Excision Repair in Mammalian Cells

DNA Repair and Mutagenesis

2006 • 4,725 citations

The Metabolic Basis of Inherited Disease

1990 • 4,327 citations

DNA repair and mutagenesis

1996 • 2,289 citations

REPAIR OF OXIDATIVE DAMAGE TO DNA: Enzymology and Biology

1994 • 1,435 citations

Interaction of the p53-Regulated Protein Gadd45 with Proliferating Cell Nuclear Antigen

1994 • 941 citations

Mammalian DNA nucleotide excision repair reconstituted with purified protein components

1995 • 833 citations

Proliferating cell nuclear antigen is required for DNA excision repair

1992 • 809 citations

DNA Repair Helicase: a Component of BTF2 (TFIIH) Basic Transcription Factor

1993 • 795 citations

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3.

1994 • 666 citations

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair

1994 • 657 citations

Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair.

1994 • 646 citations

Mechanisms of DNA Excision Repair

1994 • 560 citations

The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.

1990 • 552 citations

Transcription-Coupled Repair and Human Disease

1994 • 501 citations

Specific Binding of Chromosomal Protein HMG1 to DNA Damaged by the Anticancer Drug Cisplatin

1992 • 492 citations

Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II

1994 • 473 citations

Reconstitution of Human DNA Repair Excision Nuclease in a Highly Defined System

1995 • 460 citations

The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor

1994 • 432 citations

Cdk-activating kinase complex is a component of human transcription factor TFIIH

1995 • 431 citations

Mismatch Repair, Genetic Stability, and Cancer

1994 • 429 citations

Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.

1992 • 428 citations

Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23.

1994 • 394 citations

The structural basis of specific base-excision repair by uracil–DNA glycosylase

1995 • 390 citations

RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

1995 • 387 citations

Structure and function of the multifunctional DNA-repair enzyme exonuclease III

1995 • 382 citations

The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor.

1994 • 381 citations

Inhibition of DNA replication factor RPA by p53

1993 • 380 citations

Transcript cleavage by RNA polymerase II arrested by a cyclobutane pyrimidine dimer in the DNA template.

1994 • 357 citations

HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease.

1994 • 343 citations

DNA Polymerase β Conducts the Gap-filling Step in Uracil-initiated Base Excision Repair in a Bovine Testis Nuclear Extract

1995 • 317 citations

Specific association between the human DNA repair proteins XPA and ERCC1.

1994 • 304 citations

DNA REPAIR GENES AND PROTEINS OF SACCHAROMYCES CEREVISIAE

1993 • 301 citations

MAMMALIAN GENES INDUCED BY RADIATION; Activation of Genes Associated with Growth Control

1992 • 284 citations

The in vitro replication of DNA containing the SV40 origin.

1990 • 268 citations

Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin.

1992 • 246 citations

Purification of PCNA as a nucleotide excision repair protein

1992 • 228 citations

Requirement for the replication protein SSB in human DMA excision repair

1991 • 227 citations

Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts.

1994 • 223 citations

Human DNA Repair Excision Nuclease

1995 • 216 citations

DNA REPAIR IN HUMANS

1995 • 213 citations

Comparative analysis of binding of human damaged DNA-binding protein (XPE) and Escherichia coli damage recognition protein (UvrA) to the major ultraviolet photoproducts: T[c,s]T, T[t,s]T, T[6-4]T, and T[Dewar]T.

1993 • 208 citations

The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells.

1993 • 203 citations

Complementation of DNA repair in xeroderma pigmentosum group A cell extracts by a protein with affinity for damaged DNA.

1991 • 200 citations

Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics

1993 • 193 citations

The General Transcription-Repair Factor TFIIH Is Recruited to the Excision Repair Complex by the XPA Protein Independent of the TFIIE Transcription Factor

1995 • 188 citations

Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins.

1994 • 186 citations

UV light-induced DNA synthesis arrest in HeLa cells is associated with changes in phosphorylation of human single-stranded DNA-binding protein.

1994 • 186 citations

Genetic diversity of UV-sensitive DNA repair mutants of Chinese hamster ovary cells.

1981 • 173 citations

DNA repair by eukaryotic nucleotide excision nuclease. Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and of thymine dimer by Xenopus laevis oocytes.

1993 • 131 citations

DNA polymerase delta is involved in the cellular response to UV damage in human cells.

1994 • 110 citations

DNA Polymerases Required for Repair of UV-Induced Damage in Saccharomyces cerevisiae

1995 • 101 citations

Isolation of active recombinant XPG protein, a human DNA repair endonuclease.

1994 • 92 citations

Determination of minimum substrate size for human excinuclease.

1994 • 91 citations

The multifunctional TFIIH complex and transcriptional control

1994 • 88 citations

Biochemical heterogeneity in xeroderma pigmentosum complementation group E

1992 • 86 citations

UV damage-specific DNA-binding protein in xeroderma pigmentosum complementation group E

1991 • 84 citations

Structure and Function of the UvrB Protein

1995 • 82 citations

Replication protein A mutants lacking phosphorylation sites for p34cdc2 kinase support DNA replication.

1994 • 80 citations

Defective postreplication repair in xeroderma pigmentosum variant fibroblasts.

1990 • 70 citations

Excision Repair in Man and the Molecular Basis of Xeroderma Pigmentosum Syndrome

1993 • 69 citations

Increased UV‐induced SCEs but normal repair of DNA damage in p53‐deficient mouse cells

1994 • 60 citations

Phosphorylated and unphosphorylated forms of human single-stranded DNA-binding protein are equally active in simian virus 40 DNA replication and in nucleotide excision repair.

1995 • 60 citations

A conserved 5‘ to 3‘ exonuclease activity in the yeast and human nucleotide excision repair proteins RAD2 and XPG.

1994 • 56 citations

Preferential repair of the transcribed DNA strand in the dihydrofolate reductase gene throughout the cell cycle in UV-irradiated human cells

1995 • 42 citations

Human andE.coliexcinucleases are affected differently by the sequence context of acetylaminofluorene–guanine adduct

1994 • 37 citations

Human xeroderma pigmentosum group G gene encodes a DNA endonuclease

1994 • 36 citations