Treatment of patients with advanced colorectal cancer with cisplatin, 5-fluorouracil, and leucovorin

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Toxicity and response criteria of the Eastern Cooperative Oncology Group

1982 • 10,605 citations

Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma.

1989 • 911 citations

A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal carcinoma.

1988 • 513 citations

A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma.

1987 • 452 citations

Effect of excess folates and deoxyinosine on the activity and site of action of 5-fluorouracil.

1981 • 287 citations

Overview of clinical trials using 5-fluorouracil and leucovorin for the treatment of colorectal cancer

1989 • 220 citations

A phase III trial of 5-fluorouracil and leucovorin in the treatment of advanced colorectal cancer. A mayo clinic/north central cancer treatment group study

1989 • 209 citations

Cytotoxicity of 5-fluoro-2'-deoxyuridine: requirement for reduced folate cofactors and antagonism by methotrexate.

1978 • 196 citations

Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice.

1981 • 195 citations

A phase III study comparing the clinical utility of four regimens of 5-Fluorouracil.A preliminary report

1977 • 150 citations

Induction chemotherapy with cisplatin, fluorouracil, and high-dose leucovorin for locally advanced head and neck cancer: a clinical and pharmacologic analysis.

1990 • 106 citations

Chemotherapy of large bowel cancer.

1982 • 104 citations

Basis for natural variation in sensitivity to 5-fluorouracil in mouse and human cells in culture.

1979 • 104 citations

No benefit of ifosfamide in Ewing's sarcoma: a nonrandomized study of the French Society of Pediatric Oncology.

1992 • 101 citations

The enhancement of 5-fluorouracil antimetabolic activity by leucovorin, menadione and α-tocopherol

1982 • 91 citations

Approximate Confidence Intervals for Probabilities of Survival and Quantiles in Life-Table Analysis

1982 • 82 citations

Levamisole as an adjuvant to chemotherapy in extensive bronchogenic carcinoma. A veterans administration lung cancer group study

1982 • 70 citations

A phase II trial of 5-fluorouracil and high-dose intravenous leucovorin in gastric carcinoma.

1987 • 61 citations

A randomized study of inpatient versus outpatient continuous infusion chemotherapy for patients with locally advanced head and neck cancer

1989 • 45 citations

Cisplatin, 5‐fluorouracil, and high‐dose oral leucovorin for advanced head and neck cancer

1989 • 32 citations

The Expanding Role of Folates and Fluoropyrimidines in Cancer Chemotherapy

1988 • 31 citations

5-FU/leucovorin: biochemical modulation that works?

1987 • 28 citations

Cisplatin, 5-fluorouracil, and high-dose oral leucovorin for advanced head and neck cancer

1989 • 20 citations

A study of various strategies to enhance the cytotoxic activity of 5-fluorouracil/leucovorin in human colorectal cancer cell lines.

1989 • 10 citations

Progress Report on Studies of FAM-CF for Gastric Cancer and Intraperitoneal Administration of FUra-CF Followed by Cisplatin (DDP)

1988 • 6 citations

Phase I clinical trial of cisplatin given i.v. with 5-fluorouracil and high-dose folinic acid

1990 • 5 citations

Phase II Evaluation of 5-Fluorouracil, Folinic Acid and Cisplatin in Advanced-Stage Colorectal Adenocarcinoma

1989 • 5 citations

Phase I Trial of Semustine Plus Weekly Fluorouracil and High-Dose Leucovorin Calcium in Patients With Advanced Colorectal Cancer

1989 • 2 citations