In situ hybridization and immunohistochemistry of p53 tumor suppressor gene in human esophageal carcinoma.

Mutations in the p53 gene occur in diverse human tumour types

1989 • 2,765 citations

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

1989 • 1,214 citations

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

1988 • 1,140 citations

Increased expression of mutant forms of p53 oncogene in primary lung cancer

1990 • 1,045 citations

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation

1984 • 761 citations

Growth regulation of a cellular tumour antigen, p53, in nontransformed cells

1984 • 524 citations

Isolation of human‐p53‐specific monoclonal antibodies and their use in the studies of human p53 expression

1986 • 508 citations

Overexpression and mutation of p53 in epithelial ovarian cancer.

1991 • 464 citations

Frequent mutation of the p53 gene in human esophageal cancer.

1990 • 393 citations

p53 cellular tumor antigen: analysis of mRNA levels in normal adult tissues, embryos, and tumors.

1985 • 380 citations

Activating Mutations for Transformation by p53 Produce a Gene Product That Forms an hsc70-p53 Complex with an Altered Half-Life

1988 • 298 citations

Genetic basis for p53 overexpression in human breast cancer.

1991 • 287 citations

p53 gene mutations in Barrett's epithelium and esophageal cancer.

1991 • 266 citations

Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens.

1991 • 262 citations

p53 expression in colorectal tumors.

1991 • 243 citations

Role of the p53 protein in cell proliferation as studied by microinjection of monoclonal antibodies.

1984 • 216 citations

High frequency of somatically acquired p53 mutations in small-cell lung cancer cell lines and tumors

1993 • 207 citations

Reduction to homozygosity involving p53 in esophageal cancers demonstrated by the polymerase chain reaction.

1991 • 162 citations

17p allelic deletions and p53 protein overexpression in Barrett's adenocarcinoma.

1991 • 138 citations

Differential localization of mRNAs of collagen types I and II in chick fibroblasts, chondrocytes, and corneal cells by in situ hybridization using cDNA probes.

1986 • 125 citations

p53 Cellular Tumor Antigen: Analysis of mRNA Levels in Normal Adult Tissues, Embryos, and Tumors

1985 • 117 citations

Role of the p53 Protein in Cell Proliferation as Studied by Microinjection of Monoclonal Antibodies

1984 • 64 citations

Primary pigmented nodular adrenocortical disease (PPNAD): immunohistochemical and in situ hybridization analysis of steroidogenic enzymes in eight cases.

1992 • 56 citations

Co-localization of EGF transcripts and peptides by combined immunohistochemistry and in situ hybridization.

1990 • 19 citations

Modulation of p53 gene expression and cytokeratin 18 in retinoid-mediated invasion suppressed lung carcinoma cells

1991 • 18 citations