Direct isolation of the functional human thymidine kinase gene with a cosmid shuttle vector.

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Rapid and efficient cosmid cloning

1981 • 1,897 citations

A simple method for DNA restriction site mapping

1976 • 1,025 citations

Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.

1978 • 804 citations

Expression of a Bacterial Gene in Mammalian Cells

1980 • 788 citations

Isolation of a transforming sequence from a human bladder carcinoma cell line

1982 • 776 citations

Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences

1981 • 657 citations

The Alu Family of Dispersed Repetitive Sequences

1982 • 611 citations

Genetic and physical linkage of exogenous sequences in transformed cells

1980 • 486 citations

Patterns of Integration of DNA Microinjected into Cultured Mammalian Cells: Evidence for Homologous Recombination Between Injected Plasmid DNA Molecules

1982 • 417 citations

Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences.

1981 • 387 citations

Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors.

1981 • 303 citations

Oncogenes in human tumor cell lines: molecular cloning of a transforming gene from human bladder carcinoma cells.

1982 • 268 citations

The mouse metallothionein-I gene is transcriptionally regulated by cadmium following transfection into human or mouse cells

1982 • 265 citations

Transformation and replication in mouse cells of a bovine papillomavirus--pML2 plasmid vector that can be rescued in bacteria.

1982 • 226 citations

Isolation of transforming DNA: Cloning the hamster aprt gene

1980 • 226 citations

Isolation of the chicken thymidine kinase gene by plasmid rescue

1980 • 208 citations

Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells.

1982 • 180 citations

Stable transformation of mouse L cells for human membrane T-cell differentiation antigens, HLA and beta 2-microglobulin: selection by fluorescence-activated cell sorting.

1983 • 153 citations

Versatile cosmid vectors for the isolation, expression, and rescue of gene sequences: studies with the human alpha-globin gene cluster.

1983 • 137 citations

Isolation of a genomic clone partially encoding human hypoxanthine phosphoribosyltransferase.

1982 • 117 citations

Identification of human genomic clones coding the major histocompatibility antigens HLA-a2 and HLA-B7 by DNA-mediated gene transfer.

1982 • 98 citations

Expression of the Mouse Dihydrofolate Reductase Complementary Deoxyribonucleic Acid in Simian Virus 40 Vectors

1981 • 96 citations

Molecular cloning and cell cycle-specific regulation of a functional human thymidine kinase gene.

1983 • 84 citations

Introduction and recovery of a selectable bacterial gene from the genome of mammalian cells.

1982 • 58 citations

Genomic cloning and preliminary characterization of the human thymidine kinase gene.

1983 • 50 citations

Fragment Spanning the SV40 Replication origin Is the Only DNA Sequence Required in cis for Viral Excision

1982 • 34 citations

Partial purification and characterization of the mRNA for human thymidine kinase and hypoxanthine/guanine phosphoribosyltransferase.

1982 • 20 citations

A plasmid that replicates in both mouse and E. coli cells.

1982 • 20 citations

Introduction and Recovery of a Selectable Bacterial Gene from the Genome of Mammalian Cells

1982 • 16 citations

Replication and amplification of recombinant plasmid molecules as extra chromosomal elements in transformed mammalian cells

1982 • 14 citations

Structure of thymidine kinase gene introduced into mouse Ltk− cells by a new injection method

1982 • 13 citations