Replication and amplification of recombinant plasmid molecules as extra chromosomal elements in transformed mammalian cells

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Isolation of High‐Molecular‐Weight DNA from Mammalian Cells

1973 • 1,723 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

1977 • 1,411 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

Trans-complementable copy-number mutants of plasmid ColE1

1980 • 975 citations

Transformation of rat cells by DNA of human adenovirus 5

1973 • 664 citations

Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences

1981 • 657 citations

Genetic and physical linkage of exogenous sequences in transformed cells

1980 • 486 citations

Synthesis of rabbit β-globin in cultured monkey kidney cells following infection with a SV40 β-globin recombinant genome

1979 • 355 citations

Gene Amplification and Drug Resistance in Cultured Murine Cells

1978 • 317 citations

Transforming DNA integrates into the host chromosome

1981 • 311 citations

Altering Genotype and Phenotype by DNA-Mediated Gene Transfer

1980 • 242 citations

Rabbit β-globin mRNA production in mouse L cells transformed with cloned rabbit β-globin chromosomal DNA

1979 • 191 citations

Biochemical Studies on the Herpes Simplex Virus-specified Deoxypyrimidine Kinase Activity

1974 • 190 citations

Biochemical transformation of mouse cells by fragments of herpes simplex virus DNA

1977 • 180 citations

Hybrid plasmids containing an active thymidine kinase gene of Herpes simplex virus 1

1979 • 147 citations

SV40 recombinants carrying rabbit β-globin gene coding sequences

1979 • 139 citations

Phenotype stabilisation and integration of transferred material in chromosome-mediated gene transfer

1979 • 104 citations

Deoxyribonucleic acid-mediated gene transfer in mammalian cells: molecular analysis of unstable transformants and their progression to stability.

1981 • 80 citations

DNA-mediated gene transfer without carrier DNA.

1981 • 69 citations

Transfer of human globin genes to erythroleukemic mouse cells.

1982 • 62 citations

Transfer of anchorage independence by isolated metaphase chromosomes in hamster cells

1977 • 36 citations

Transfer and expression of herpes simplex virus thymidine kinase and human globin genes in mammalian cells studied by spot hybridization assays

1981 • 12 citations