The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER–plasma membrane junctions

A model for receptor-regulated calcium entry

1986 • 2,535 citations

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

2006 • 2,174 citations

Store-Operated Calcium Channels

2005 • 2,077 citations

STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx

2005 • 2,020 citations

Calcium Sparks: Elementary Events Underlying Excitation-Contraction Coupling in Heart Muscle

1993 • 1,917 citations

Capacitative calcium entry revisited

1990 • 1,499 citations

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

2005 • 1,358 citations

CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca ²⁺ Entry

2006 • 1,285 citations

Red fluorescent protein

2001 • 1,048 citations

Calcium Signaling Mechanisms in T Lymphocytes

2001 • 841 citations

Genome-wide RNAi screen of Ca ²⁺ influx identifies genes that regulate Ca ²⁺ release-activated Ca ²⁺ channel activity

2006 • 838 citations

Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane

2006 • 772 citations

Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores.

1993 • 752 citations

Calcium release‐activated calcium current in rat mast cells.

1993 • 729 citations

Gene regulation mediated by calcium signals in T lymphocytes

2001 • 572 citations

Shape, Size, and Distribution of Ca2+ Release Units and Couplons in Skeletal and Cardiac Muscles

1999 • 569 citations

Potentiation and inhibition of Ca²⁺ release‐activated Ca²⁺ channels by 2‐aminoethyldiphenyl borate (2‐APB) occurs independently of IP₃ receptors

2001 • 492 citations

Rapid inactivation of depletion-activated calcium current (ICRAC) due to local calcium feedback.

1995 • 370 citations

STIM Is a Ca 2+ Sensor Essential for Ca 2+ -Store-Depletion-Triggered Ca 2+ Influx

2005 • 342 citations

Modeling Buffered Ca2+ Diffusion Near the Membrane

1997 • 285 citations

Separation and Characterization of Currents through Store-operated CRAC Channels and Mg²⁺-inhibited Cation (MIC) Channels

2002 • 262 citations

Interference reflection microscopy in cell biology: methodology and applications

1985 • 232 citations

Imaging Calcium Entry Sites and Ribbon Structures in Two Presynaptic Cells

2003 • 190 citations

Characterization of T cell mutants with defects in capacitative calcium entry: genetic evidence for the physiological roles of CRAC channels.

1995 • 179 citations

Role of the Cytoskeleton in Calcium Signaling in NIH 3T3 Cells

1997 • 170 citations

Functional Co-localization of Transfected Ca2+-stimulable Adenylyl Cyclases with Capacitative Ca2+ Entry Sites

1996 • 168 citations

Direct measurement of SR release flux by tracking ‘Ca²⁺ spikes’ in rat cardiac myocytes

1998 • 161 citations

Visualization of localized store‐operated calcium entry in mouse astrocytes. Close proximity to the endoplasmic reticulum

2005 • 138 citations

Enhancement of calcium signalling dynamics and stability by delayed modulation of the plasma‐membrane calcium‐ATPase in human T cells

2002 • 121 citations

Store-operated Ca2+ entry: Vesicle fusion or reversible trafficking and de novo conformational coupling?

2005 • 55 citations

Calcium release and influx colocalize to the endoplasmic reticulum

1997 • 54 citations

Near‐visible ultraviolet light induces a novel ubiquitous calcium‐permeable cation current in mammalian cell lines

1998 • 51 citations

Does Actin Polymerization Status Modulate Ca2+Storage in Human Neutrophils? Release and Coalescence of Ca2+Stores by Cytochalasins

1997 • 11 citations