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Further investigation of the in vivo pharmacological properties of the putative 5-HT1A antagonist, BMY 7378

Data up to Jan 2025

Published1990
Citations109
References33

Total Citations Per Year

Abstract

References (33)

8-Hydroxy-2-(di-n-propylamino)-tetralin discriminates between subtypes of the 5-HT1 recognition site

1983 • 869 citations

Electrophysiological responses of serotoninergic dorsal raphe neurons to 5‐HT1A and 5‐HT1B agonists

1987 • 838 citations

Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites

1986 • 686 citations

The involvement of subtypes of the 5-HT1 receptor and of catecholaminergic systems in the behavioural response to 8-hydroxy-2-(di-n-Propylamino) tetralin in the rat

1984 • 678 citations

Functional Correlates of Serotonin 5-HT1Recognition Sites

1988 • 564 citations

8-hydroxy-2-(di-n-propylamino)tetralin, 8-OH-DPAT, a potent and selective simplified ergot congener with central 5-HT-receptor stimulating activity

1982 • 517 citations

Suppression of firing activity of 5-HT neurons in the dorsal raphe by alpha-adrenoceptor antagonists

1980 • 435 citations

Modification of 5‐HT neuron properties by sustained administration of the 5‐HT1A agonist gepirone: Electrophysiological studies in the rat brain

1987 • 429 citations

The comparative efficacy of buspirone and diazepam in the treatment of anxiety

1979 • 426 citations

The Pharmacology of a β2-Selective Adrenoceptor Antagonist (ICI 118,551)

1983 • 419 citations

5-HT1A receptor-related anxiolytics

1987 • 402 citations

Presynaptic 5-HT autoreceptors on serotonergic cell bodies and/or dendrites but not terminals are of the 5-HT1A subtype

1985 • 383 citations

A behavioural and biochemical study in mice and rats of putative selective agonists and antagonists for 5‐HT1 and 5‐HT2 receptors

1985 • 378 citations

Blockage of amphetamine induced motor stimulation and stereotypy in the adult rat following neonatal treatment with 6-hydroxydopamine

1973 • 350 citations

5‐HT1 agonists reduce 5‐hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis

1989 • 322 citations

(-)-Propranolol blocks the inhibition of serotonergic dorsal raphe cell firing by 5-HT1A selective agonists

1986 • 301 citations

Differential actions of serotonin antagonists on two behavioral models of serotonin receptor activation in the rat.

1984 • 299 citations

Differential effects of 5-hydroxytryptamine1A selective drugs on the 5-HT behavioral syndrome

1986 • 244 citations

Inhibition of serotonergic dorsal raphe neurons by systemic and iontophoretic administration of buspirone, a non-benzodiazepine anxiolytic drug

1986 • 231 citations

In Vivo Measurement of Extracellular 5‐Hydroxytryptamine in Hippocampus of the Anaesthetized Rat Using Microdialysis: Changes in Relation to 5‐Hydroxytryptaminergic Neuronal Activity

1989 • 227 citations

Evidence for the localization of 5HT1A binding sites on serotonin containing neurons in the raphe dorsalis and raphe centralis nuclei of the rat brain

1985 • 202 citations

Serotonergic mechanisms in the behavioral effects of buspirone and gepirone

1986 • 194 citations

Electrophysiologically-identified serotonin receptors in the rat CNS Effect of antidepressant treatment

1984 • 170 citations

Activation of the 5-HT1A receptor subtype increases rat plasma ACTH concentration

1988 • 168 citations

A survey of the pharmacological properties of metoprolol in animals and man

1975 • 153 citations

Pharmacological characterization of 8‐OH‐DPAT‐induced inhibition of rat hippocampal 5‐HT release in vivo as measured by microdialysis

1989 • 137 citations

8-Hydroxy-2-(di-n-propylamino) tetralin is devoid of activity at the 5-hydroxytryptamine autoreceptor in rat brain. Implications for the proposed link between the autoreceptor and the [3H] 5-HT recognition site

1984 • 132 citations

BMY 7378, a buspirone analog with high affinity, selectivity and low intrinsic activity at the 5-HT1A receptor in rat and guinea pig hippocampal membranes

1987 • 128 citations

Effects of the 5-hydroxytryptamine receptor antagonist, BMY 7378, on 5-hydroxytryptamine neurotransmission: electrophysiological studies in the rat central nervous system.

1988 • 107 citations

Open trial of buspirone in the treatment of major depressive disorder.

1986 • 83 citations

Electrophysiological assessment of putative antagonists of 5-hydroxytryptamine receptors: a single-cell study in the rat dorsal raphe nucleus

1989 • 51 citations

Biochemical and electrophysiological evidence for an agonist action of CM 57493 at pre- and postsynaptic 5-hydroxytryptamine1A receptors in brain.

1989 • 40 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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Further investigation of the in vivo pharmacological properties of the putative 5-HT1A… (1990) – European Journal of Pharmacology | Metascience Observatory Explorer