From vesicle docking to endocytosis: Intermediate reactions of exocytosis

Mechanisms of intracellular protein transport

1994 • 2,280 citations

EVIDENCE FOR RECYCLING OF SYNAPTIC VESICLE MEMBRANE DURING TRANSMITTER RELEASE AT THE FROG NEUROMUSCULAR JUNCTION

1973 • 2,122 citations

A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

1993 • 1,893 citations

Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse

1994 • 1,485 citations

The role of calcium in neuromuscular facilitation

1968 • 1,331 citations

Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function

1993 • 1,302 citations

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

1992 • 1,274 citations

Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells.

1982 • 1,010 citations

Microdomains of High Calcium Concentration in a Presynaptic Terminal

1992 • 837 citations

TURNOVER OF TRANSMITTER AND SYNAPTIC VESICLES AT THE FROG NEUROMUSCULAR JUNCTION

1973 • 835 citations

Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding

1995 • 816 citations

Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals

1995 • 760 citations

Calcium dependence of the rate of exocytosis in a synaptic terminal

1994 • 746 citations

Colocalization of ion channels involved in frequency selectivity and synaptic transmission at presynaptic active zones of hair cells

1990 • 639 citations

Alien intracellular calcium chelators attenuate neurotransmitter release at the squid giant synapse

1991 • 638 citations

Compartmentalization of the submembrane calcium activity during calcium influx and its significance in transmitter release

1985 • 609 citations

Calcium ions, active zones and synaptic transmitter release

1988 • 609 citations

Specificity and regulation of a synaptic vesicle docking complex

1994 • 601 citations

Multiple calcium-dependent processes related to secretion in bovine chromaffin cells

1993 • 524 citations

The kinetics of synaptic vesicle recycling measured at single presynaptic boutons

1993 • 523 citations

ATP-dependent inositide phosphorylation required for Ca2+-activated secretion

1995 • 508 citations

Calcium-dependence of catecholamine release from bovine adrenal medullary cells after exposure to intense electric fields

1982 • 500 citations

Synaptotagmin I is a high affinity receptor for clathrin AP-2: Implications for membrane recycling

1994 • 483 citations

The role of Rab3A in neurotransmitter release

1994 • 481 citations

Effects of mutant rat dynamin on endocytosis

1993 • 453 citations

Dynamics of synaptic vesicle fusion and membrane retrieval in synaptic terminals

1994 • 449 citations

Strategic location of calcium channels at transmitter release sites of frog neuromuscular synapses

1990 • 398 citations

Rabphilin-3A, a Putative Target Protein for smg p25A/rab3A p25 Small GTP-Binding Protein Related to Synaptotagmin

1993 • 386 citations

Synaptic Vesicles and Exocytosis

1994 • 371 citations

Friends and family: The role of the rab GTPases in vesicular traffic

1993 • 364 citations

Residual Ca2 + and short-term synaptic plasticity

1994 • 353 citations

The effect of temperature on the synaptic delay at the neuromuscular junction.

1965 • 349 citations

Phosphatidylinositol transfer protein required for ATP-dependent priming of Ca2+-activated secretion

1993 • 346 citations

Localization of calcium signals by a mobile calcium buffer in frog saccular hair cells

1994 • 343 citations

Kinetics of the secretory response in bovine chromaffin cells following flash photolysis of caged Ca2+

1994 • 343 citations

The role of clathrin, adaptors and dynamin in endocytosis

1994 • 343 citations

Subcellular Calcium Transients Visualized by Confocal Microscopy in a Voltage-Clamped Vertebrate Neuron

1990 • 341 citations

Short-term synaptic plasticity is altered in mice lacking synapsin I

1993 • 332 citations

Neurotransmitter release: fusion or ‘kiss-and-run’?

1994 • 327 citations

Buffering of calcium in the vicinity of a channel pore

1992 • 325 citations

Calcium domains associated with individual channels can account for anomalous voltage relations of CA-dependent responses

1984 • 324 citations

Regulation by synapsin I and Ca(2+)‐calmodulin‐dependent protein kinase II of the transmitter release in squid giant synapse.

1991 • 318 citations

Endocytosis of synaptic vesicle membrane at the frog neuromuscular junction.

1984 • 317 citations

Role of presynaptic calcium ions and channels in synaptic facilitation and depression at the squid giant synapse.

1982 • 291 citations

Vesicle pool mobilization during action potential firing at hippocampal synapses

1995 • 289 citations

Calcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants.

1994 • 286 citations

Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes

1990 • 284 citations

Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytosis

1993 • 282 citations

Imaging of cytosolic Ca2+ transients arising from Ca2+ stores and Ca2+ channels in sympathetic neurons

1988 • 281 citations

The role of presynaptic calcium in short-term enhancement at the hippocampal mossy fiber synapse

1994 • 275 citations

HPC-1 is associated with synaptotagmin and omega-conotoxin receptor.

