Comparison of mouse and human HOX-4 complexes defines conserved sequences involved in the regulation of Hox-4.4.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication

1987 • 1,050 citations

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 • 964 citations

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

1991 • 856 citations

Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

1991 • 698 citations

Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation

1989 • 612 citations

A nuclear DNA attachment element mediates elevated and position-independent gene activity

1989 • 597 citations

Murine Developmental Control Genes

1990 • 594 citations

Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells

1990 • 524 citations

Expression of the homeobox Hox-4 genes and the specification of position in chick wing development

1991 • 394 citations

Variations of cervical vertebrate after expression of a Hox-1.1 transgene in mice

1990 • 371 citations

Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body.

1991 • 344 citations

A quantitative analysis of the effect of all-trans-retinoic acid on the pattern of chick wing development

1985 • 312 citations

Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression.

1991 • 286 citations

Interaction of specific nuclear factors with the nuclease-hypersensitive region of the chicken adult β-globin gene: Nature of the binding domain

1985 • 255 citations

Involvement of the Chox-4 chicken homeobox genes in determination of anteroposterior axial polarity during limb development

1991 • 223 citations

Two steps in the evolution of Antennapedia-class vertebrate homeobox genes.

1989 • 212 citations

Two gene members of the murine HOX-5 complex show regional and cell-type specific expression in developing limbs and gonads.

1989 • 176 citations

Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2.

1988 • 151 citations

The Hox-4.8 gene is localized at the 5′ extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development

1991 • 135 citations

HOX4 genes encode transcription factors with potential auto- and cross-regulatory capacities.

1991 • 130 citations

Plasmid and bacteriophage vectors for excision of intact inserts

1987 • 127 citations

Primary structure and developmental expression pattern of Hox 3.1, a member of the murine Hox 3 homeobox gene cluster.

1988 • 119 citations

Spatial regulation of homeobox gene fusions in the embryonic central nervous system of transgenic mice

1988 • 113 citations

Separate elements cause lineage restriction and specify boundaries of Hox-1·1 expression

1991 • 105 citations

Hox-2.3 upstream sequences mediate lacZ expression in intermediate mesoderm derivatives of transgenic mice

1990 • 101 citations

The mouse Hox-1.4 gene: primary structure, evidence for promoter activity and expression during development

1989 • 100 citations

Mouse Hox-3.4: homeobox sequence and embryonic expression patterns compared with other members of the Hox gene network

1990 • 98 citations

Overexpression of a homeodomain protein confers axis-forming activity to uncommitted xenopus embryonic cells

1991 • 88 citations

Complementary homeo protein gradients in developing limb buds.

1989 • 88 citations

Primary structure and embryonic expression pattern of the mouse Hox-4.3* homeobox gene

1990 • 80 citations

Evidence for positive and negative regulation of the Hox-3.1 gene.

1990 • 77 citations

Region-specific enhancers near two mammalian homeo box genes define adjacent rostrocaudal domains in the central nervous system.

1990 • 76 citations

Position-specific activity of the Hox1.1 promoter in transgenic mice

1990 • 69 citations

Position-specific activity of the Hox 1.1 promoter in transgenic mice

1990 • 67 citations

A regulatory region from the mouse Hox-2.2 promoter directs gene expression into developing limbs

1991 • 41 citations

Remarkable intron and exon sequence conservation in human and mouse homeobox Hox 1.3 genes.

1989 • 29 citations

Remarkable Intron and Exon Sequence Conservation in Human and Mouse Homeobox Hox 1.3 Genes

1989 • 5 citations