Regulation of prostaglandin synthesis mediated by thrombin and b2 bradykinin receptors in a fibrosarcoma cell line

The Purification and Mechanism of Action of Human Antithrombin-Heparin Cofactor

1973 • 1,363 citations

Stimulation of Endothelial Cell Prostacyclin Production by Thrombin, Trypsin, and the Ionophore A 23187

1978 • 715 citations

Properties of the factor Xa binding site on human platelets.

1978 • 443 citations

[69] Hirudin as an inhibitor of thrombin

1970 • 311 citations

The Binding of Thrombin to the Surface of Human Platelets

1974 • 311 citations

Receptors for bradykinin in rabbit aortae

1977 • 258 citations

Nerve growth factor receptors on PC12 cells: ligand-induced conversion from low- to high-affinity states.

1980 • 255 citations

Effect of bradykinin and thrombin on prostacyclin synthesis in endothelial cells from calf and pig aorta and human umbilical cord vein

1980 • 249 citations

The measurement of thrombin in clotting blood by radioimmunoassay.

1976 • 235 citations

Slowly reversible binding of catecholamine to a nucleotide-sensitive state of the beta-adrenergic receptor.

1977 • 228 citations

Activation and function of human Hageman factor. The role of high molecular weight kininogen and prekallikrein.

1977 • 210 citations

Stimulation of prostaglandin synthesis by bradykinin and thrombin and their mechanisms of action on MC5-5 fibroblasts.

1976 • 196 citations

Functional consequences of agonist-mediated state transitions in the cholinergic receptor. Studies in cultured muscle cells.

1979 • 191 citations

Characterization of prostacyclin synthesis in cultured human arterial smooth muscle cells, venous endothelial cells and skin fibroblasts

1979 • 185 citations

Evidence for the formation of an ester between thrombin and heparin cofactor

1975 • 180 citations

Cardiac and Renal Prostaglandin I2

1978 • 174 citations

Prostaglandin production by mouse fibrosarcoma cells in culture: Inhibition by indomethacin and aspirin

1972 • 166 citations

Stimulation of prostaglandin biosynthesis by vasoactive substances in methylcholanthrene-transformed mouse BALB/3T3.

1976 • 155 citations

Regulation of endothelial cell cyclic nucleotide metabolism by prostacyclin.

1981 • 155 citations

Factor Va-dependent binding of factor Xa to human platelets.

1980 • 150 citations

De novo formation of vascular receptors for bradykinin

1978 • 137 citations

Use of a radioimmunoassay to study thrombin-induced release of PGI2 from cultured endothelium

1979 • 123 citations

Role of specific cell surface receptors in thrombin-stimulated cell division

1978 • 119 citations

Histamine stimulates prostacyclin synthesis in cultured human umbilical vein endothelial cells

1980 • 114 citations

Regulation of histamine-mediated prostacyclin synthesis in cultured human vascular endothelial cells

1981 • 111 citations

Stimulation of prostaglandin E synthesis in cultured human umbilical vein smooth muscle cells.

1976 • 111 citations

Serotonin receptor-mediated stimulation of bovine smooth muscle cell prostacyclin synthesis and its modulation by platelet-derived growth factor.

1981 • 106 citations

Insulin receptors convert to a higher affinity state subsequent to hormone binding. A two-state model for the insulin receptor.

1982 • 89 citations

Binding of thrombin to cultured human endothelial cells. Nonequilibrium aspects.

1980 • 72 citations

Anaphylactic release of a basophil kallikrein-like activity. I. Purification and characterization.

1979 • 72 citations

Functional consequences of agonist-mediated state transitions in the cholinergic receptor

1979 • 60 citations

Demonstration of a kinin-generating enzyme in the lysosomes of human polymorphonuclear leukocytes.

1973 • 58 citations

Bradykinin receptor-like binding studied with iodinated analogues

1980 • 57 citations

Evidence that the effects of thrombin on arachidonate metabolism in cultured human endothelial cells are not mediated by a high affinity receptor.

1980 • 53 citations

Cardiovascular actions of kinins in the rabbit

1979 • 53 citations

Internalization and degradation of thrombin and up regulation of thrombin-binding sites in corneal endothelial cells.

1981 • 51 citations

Prostacyclin and beta-adrenergic catecholamines inhibit arachidonate release and PGI2 synthesis by vascular endothelium

1981 • 50 citations

Subunits of human plasma carboxypeptidase N (kininase I; anaphylatoxin inactivator)

1974 • 40 citations

Bradykinin-stimulated release of [3H]arachidonic acid from phospholipids of HSDM1C1 cells: Comparison of diacyl phospholipids and plasmalogens as sources of prostaglandin precursors

1979 • 35 citations

Effects of Kinins on Organ Systems

1979 • 27 citations

Receptors for bradykinin and kallidin

1979 • 23 citations

Platelet release reaction and intracellular cGMP

1978 • 23 citations

A novel method for measuring cell surface-bound thrombin. Detection of iodination-induced changes in thrombin-binding affinity.

1982 • 21 citations

A sensitive radiochemical assay for angiotensin-converting enzyme (kinase II)

1975 • 16 citations

Differentiation of bradykinin receptors and of kininases with conformational analogues of bradykinin.

1978 • 10 citations

Genetically determined susceptibility to cancer

1981 • 8 citations

Reversal of bradykinin action: Possible involvement of prostaglandins or dual receptors

1980 • 5 citations

Thrombin-Induced Refractoriness Of PGI2 And Adenine Nucleotide Release From The Vascular Endothelium

1981 • 1 citations