1992 • 275 citations

Inhibition of endocytosis by elevated internal calcium in a synaptic terminal

1994 • 261 citations

Time course of transmitter release calculated from simulations of a calcium diffusion model

1992 • 258 citations

A post-docking role for synaptobrevin in synaptic vesicle fusion

1994 • 255 citations

Releasable pools and the kinetics of exocytosis in adrenal chromaffin cells

1994 • 254 citations

Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin.

1993 • 253 citations

A MOLECULAR DESCRIPTION OF SYNAPTIC VESICLE MEMBRANE TRAFFICKING

1994 • 248 citations

Inositol-1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin II.

1994 • 244 citations

Ca2+-dependent recycling of synaptic vesicles at the frog neuromuscular junction.

1980 • 231 citations

Evidence for the involvement of Rab3A in Ca(2+)-dependent exocytosis from adrenal chromaffin cells.

1994 • 224 citations

A dual effect of calcium ions on neuromuscular facilitation

1968 • 216 citations

Calcineurin Inhibition of Dynamin I GTPase Activity Coupled to Nerve Terminal Depolarization

1994 • 215 citations

Optical monitoring of transmitter release and synaptic vesicle recycling at the frog neuromuscular junction.

1993 • 214 citations

Calcium in motor nerve terminals associated with posttetanic potentiation

1989 • 212 citations

Absence of synaptotagmin disrupts excitation-secretion coupling during synaptic transmission.

1994 • 206 citations

Concentration Profiles of Intracellular Calcium in the Presence of a Diffusible Chelator

1986 • 196 citations

Mechanisms of Membrane Fusion

1993 • 195 citations

Functional properties of multiple synaptotagmins in brain

1994 • 195 citations

Role of residual calcium in synaptic depression and posttetanic potentiation: Fast and slow calcium signaling in nerve terminals

1991 • 193 citations

Time course of Ca2+ concentration triggering exocytosis in neuroendocrine cells.

1994 • 191 citations

A triggered mechanism retrieves membrane in seconds after Ca(2+)-stimulated exocytosis in single pituitary cells

1994 • 177 citations

Inhibition of Clathrin Assembly by High Affinity Binding of Specific Inositol Polyphosphates to the Synapse-specific Clathrin Assembly Protein AP-3

1995 • 174 citations

Interaction of synaptotagmin with the cytoplasmic domains of neurexins

1993 • 170 citations

The role of calcium ions in tetanic and post‐tetanic increase of miniature end‐plate potential frequency.

1978 • 156 citations

Exogenous synapsin I promotes functional maturation of developing neuromuscular synapses

1992 • 147 citations

SNAP-mediated protein–protein interactions essential for neurotransmitter release

1995 • 146 citations

The exocytotic fusion pore and neurotransmitter release

1994 • 140 citations

Millisecond studies of secretion in single rat pituitary cells stimulated by flash photolysis of caged Ca2+.

1993 • 126 citations

Synaptotagmin and neurotransmitter release

1993 • 125 citations

Doc2: A Novel Brain Protein Having Two Repeated C2-like Domains

1995 • 124 citations

Localization of individual calcium channels at the release face of a presynaptic nerve terminal

1994 • 122 citations

A Functional Role for GTP-Binding Proteins in Synaptic Vesicle Cycling

1993 • 109 citations

Synaptic vesicle exocytosis: Molecules and models

1994 • 107 citations

Synaptotagmin: A calcium-sensitive inhibitor of exocytosis?

1993 • 107 citations

Clostridial neurotoxins as tools to investigate the molecular events of neurotransmitter release

1994 • 101 citations

A role for soluble NSF attachment proteins (SNAPs) in regulated exocytosis in adrenal chromaffin cells.

1995 • 99 citations

The inositol high-polyphosphate series blocks synaptic transmission by preventing vesicular fusion: a squid giant synapse study.

1994 • 94 citations

Changes in miniature endplate potential frequency during repetitive nerve stimulation in the presence of Ca2+, Ba2+, and Sr2+ at the frog neuromuscular junction.

1981 • 86 citations

SNAPs and NSF: general members of the fusion apparatus

1995 • 85 citations

Exo-endocytosis and closing of the fission pore during endocytosis in single pituitary nerve terminals internally perfused with high calcium concentrations.

1994 • 74 citations

The spatial distribution of calcium signals in squid presynaptic terminals.

1993 • 72 citations

Cytosolic Ca2+ gradients, Ca2+ binding proteins and synaptic plasticity

1993 • 53 citations

The COOH terminus of synaptotagmin mediates interaction with the neurexins.

1994 • 52 citations

Evidence for a presynaptic blockage of transmission in a temperature‐sensitive mutant of Drosophila

1983 • 42 citations

Synaptic targeting domains of synapsin I revealed by transgenic expression in photoreceptor cells.

1994 • 31 citations

Docking of chromaffin granules—A necessary step in exocytosis?

1987 • 31 citations