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Molecular cloning and functional characterization of the OCTN2 transporter at the RBE4 cells, an in vitro model of the blood–brain barrier

Data up to Jan 2025

Published2003
Citations41
References57

Total Citations Per Year

Abstract

References (57)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Carnitine--metabolism and functions

1983 • 1,620 citations

Molecular and Functional Identification of Sodium Ion-dependent, High Affinity Human Carnitine Transporter OCTN2

1998 • 694 citations

Physiology of the CSF and Blood-Brain Barriers

1996 • 569 citations

Tight junctions of the blood-brain barrier.

2000 • 490 citations

Cellular and molecular aspects of drug transport in the kidney

2000 • 445 citations

Carnitine function and requirements during the life cycle

1992 • 337 citations

cDNA Sequence, Transport Function, and Genomic Organization of Human OCTN2, a New Member of the Organic Cation Transporter Family

1998 • 336 citations

Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.

1999 • 328 citations

Regulation of gamma‐glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells

1994 • 313 citations

ORGANIC CATION TRANSPORTERS IN INTESTINE, KIDNEY, LIVER, AND BRAIN

1998 • 312 citations

Molecular aspects of hepatobiliary transport

1997 • 304 citations

Molecular and Functional Characterization of Organic Cation/Carnitine Transporter Family in Mice

2000 • 291 citations

Long‐term acetyl‐L‐carnitine treatment in Alzheimer's disease

1991 • 233 citations

ROLE OF ORGANIC CATION TRANSPORTERS IN DRUG ABSORPTION AND ELIMINATION

1998 • 205 citations

Functional characterization and chromosomal localization of a cloned taurine transporter from human placenta

1994 • 205 citations

Vaccinia-T7 RNA polymerase expression system: Evaluation for the expression cloning of plasma membrane transporters

1991 • 157 citations

Functional relevance of carnitine transporter OCTN2 to brain distribution of<scp>l</scp>‐carnitine and acetyl‐<scp>l</scp>‐carnitine across the blood–brain barrier

2001 • 155 citations

Cellular energy metabolism during fetal development

1972 • 150 citations

Utilization of Citrate, Acetylcarnitine, Acetate, Pyruvate and Glucose for the Synthesis of Acetylcholine in Rat Brain Slices

1981 • 140 citations

Cerebral endothelial cells release TNF-alpha after stimulation with cell walls of Streptococcus pneumoniae and regulate inducible nitric oxide synthase and ICAM-1 expression via autocrine loops.

1999 • 126 citations

Turnover of carnitine by rat tissues

1975 • 123 citations

Functional and pharmacological characterization of human Na+-carnitine cotransporter hOCTN2

2000 • 117 citations

Acetyl-l-carnitine as a precursor of acetylcholine

1990 • 111 citations

Sodium gradient-stimulated transport of l-carnitine into renal brush border membrane vesicles: Kinetics, specificity, and regulation by dietary carnitine

1984 • 110 citations

Cerebral Endothelial Cells Release TNF-α After Stimulation with Cell Walls of Streptococcus pneumoniae and Regulate Inducible Nitric Oxide Synthase and ICAM-1 Expression Via Autocrine Loops

1999 • 106 citations

Molecular Cloning and Characterization of High-Affinity Carnitine Transporter from Rat Intestine

1998 • 102 citations

Superiority of L-propionylcarnitine vs L-carnitine in improving walking capacity in patients with peripheral vascular disease: an acute, intravenous, double-blind, cross-over study

1992 • 99 citations

The distribution and role of carnitine in the mammalian brain

1982 • 93 citations

Carnitine, carnitine acyltransferases, and rat brain function

1982 • 92 citations

Carnitine: Metabolism and clinical chemistry

1989 • 90 citations

Mutations in Novel Organic Cation Transporter (OCTN2), an Organic Cation/Carnitine Transporter, with Differential Effects on the Organic Cation Transport Function and the Carnitine Transport Function

1999 • 84 citations

Characterization of <scp>l</scp>-carnitine transport by rat kidney brush-border-membrane vesicles

1995 • 76 citations

Neuroprotective activity of acetyl‐L‐carnitine: Studies in vitro

1994 • 74 citations

Conversion of butyrobetaine to carnitine in the rat in vivo.

1974 • 67 citations

The Uptake of Carnitine by Slices of Rat Cerebral Cortex

1981 • 66 citations

Carnitine--a known compound, a novel function in neural cells.

1996 • 60 citations

Conversion of butyrobetaine to carnitine in the rat in vivo

1974 • 59 citations

Functional Expression of the Serotonin Transporter in Immortalized Rat Brain Microvessel Endothelial Cells

2000 • 54 citations

[44] Amplification, storage, and replication of libraries

1987 • 50 citations

Carnitine Biosynthesis: Identification of the cDNA Encoding Human γ-Butyrobetaine Hydroxylase

1998 • 48 citations

Cellular energy metabolism during fetal development

1976 • 48 citations

Acetyl-l-carnitine modulates glucose metabolism and stimulates glycogen synthesis in rat brain

1998 • 35 citations

Evidence for an Asymmetrical Uptake of L-Carnitine in the Blood-Brain Barrierin Vitro

1997 • 35 citations

Effect of externally added carnitine on the synthesis of acetylcholine in rat cerebral cortex cells

1995 • 35 citations

Sodium-dependent carnitine transport in human placental choriocarcinoma cells

1996 • 34 citations

Transport of Carnitine in Neuroblastoma NB-2a Cells

1995 • 30 citations

Blood–Brain Barrier Controls Carnitine Level in the Brain: A Study on a Model System with RBE4 Cells

2000 • 26 citations

[L-carnitine: metabolism, functions and value in pathology].

1992 • 26 citations

Characteristics of L-Carnitine Transport in Cultured Human Hepatoma HLF Cells

1999 • 23 citations

l-Carnitine uptake into primary rat cortical cultures: Interaction with GABA

1994 • 21 citations

Purification of carnitine carrier from rat brain mitochondria.

1993 • 19 citations

Synergistic Effect of Choline and Carnitine on Acetylcholine Synthesis in Neuroblastoma NB-2a Cells

1994 • 16 citations

Studies on the transport of carnitine in the brain using synaptosomes isolated from guinea-pig cerebral cortex

1983 • 13 citations

Transport of carnitine in RBE4 cells - an in vitro model of blood-brain barrier

1996 • 11 citations

Transport of [ 3 H]MPP + in an immortalized rat brain microvessel endothelial cell line (RBE 4)

2001 • 9 citations

Studies of the expression and characterization of various transport systems at RBE4 cells, an in vitro model of the blood-brain barrier

2003 • 1 citations

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