STIM1 signalling controls store-operated calcium entry required for development and contractile function in skeletal muscle

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

2006 • 2,174 citations

Store-Operated Calcium Channels

2005 • 2,077 citations

STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx

2005 • 2,020 citations

STIM1, an essential and conserved component of store-operated Ca2+ channel function

2005 • 1,757 citations

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

2005 • 1,358 citations

Orai1 is an essential pore subunit of the CRAC channel

2006 • 1,305 citations

A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type

1998 • 998 citations

Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane

2006 • 772 citations

The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER–plasma membrane junctions

2006 • 630 citations

STIM1 carboxyl-terminus activates native SOC, Icrac and TRPC1 channels

2006 • 627 citations

Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca ²⁺ store depletion

2007 • 592 citations

CRACM1 Multimers Form the Ion-Selective Pore of the CRAC Channel

2006 • 555 citations

Large Store-operated Calcium Selective Currents Due to Co-expression of Orai1 or Orai2 with the Intracellular Calcium Sensor, Stim1

2006 • 537 citations

STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels

2007 • 491 citations

IL-4 Acts as a Myoblast Recruitment Factor during Mammalian Muscle Growth

2003 • 476 citations

Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release–activated calcium channels

2007 • 388 citations

Dynamic Assembly of TRPC1-STIM1-Orai1 Ternary Complex Is Involved in Store-operated Calcium Influx

2007 • 382 citations

Depletion of Ca²⁺ in the sarcoplasmic reticulum stimulates Ca²⁺ entry into mouse skeletal muscle fibres

2001 • 262 citations

Separation and Characterization of Currents through Store-operated CRAC Channels and Mg²⁺-inhibited Cation (MIC) Channels

2002 • 262 citations

Ca²⁺ signalling and muscle disease

2000 • 237 citations

Calcineurin Activity Is Required for the Initiation of Skeletal Muscle Differentiation

2000 • 231 citations

Emerging perspectives in store-operated Ca2+ entry: Roles of Orai, Stim and TRP

2006 • 215 citations

Interaction of STIM1 with Endogenously Expressed Human Canonical TRP1 upon Depletion of Intracellular Ca2+ Stores

2006 • 207 citations

STIM1 regulates Ca²⁺ entry via arachidonate‐regulated Ca²⁺‐selective (ARC) channels without store depletion or translocation to the plasma membrane

2006 • 181 citations

CRAC channels: activation, permeation, and the search for a molecular identity

2003 • 165 citations

Dysfunction of store-operated calcium channel in muscle cells lacking mg29

2002 • 161 citations

Elevated subsarcolemmal Ca ²⁺ in mdx mouse skeletal muscle fibers detected with Ca ²⁺ -activated K ⁺ channels

2000 • 159 citations

STIM2 protein mediates distinct store‐dependent and store‐independent modes of CRAC channel activation

2007 • 155 citations

TRPC3 Mediates T-cell Receptor-dependent Calcium Entry in Human T-lymphocytes

2003 • 129 citations

Store‐operated Ca²⁺ entry during intracellular Ca²⁺ release in mammalian skeletal muscle

2007 • 126 citations

Altered Primary Myogenesis in NFATC3−/− Mice Leads to Decreased Muscle Size in the Adult

2001 • 119 citations

The Ankyrin-B C-terminal Domain Determines Activity of Ankyrin-B/G Chimeras in Rescue of Abnormal Inositol 1,4,5-Trisphosphate and Ryanodine Receptor Distribution in Ankyrin-B (−/−) Neonatal Cardiomyocytes

2002 • 118 citations

Ryanodine receptors

2005 • 109 citations

Streptomycin reduces stretch-induced membrane permeability in muscles from mdx mice

2006 • 107 citations

Biochemical properties and cellular localisation of STIM proteins

2007 • 107 citations

Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx.

2007 • 103 citations

Mechanosensitive channel properties and membrane mechanics in mouse dystrophic myotubes

2007 • 97 citations

TRPC3 channels confer cellular memory of recent neuromuscular activity

2004 • 93 citations

Concerted regulation of skeletal muscle contractility by oxygen tension and endogenous nitric oxide

2003 • 90 citations

The calcineurin pathway links hyperpolarization (Kir2.1)-induced Ca2+ signals to human myoblast differentiation and fusion

2006 • 82 citations

A Store-operated Calcium Channel in Drosophila S2 Cells

2004 • 78 citations

Some assembly required: Constructing the elementary units of store-operated Ca2+ entry

2007 • 77 citations

Homer modulates NFAT-dependent signaling during muscle differentiation

2005 • 64 citations

New insights into the molecular mechanisms of store-operated Ca2+ signaling in T cells

2007 • 59 citations

Spontaneous and Repetitive Calcium Transients in C2C12 Mouse Myotubes during In Vitro Myogenesis

1997 • 49 citations

Function of a STIM1 Homologue in C. elegans: Evidence that Store-operated Ca2+ Entry Is Not Essential for Oscillatory Ca2+ Signaling and ER Ca2+ Homeostasis

2006 • 48 citations

CRAC channel activity in C. elegans is mediated by Orai1 and STIM1 homologues and is essential for ovulation and fertility

2007 • 42 citations

Ca²⁺ sparks are initiated by Ca²⁺ entry in embryonic mouse skeletal muscle and decrease in frequency postnatally

2003 • 36 citations

Calcium-dependent Gene Regulation in Myocyte Hypertrophy and Remodeling

2002 • 25 citations

Voltage‐ and ligand‐gated ryanodine receptors are functionally separated in developing C2C12 mouse myotubes

2000 • 21 citations

Interactions of the calcium ATPase with phospholamban and sarcolipin: structure, physiology and pathophysiology.

2004 • 7 citations