ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

1997 • 7,177 citations

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

1993 • 6,009 citations

Caspases: the executioners of apoptosis

1997 • 4,674 citations

Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3

1997 • 3,130 citations

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

1996 • 3,065 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Programmed Cell Death in Animal Development

1997 • 2,690 citations

Inhibition of death receptor signals by cellular FLIP

1997 • 2,577 citations

FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis

1995 • 2,436 citations

Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death

1996 • 2,306 citations

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor.

1995 • 2,142 citations

The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation

1995 • 1,979 citations

X-linked IAP is a direct inhibitor of cell-death proteases

1997 • 1,961 citations

Apoptosis in the Failing Human Heart

1997 • 1,690 citations

Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

1993 • 1,387 citations

Life, death, and the pursuit of apoptosis.

1996 • 1,333 citations

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1997 • 1,316 citations

An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif

1993 • 1,049 citations

The molecular biology of apoptosis.

1996 • 963 citations

FADD/MORT1 Is a Common Mediator of CD95 (Fas/APO-1) and Tumor Necrosis Factor Receptor-induced Apoptosis

1996 • 780 citations

Signal Transduction by DR3, a Death Domain-Containing Receptor Related to TNFR-1 and CD95

1996 • 653 citations

Inhibition of ICE Family Proteases by Baculovirus Antiapoptotic Protein p35

1995 • 645 citations

A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.

1996 • 637 citations

Interaction of CED-4 with CED-3 and CED-9: A Molecular Framework for Cell Death

1997 • 635 citations

Human hsp27, Drosophila hsp27 and human alphaB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha-induced cell death.

1996 • 568 citations

RAIDD is a new 'death' adaptor molecule

1997 • 547 citations

The CARD domain: a new apoptotic signalling motif

1997 • 532 citations

Target Protease Specificity of the Viral Serpin CrmA

1997 • 517 citations

Apoptosis in pressure overload-induced heart hypertrophy in the rat.

1996 • 416 citations

harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-XL

1997 • 381 citations

Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53.

1997 • 375 citations

Visualization of Dystrophic Muscle Fibers in Mdx Mouse by Vital Staining with Evans Blue: Evidence of Apoptosis in Dystrophin-Deficient Muscle

1995 • 355 citations

CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis

1997 • 316 citations

Apoptosis precedes necrosis of dystrophin-deficient muscle

1995 • 229 citations

Cytotoxic mechanisms in inflammatory myopathies. Co-expression of Fas and protective Bcl-2 in muscle fibres and inflammatory cells

1997 • 132 citations

Interaction and Regulation of the Caenorhabditis elegans Death Protease CED-3 by CED-4 and CED-9

1997 • 130 citations

ACUTE INFANTILE SPINAL MUSCULAR ATROPHY

1990 • 99 citations

Apoptosis-related Proteins in Skeletal Muscle Fibers of Spinal Muscular Atrophy

1997 • 79 citations

Cloning and characterization of cDNAs for novel proteins with glutamic acid-proline dipeptide tandem repeats

1996 • 41 citations

A washable macromolecule from Fv2rr marrow negatively regulates DNA synthesis in erythropoietic progenitor cells BFU-E

1981 • 41 citations