Orai1 is an essential pore subunit of the CRAC channel

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

2006 • 2,174 citations

Store-Operated Calcium Channels

2005 • 2,077 citations

STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx

2005 • 2,020 citations

STIM1, an essential and conserved component of store-operated Ca2+ channel function

2005 • 1,757 citations

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

2005 • 1,358 citations

CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca ²⁺ Entry

2006 • 1,285 citations

Calcium Signaling Mechanisms in T Lymphocytes

2001 • 841 citations

Genome-wide RNAi screen of Ca ²⁺ influx identifies genes that regulate Ca ²⁺ release-activated Ca ²⁺ channel activity

2006 • 838 citations

Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai

2006 • 797 citations

Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores.

1993 • 752 citations

Calcium release‐activated calcium current in rat mast cells.

1993 • 729 citations

Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels

1993 • 614 citations

Amplification of CRAC current by STIM1 and CRACM1 (Orai1)

2006 • 576 citations

Gene regulation mediated by calcium signals in T lymphocytes

2001 • 572 citations

Orai1 and STIM Reconstitute Store-operated Calcium Channel Function

2006 • 547 citations

Large Store-operated Calcium Selective Currents Due to Co-expression of Orai1 or Orai2 with the Intracellular Calcium Sensor, Stim1

2006 • 537 citations

PERMEATION AND SELECTIVITY OF TRP CHANNELS

2005 • 532 citations

Ca2+ channel selectivity at a single locus for high-affinity Ca2+ interactions

1995 • 277 citations

Separation and Characterization of Currents through Store-operated CRAC Channels and Mg²⁺-inhibited Cation (MIC) Channels

2002 • 262 citations

Permeation and Selectivity in Calcium Channels

2003 • 256 citations

CaT1 and the Calcium Release-activated Calcium Channel Manifest Distinct Pore Properties

2001 • 236 citations

A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients

2005 • 225 citations

Mg2+-dependent Gating and Strong Inward Rectification of the Cation Channel TRPV6

2003 • 155 citations

Regulation of CRAC Channel Activity by Recruitment of Silent Channels to a High Open-probability Gating Mode

2006 • 139 citations

Outer Pore Architecture of a Ca2+-selective TRP Channel

2004 • 131 citations

Conductance and permeation of monovalent cations through depletion-activated Ca2+ channels (ICRAC) in Jurkat T cells

1996 • 124 citations

Proteins, channels and crowded ions

2002 • 100 citations

Mechanisms of valence selectivity in biological ion channels

2006 • 85 citations

Monovalent cation permeability and Ca2+ block of the store-operated Ca2+ current I CRAC in rat basophilic leukemia cells

2002 • 79 citations

Ca2+ Modulation of Ca2+ Release-Activated Ca2+ Channels Is Responsible for the Inactivation of Its Monovalent Cation Current

2004 • 29 citations