Regulation of Prostaglandin H Synthase mRNA Levels and Prostaglandin Biosynthesis by Platelet-derived Growth Factor

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Ribonucleic acid isolated by cesium chloride centrifugation

1974 • 2,263 citations

Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences

1977 • 1,252 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

Enzyme immunoassays of eicosanoids using acetylcholine esterase as label: an alternative to radioimmunoassay

1985 • 716 citations

Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes.

1976 • 668 citations

Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence.

1988 • 604 citations

Functional role for c-myc in mitogenic response to platelet-derived growth factor

1984 • 578 citations

Biosynthesis of Prostaglandins

1991 • 503 citations

The enzymatic formation of prostaglandin E2 from arachidonic acid prostaglandins and related factors 32

1964 • 473 citations

Purification of the cyclooxygenase that forms prostaglandins. Demonstration of two forms of iron in the holoenzyme.

1976 • 435 citations

Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (cyclooxygenase).

1988 • 431 citations

Purification and characterisation of prostaglandin endoperoxide synthetase from sheep vesicular glands

1977 • 421 citations

Human platelet-derived growth factor stimulates prostaglandin synthesis by activation and by rapid de novo synthesis of cyclooxygenase.

1985 • 219 citations

Biosynthesis of Prostaglandins from Arachidonic Acid in Guinea Pig Lung

1965 • 201 citations

Identification and isolation of a mammalian protein which is antigenically and functionally related to the phospholipase A2 stimulatory peptide melittin.

1987 • 136 citations

Properties of a novel preparation of prostaglandin synthetase from sheep seminal vesicles

1971 • 135 citations

Stimulation of de novo synthesis of prostaglandin G/H synthase in human endothelial cells by phorbol ester.

1988 • 132 citations

Mechanism of enhanced fibroblast arachidonic acid metabolism by mononuclear cell factor.

1984 • 74 citations

Determination of the structure of the carbohydrate chains of prostaglandin endoperoxide synthase from sheep

2008 • 69 citations

Controlled tryptic digestion of prostaglandin H synthase. Characterization of protein fragments and enhanced rate of proteolysis of oxidatively inactivated enzyme.

1987 • 66 citations

Functional differentiation of cyclooxygenase and peroxidase activities of prostaglandin synthase by trypsin treatment. Possible location of a prosthetic heme binding site.

1988 • 49 citations

Possible involvement of cyclic AMP and calcium ion in prostaglandin E1-induced elevation of c-myc mRNA levels in Swiss 3T3 fibroblasts.

1986 • 46 citations

Protection of prostaglandin H synthase from trypsin upon binding of heme

1982 • 33 citations