Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5‐HT_1A autoreceptor in vivo

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Psychopharmacology: The third generation of progress

1988 • 3,403 citations

Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites

1986 • 686 citations

The involvement of subtypes of the 5-HT1 receptor and of catecholaminergic systems in the behavioural response to 8-hydroxy-2-(di-n-Propylamino) tetralin in the rat

1984 • 678 citations

Acceleration of the effect of selected antidepressant drugs in major depression by 5-HT1A antagonists

1996 • 656 citations

Effectiveness of Pindolol With Selected Antidepressant Drugs in the Treatment of Major Depression

1995 • 323 citations

Interaction between a selective 5‐HT_1Areceptor antagonist and an SSRI in vivo: effects on 5‐HT cell firing and extracellular 5‐HT

1995 • 312 citations

Randomised, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment

1997 • 302 citations

Effect of Pindolol on the Function of Pre- and Postsynaptic 5-HT1A Receptors: In Vivo Microdialysis and Electrophysiological Studies in the Rat Brain

1996 • 179 citations

Effect of pindolol in hastening response to fluoxetine in the treatment of major depression: a double-blind, placebo-controlled trial

1997 • 177 citations

Activation of the 5-HT1A receptor subtype increases rat plasma ACTH concentration

1988 • 168 citations

Centrally acting hypotensive agents with affinity for 5‐HT_1A binding sites inhibit forskolin‐stimulated adenylate cyclase activity in calf hippocampus

1988 • 151 citations

Pharmacological characterization of 8‐OH‐DPAT‐induced inhibition of rat hippocampal 5‐HT release in vivo as measured by microdialysis

1989 • 137 citations

Effect of a selective 5‐HT reuptake inhibitor in combination with 5‐HT_1A and 5‐HT_1B receptor antagonists on extracellular 5‐HT in rat frontal cortex in vivo

1997 • 136 citations

Mixed agonist/antagonist properties of NAN-190 at 5-HT1A Receptors: Behavioural and in vivo brain microdialysis studies

1990 • 133 citations

Is pindolol a mixed agonist-antagonist at central serotonin (5-HT) receptors?

1986 • 131 citations

Central serotonin1A receptors: Respective distributions of encoding mRNA, receptor protein and binding sites by in situ hybridization histochemistry, radioimmunohistochemistry and autoradiographic mapping in the rat brain

1991 • 115 citations

Evidence for a repetitive (burst) firing pattern in a sub-population of 5-hydroxytryptamine neurons in the dorsal and median raphe nuclei of the rat

1995 • 111 citations

Application of brain microdialysis to study the pharmacology of the 5-HT1A autoreceptor

1990 • 110 citations

Further investigation of the in vivo pharmacological properties of the putative 5-HT1A antagonist, BMY 7378

1990 • 109 citations

Agonist/antagonist interactions with cloned human 5-HT1A receptors: variations in intrinsic activity studied in transfected HeLa cells

1992 • 104 citations

Serotonin1A Receptor Activation by Flesinoxan in Humans Body Temperature and Neuroendocrine Responses

1995 • 92 citations

Pharmacology of the hypothermic response to 5-HT1A receptor activation in humans

1990 • 89 citations

Activity of serotonin (5-HT) receptor agonists, partial agonists and antagonists at cloned human 5-HT1a receptors that are negatively coupled to adenylate cyclase in permanently transfected hela cells

1993 • 78 citations

Differential Effects of Ipsapirone on 5‐Hydroxytryptamine Release in the Dorsal and Median Raphe Neuronal Pathways

1996 • 73 citations

Effect of pindolol on endocrine and temperature responses to buspirone in healthy volunteers

1992 • 71 citations

Antagonism of 5-hydroxytryptamine1A (5-HT1A) receptor-mediated modulation of adenylate cyclase activity by pindolol and propranolol isomers

1988 • 69 citations

5-hydroxytryptamine (5-HT)1A receptors and the tail-flick response. I. 8-hydroxy-2-(di-n-propylamino) tetralin HBr-induced spontaneous tail-flicks in the rat as an in vivo model of 5-HT1A receptor-mediated activity.

1991 • 54 citations

Serotonergic Mechanisms Involved in the Exploratory Behaviour of Mice in a Fully Automated Two‐Compartment Black and White Test Box

1995 • 53 citations

Effects of MDL 73005EF on central pre- and postsynaptic 5-HT1A receptor function in the rat in vivo

1990 • 51 citations

Serotonin 5-HT1a receptor-mediated hypothermia in mice: Absence of spare receptors and rapid induction of tolerance

1992 • 48 citations

Assessment of relative efficacies of 5-HT1A receptor ligands by means of in vivo animal models

1996 • 40 citations

(−)-Pindolol and (±)-Tertatolol Affect Rat Hippocampal 5-HT Levels Through Mechanisms Involving Not Only 5-HT1A, But Also 5-HT1B Receptors

1996 • 35 citations

Effect of pindolol on hormone secretion and body temperature: Partial agonist effects

1996 • 34 citations

5-HT1A-mediated lower lip retraction: Effects of 5-HT1A agonists and antagonists

1993 • 34 citations

Antagonism by pindolol, but not betaxolol, of 8-OH-DPAT-induced facilitation of male rat sexual behavior

1989 • 33 citations

5-Hydroxytryptamine release in dorsal hippocampus of freely moving rats: Modulation by pindolol

1994 • 27 citations

Comparison of the effects of LSD and lisuride on A10 dopamine neurons in the rat

1983 • 25 citations

Raphe neurons: Firing rate correlates with size of drug response

1983 • 25 citations

The role of 5-HT1A autoreceptors and α1-Adrenoceptors in the inhibition of 5-HT release—II NAN-190 and SDZ 216-525

1996 • 24 citations

The role of hippocampal 5-hydroxytryptamine1a (5-HT1a) receptors in the anticonflict activity of β-adrenoceptor antagonists

1995 • 21 citations

Age-dependent β-adrenergic response of neuronal discharge in the raphe dorsalis: Evidence of a transient regulation

1988 • 13 citations

The role of 5-hydroxytryptamine1A (5-HT1A) receptors in the anticonflict activity of β-adrenoceptor antagonists

1994 • 11 citations