Subcellular Calcium Transients Visualized by Confocal Microscopy in a Voltage-Clamped Vertebrate Neuron

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells.

1979 • 1,648 citations

Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores

1989 • 1,616 citations

Role of ion flux in the control of c-fos expression

1986 • 1,006 citations

Stimulus-transcription coupling in neurons: role of cellular immediate-early genes

1989 • 973 citations

Photochemically generated cytosolic calcium pulses and their detection by fluo-3

1989 • 820 citations

Depolarization and calcium entry in squid giant axons

1971 • 729 citations

Measurement of cytosolic free Ca2+ in individual small cells using fluorescence microscopy with dual excitation wavelengths

1985 • 660 citations

Calcium gradients in single smooth muscle cells revealed by the digital imaging microscope using Fura-2

1985 • 660 citations

Fluorescent Probes of Cell Signaling

1989 • 649 citations

Compartmentalization of the submembrane calcium activity during calcium influx and its significance in transmitter release

1985 • 609 citations

The effect of cyanide on the efflux of calcium from squid axons

1969 • 486 citations

Intracellular Ca2+ activates a fast voltage-sensitive K+ current in vertebrate sympathetic neurones

1982 • 418 citations

Two distinct Ca-dependent K currents in bullfrog sympathetic ganglion cells.

1985 • 415 citations

Myoplasmic binding of fura-2 investigated by steady-state fluorescence and absorbance measurements

1988 • 362 citations

Regulation of neuronal function by calcium

1989 • 302 citations

Calcium diffusion modeling in a spherical neuron. Relevance of buffering properties

1990 • 299 citations

Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.

1988 • 294 citations

Imaging of cytosolic Ca2+ transients arising from Ca2+ stores and Ca2+ channels in sympathetic neurons

1988 • 281 citations

Presynaptic calcium diffusion from various arrays of single channels. Implications for transmitter release and synaptic facilitation

1985 • 274 citations

Fluorescence measurement and photochemical manipulation of cytosolic free calcium

1988 • 248 citations

Release of calcium ions linked to the activation of potassium conductance in a caffeine‐treated sympathetic neurone.

1980 • 236 citations

Relationship between transmitter release and presynaptic calcium influx when calcium enters through discrete channels.

1986 • 207 citations

The Dynamics of Free Calcium in Dendritic Spines in Response to Repetitive Synaptic Input

1987 • 205 citations

Role for microsomal Ca storage in mammalian neurones?

1984 • 201 citations

Location of subunits within the acetylcholine receptor by electron image analysis of tubular crystals from Torpedo marmorata.

1987 • 195 citations

Distribution of two distinct Ca2+ -ATPase-like proteins and their relationships to the agonist-sensitive calcium store in adrenal chromaff in cells

1989 • 185 citations

Calcium as a modulator of the immediate-early gene cascade in neurons

1988 • 179 citations

Regional Changes in Calcium Underlying Contraction of Single Smooth Muscle Cells

1987 • 179 citations

Rhythmic hyperpolarizations and depolarization of sympathetic ganglion cells induced by caffeine

1976 • 159 citations

Simultaneous recording of calcium transients in skeletal muscle using high- and low-affinity calcium indicators

1988 • 149 citations

Aequorin response facilitation and intracellular calcium accumulation in molluscan neurones

1980 • 141 citations

Presynaptic calcium diffusion and the time courses of transmitter release and synaptic facilitation at the squid giant synapse

1983 • 135 citations

Agonists that suppress M-current elicit phosphoinositide turnover and Ca2+ transients, but these events do not explain M-current suppression

1988 • 132 citations

Peptidergic and muscarinic excitation at amphibian sympathetic synapses.

1983 • 128 citations

Three‐dimensional imaging in confocal imaging systems with finite sized detectors

1988 • 122 citations

Confocal microscopy: applications in neurobiology

1988 • 119 citations

Simulation of intracellular Ca2+ oscillation in a sympathetic neurone

1981 • 85 citations

Three‐Dimensional Imaging by Confocal Scanning Fluorescence Microscopy^a

1986 • 76 citations

Dynamics of intracellular calcium and its possible relationship to phasic transmitter release and facilitation at the frog neuromuscular junction

1984 • 72 citations

Ca-activated potassium current in vertebrate sympathetic neurones

1983 • 69 citations

Calcium localization in the sympathetic ganglion of the bullfrog and effects of caffeine

1980 • 65 citations

Calcium buffering and slow recovery kinetics of calcium‐dependent outward current in molluscan neurones.

1983 • 63 citations

Identification and function of intracellular calcium stores in axons and cell bodies of neurons.

1980 • 59 citations

ATP-dependent regulation of cytoplasmic free calcium in nerve terminals

1987 • 56 citations

Non-uniform Ca2+ buffer distribution in a nerve cell body

1980 • 52 citations

Confocal Light Microscopy

1986 • 40 citations

The role of diffusion in the photoresponse of an extraretinal photoreceptor of Aplysia.

1979 • 23 citations