasia, and carcinoma: Relationship to hpv infection and integration

1993 • 34 citations

Immunohistochemical analysis of p53 expression in anal squamous neoplasia.

1993 • 31 citations

Aberrant p53 protein expression in cervical intra‐epithelial neoplasia

1993 • 18 citations

Ultrastructural localization of human papilloma virus by nonradioactive in situ hybridization on tissue of human cervical intraepithelial neoplasia.

1992 • 12 citations