Further investigation of the in vivo pharmacological properties of the putative 5-HT1A antagonist, BMY 7378
Data up to Jan 2025
Total Citations Per Year
Abstract
References (33)
8-Hydroxy-2-(di-n-propylamino)-tetralin discriminates between subtypes of the 5-HT1 recognition site
1983 • 869 citations
Electrophysiological responses of serotoninergic dorsal raphe neurons to 5‐HT1A and 5‐HT1B agonists
1987 • 838 citations
Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites
1986 • 686 citations
The involvement of subtypes of the 5-HT1 receptor and of catecholaminergic systems in the behavioural response to 8-hydroxy-2-(di-n-Propylamino) tetralin in the rat
1984 • 678 citations
Functional Correlates of Serotonin 5-HT1Recognition Sites
1988 • 564 citations
8-hydroxy-2-(di-n-propylamino)tetralin, 8-OH-DPAT, a potent and selective simplified ergot congener with central 5-HT-receptor stimulating activity
1982 • 517 citations
Suppression of firing activity of 5-HT neurons in the dorsal raphe by alpha-adrenoceptor antagonists
1980 • 435 citations
Modification of 5‐HT neuron properties by sustained administration of the 5‐HT1A agonist gepirone: Electrophysiological studies in the rat brain
1987 • 429 citations
The comparative efficacy of buspirone and diazepam in the treatment of anxiety
1979 • 426 citations
The Pharmacology of a β2-Selective Adrenoceptor Antagonist (ICI 118,551)
1983 • 419 citations
5-HT1A receptor-related anxiolytics
1987 • 402 citations
Presynaptic 5-HT autoreceptors on serotonergic cell bodies and/or dendrites but not terminals are of the 5-HT1A subtype
1985 • 383 citations
A behavioural and biochemical study in mice and rats of putative selective agonists and antagonists for 5‐HT1 and 5‐HT2 receptors
1985 • 378 citations
Blockage of amphetamine induced motor stimulation and stereotypy in the adult rat following neonatal treatment with 6-hydroxydopamine
1973 • 350 citations
5‐HT1 agonists reduce 5‐hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis
1989 • 322 citations
(-)-Propranolol blocks the inhibition of serotonergic dorsal raphe cell firing by 5-HT1A selective agonists
1986 • 301 citations
Differential actions of serotonin antagonists on two behavioral models of serotonin receptor activation in the rat.
1984 • 299 citations
Differential effects of 5-hydroxytryptamine1A selective drugs on the 5-HT behavioral syndrome
1986 • 244 citations
Inhibition of serotonergic dorsal raphe neurons by systemic and iontophoretic administration of buspirone, a non-benzodiazepine anxiolytic drug
1986 • 231 citations
In Vivo Measurement of Extracellular 5‐Hydroxytryptamine in Hippocampus of the Anaesthetized Rat Using Microdialysis: Changes in Relation to 5‐Hydroxytryptaminergic Neuronal Activity
1989 • 227 citations
Evidence for the localization of 5HT1A binding sites on serotonin containing neurons in the raphe dorsalis and raphe centralis nuclei of the rat brain
1985 • 202 citations
Serotonergic mechanisms in the behavioral effects of buspirone and gepirone
1986 • 194 citations
Electrophysiologically-identified serotonin receptors in the rat CNS Effect of antidepressant treatment
1984 • 170 citations
Activation of the 5-HT1A receptor subtype increases rat plasma ACTH concentration
1988 • 168 citations
A survey of the pharmacological properties of metoprolol in animals and man
1975 • 153 citations
Pharmacological characterization of 8‐OH‐DPAT‐induced inhibition of rat hippocampal 5‐HT release in vivo as measured by microdialysis
1989 • 137 citations
8-Hydroxy-2-(di-n-propylamino) tetralin is devoid of activity at the 5-hydroxytryptamine autoreceptor in rat brain. Implications for the proposed link between the autoreceptor and the [3H] 5-HT recognition site
1984 • 132 citations
BMY 7378, a buspirone analog with high affinity, selectivity and low intrinsic activity at the 5-HT1A receptor in rat and guinea pig hippocampal membranes
1987 • 128 citations
Effects of the 5-hydroxytryptamine receptor antagonist, BMY 7378, on 5-hydroxytryptamine neurotransmission: electrophysiological studies in the rat central nervous system.
1988 • 107 citations
Open trial of buspirone in the treatment of major depressive disorder.
1986 • 83 citations
Electrophysiological assessment of putative antagonists of 5-hydroxytryptamine receptors: a single-cell study in the rat dorsal raphe nucleus
1989 • 51 citations
Biochemical and electrophysiological evidence for an agonist action of CM 57493 at pre- and postsynaptic 5-hydroxytryptamine1A receptors in brain.
1989 • 40 citations
Deleted Work
1955 • 0 citations