Isolation of a genomic clone partially encoding human hypoxanthine phosphoribosyltransferase.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid

1978 • 4,472 citations

A membrane-filter technique for the detection of complementary DNA

1966 • 3,996 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

Nucleotide sequence of the rightward operator of phage lambda.

1975 • 2,068 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences

1977 • 1,252 citations

Enzyme Defect Associated with a Sex-Linked Human Neurological Disorder and Excessive Purine Synthesis

1967 • 1,210 citations

Nature of Col E ₁ Plasmid Replication in Escherichia coli in the Presence of Chloramphenicol

1972 • 1,202 citations

Base sequence studies of 300 nucleotide renatured repeated human DNA clones

1981 • 605 citations

Human-tumor-derived cell lines contain common and different transforming genes

1981 • 455 citations

Molecular cloning and characterization of the human β-like globin gene cluster

1980 • 452 citations

The transfer and stable integration of the HSV thymidine kinase gene into mouse cells

1978 • 382 citations

Filter replicas and permanent collections of recombinant DNA plasmids

1979 • 355 citations

The use of drug-resistant markers to study the hybridization of mouse fibroblasts

1966 • 326 citations

Three different human tumor cell lines contain different oncogenes

1981 • 245 citations

Isolation and localization of DNA segments from specific human chromosomes

1980 • 220 citations

Human Bone Marrow Mesenchymal Stem Cell Behaviors on PCL/Gelatin Nanofibrous Scaffolds Modified with A Collagen IV-Derived RGD-Containing Peptide.

2014 • 215 citations

The isolation of high molecular weight DNA from whole organisms or large tissue masses

1978 • 171 citations

Analysis of the regions flanking the human insulin gene and sequence of an Alu family member

1980 • 153 citations

In vitro construction of bacteriophage lambda carrying segments of the Escherichia coli chromosome: selection of hybrids containing the gene for DNA ligase.

1975 • 142 citations

RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes.

1979 • 136 citations

Cloning of the yeast ribosomal DNA repeat unit in SstI and HindIII lambda vectors using genetic and physical size selections

1978 • 124 citations

Analysis of transcription of the human Alu family ubiquitous repeating element by eukaryotic RNA polymerase III

1981 • 122 citations

An electron microscope study of the DNA sequence organization of the human genome

1976 • 117 citations

Construction and characterization of a 2.5-kilobase procollagen clone.

1978 • 107 citations

The use of exonuclease III for preparing single stranded DNA for use as a template in the chain terminator sequencing method

1979 • 101 citations

A very large repeating unit of mouse DNA containing the 18S, 28S and 5.8S rRNA genes

1977 • 99 citations

DNA sequence of a major human leukocyte interferon gene.

1981 • 79 citations

Transformation of the gene for hypoxanthine phosphoribosyltransferase

1979 • 72 citations

Human and Mouse Hypoxanthine-Guanine Phosphoribosyltransferase: Dimers and Tetramers

1979 • 69 citations

Regional Localization of the Gene for Human Phosphoribosylpyrophosphate Synthetase on the X Chromosome

1979 • 64 citations

Expression of human genes for adenine phosphoribosyltransferase and hypoxanthine-guanine phosphoribosyltransferase after genetic transformation of mouse cells with purified human DNA

1980 • 49 citations

Cotransfer of linked eukaryotic genes and efficient transfer of hypoxanthine phosphoribosyltransferase by DNA-mediated gene transfer.

1980 • 44 citations

Processing steps and methylation in the formation of the ribosomal RNA of cultured Drosophila cells

1978 • 36 citations

Recent advances in the identification of enzyme abnormalities underlying excessive purine synthesis in man

1975 • 17 citations